Berries and Health: Bioactive Compounds in Functional Foods and Nutraceuticals

A Special Issue of Plants (ISSN 2223-7747) belonging to the section "Phytochemistry".

Deadline for manuscript submissions: closed (30 June 2026) | Viewed by 1612

Editors


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Guest Editor
Institute for Research and Development in Process Engineering, Biotechnology and Alternative Energies (CONICET-National University of Comahue), Neuquen, Argentina
Interests: plant-based food design and optimization; extraction emerging technologies for phenolic compounds; berry-derived functional foods and nutraceuticals; fiber-rich powdered ingredients; freeze-, spray-, and fluidized-bed-dried nutraceuticals; valorization of wild berries and fruit-processing by-products for functional food development

E-Mail Website
Guest Editor
Institute for Research and Development in Process Engineering, Biotechnology and Alternative Energies (CONICET-National University of Comahue), Neuquen, Argentina
Interests: valorization of fruit by-products; extraction technologies; polyphenols and dietary fiber from berries; pectin extraction; functional foods and ingredients; drying processes

Special Issue Information

Dear Colleagues,

Berries are rich sources of bioactive compounds, such as polyphenols, anthocyanins, and dietary fiber, with recognized antioxidant, anti-inflammatory, and gut-modulating properties. However, a gap persists between the development of specific functional foods and the evidence supporting their nutritional potential.

This Special Issue aims to highlight advances in the following areas:

  • Development of innovative berry-based functional foods (e.g., fortified snacks, beverages, baked goods, dairy products, and nutraceuticals).
  • Validation of health-related functionalities, for instance antioxidant activity, enzyme inhibition (e.g., α-glucosidase, pancreatic lipase), antiplatelet activity, microbiota modulation, or anti-inflammatory effects in relevant models, among others.
  • Technological and methodological approaches such as encapsulation, novel processing technologies, and in vitro gastrointestinal digestion models.
  • Development of functional foods and nutraceuticals from by-products derived from berry processing.

We encourage original research that report the design of specific berry-based functional foods or nutraceuticals together with the demonstration (at least through in vitro techniques) of specific bioactivities. Manuscripts solely evaluating the functional potential of liquid extracts derived from berries or berry by-products will not be considered for acceptance.

Dr. Daniela Salvatori
Dr. Paula Andrea Sette
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Plants is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • berries
  • berry by-products
  • functional foods
  • nutraceuticals

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Published Papers (1 paper)

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Research

21 pages, 2375 KB  
Article
Black and White Mulberry Extracts: Phytochemical Profile and In Vitro Antiatherogenic and Antiplatelet Properties
by Eirini Lantavou, Maria Xenaki, Sofia Bellou, Stavros Beteinakis, Alexios-Leandros Skaltsounis, Alexandros D. Tselepis, Despoina Pantazi and Panagiotis Stathopoulos
Plants 2026, 15(15), 2394; https://doi.org/10.3390/plants15152394 - 5 Aug 2026
Viewed by 1279
Abstract
Mulberry fruits are rich sources of bioactive phytochemicals with potential cardiovascular-relative bioactivity properties. In the present study, phenolic/alkaloid-enriched extracts from black (Morus nigra) and white (Morus alba) mulberries were chemically characterized and evaluated for their anti-atherogenic and antiplatelet activities [...] Read more.
Mulberry fruits are rich sources of bioactive phytochemicals with potential cardiovascular-relative bioactivity properties. In the present study, phenolic/alkaloid-enriched extracts from black (Morus nigra) and white (Morus alba) mulberries were chemically characterized and evaluated for their anti-atherogenic and antiplatelet activities in vitro. LC-HRMS analysis revealed distinct phytochemical profiles, with the black mulberry extract (BlackM) being characterized by a high abundance of anthocyanins, predominantly cyanidin- and pelargonidin-based glycosides, whereas the white mulberry extract (WhiteM) was particularly rich in pyrrolidine alkaloids, including morusimic acid isomers. Both extracts also contain flavonoids and phenolic acids, such as rutin, quercetin derivatives, and chlorogenic acid derivatives. BlackM markedly increased the resistance of low-density lipoprotein (LDL) to Cu2+-induced oxidation, whereas WhiteM more effectively inhibited the propagation phase of lipid peroxidation and significantly suppressed arachidonic acid-induced platelet aggregation. BlackM induced a modest, albeit non-significant, reduction in neutrophil extracellular trap (NET) formation. To the best of our knowledge, this is among the first studies to comparatively investigate the effects of black and white mulberry extracts on LDL oxidation, platelet aggregation and NETs formation. Overall, these findings support the potential use of mulberry-derived phytochemicals as functional food ingredients and nutraceuticals for the prevention of atherothrombotic cardiovascular disease. Full article
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