Comparative Omics Analyses in Plant Evolution

A special issue of Plants (ISSN 2223-7747).

Deadline for manuscript submissions: closed (28 February 2020) | Viewed by 4724

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Guest Editor
School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Singapore
Interests: comparative transcriptomics; plant evolution; co-expression; specialized metabolism
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Special Issue Information

Dear Colleagues,

Studying plant evolution can reveal principles of the emergence of novel traits, such as multicellularity, adaptation to terrestrial growth, sexual reproduction, and hormone signaling. Typically, the evolution of these traits is studied through comparative genomic and phylogenomic analyses, which assume that the traits emerge and evolve as gene families. However, genes and gene families form higher-order functional units (gene modules), such as protein complexes and enzymatic pathways, which employ multiple genes from different gene families. These gene modules can be identified by analyzing omics data, such as protein–protein interaction networks, and by identifying transcriptionally co-regulated (co-expressed) genes, among others. Therefore, a more rewarding approach to explain the evolution of new traits, adaptations, and gene functions should by necessity compare omics data across different experiments and species. However, the methods to compare omics data across experiments and species are still not fully developed.

This Special Issue is poised to address the studies, approaches, and databases that compare omics data, such as genomics, transcriptomics, proteomics, and metabolomics, across members of the Archaeplastida.

Dr. Marek Mutwil
Guest Editor

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Keywords

  • Gene function prediction
  • Comparative omics
  • Evolution of traits
  • Comparative databases
  • Reverse genetics

Published Papers (1 paper)

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11 pages, 1391 KiB  
Review
Co-regulation of Clustered and Neo-functionalized Genes in Plant-Specialized Metabolism
by Takayuki Tohge and Alisdair R. Fernie
Plants 2020, 9(5), 622; https://doi.org/10.3390/plants9050622 - 13 May 2020
Cited by 17 | Viewed by 4328
Abstract
Current findings of neighboring genes involved in plant specialized metabolism provide the genomic signatures of metabolic evolution. Two such genomic features, namely, (i) metabolic gene cluster and (ii) neo-functionalization of tandem gene duplications, represent key factors corresponding to the creation of metabolic diversity [...] Read more.
Current findings of neighboring genes involved in plant specialized metabolism provide the genomic signatures of metabolic evolution. Two such genomic features, namely, (i) metabolic gene cluster and (ii) neo-functionalization of tandem gene duplications, represent key factors corresponding to the creation of metabolic diversity of plant specialized metabolism. So far, several terpenoid and alkaloid biosynthetic genes have been characterized with gene clusters in some plants. On the other hand, some modification genes involved in flavonoid and glucosinolate biosynthesis were found to arise via gene neo-functionalization. Although the occurrence of both types of metabolic evolution are different, the neighboring genes are generally regulated by the same or related regulation factors. Therefore, the translation-based approaches associated with genomics, and transcriptomics are able to be employed for functional genomics focusing on plant secondary metabolism. Here, we present a survey of the current understanding of neighboring genes involved in plant secondary metabolism. Additionally, a genomic overview of neighboring genes of four model plants and transcriptional co-expression network neighboring genes to detect metabolic gene clusters in Arabidopsis is provided. Finally, the insights functional genomics have provided concerning the evolution and mechanistic regulation of both the formation and operation of metabolic neighboring clusters is discussed. Full article
(This article belongs to the Special Issue Comparative Omics Analyses in Plant Evolution)
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