Rare and Imported Paediatric Infections

A special issue of Pharmacy (ISSN 2226-4787).

Deadline for manuscript submissions: closed (30 April 2019) | Viewed by 9720

Special Issue Editor


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Guest Editor
Paediatric Infectious Diseases Research Group, St Georges University of London, London, UK
Interests: infectious diseases; vaccine preventable diseases; paediatric allergy; public health; paediatrics and medical education

Special Issue Information

Dear Colleagues,

Changes in infectious disease transmission patterns are unprecedented in this current climate. There is a need for a better understanding of the causal relationships, in order to predict the future impacts of this on children’s health. In addition, health care workers are likely to see an increasingly number of cases due to human and environmental displacement. An international collaborative effort with an early and integrated model of care is required to resolve this. Meanwhile, there is urgent requirement for a study on the trend and pattern of these rare paediatric infectious diseases in our population. This study will undoubtedly elucidate the modes of indigenous transmission, treatment and preventive measures

In this Special Issue of Pharmacy, we are seeking, in particular, case reports, case series, and reviews that describe rare paediatric infectious diseases, vaccine preventable diseases and pharmocotherapy. Authors are also invited to submit articles or original research that might relate to imported infections, which may be endemic in other countries but rare in the region of study.

The principle aim of this Special Issue is to share good practices amongst health care providers, especially in relation to uncommon and rare infections in children and provide evidence-based practice for learning and educational development of health professionals.

Dr. Godwin Oligbu
Guest Editor

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Keywords

  • Infections
  • Paediatrics
  • Vaccines
  • Public health
  • Imported infections
  • Pharmacotherapy

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Published Papers (3 papers)

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Editorial

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3 pages, 152 KiB  
Editorial
Rare and Imported Infections: Are We Prepared?
by Godwin Oligbu
Pharmacy 2019, 7(1), 9; https://doi.org/10.3390/pharmacy7010009 - 13 Jan 2019
Cited by 1 | Viewed by 2474
Abstract
The world’s population is rapidly expanding [...] Full article
(This article belongs to the Special Issue Rare and Imported Paediatric Infections)

Review

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11 pages, 573 KiB  
Review
Risk of Transverse Myelitis Following Dengue Infection: A Systematic Review of the Literature
by Nafisa Badat, Dalia Abdulhussein, Peter Oligbu, Olakunle Ojubolamo and Godwin Oligbu
Pharmacy 2019, 7(1), 3; https://doi.org/10.3390/pharmacy7010003 - 23 Dec 2018
Cited by 10 | Viewed by 3948
Abstract
Introduction: Dengue virus (DENV) is one of the most common arbovirus diseases, with a wide spectrum of presentation. Spinal cord involvement in dengue infection (DF) is rare. However, the risk of transverse myelitis (TM) following Dengue has not been systematically assessed. Methods [...] Read more.
Introduction: Dengue virus (DENV) is one of the most common arbovirus diseases, with a wide spectrum of presentation. Spinal cord involvement in dengue infection (DF) is rare. However, the risk of transverse myelitis (TM) following Dengue has not been systematically assessed. Methods: We undertook a systematic review of published English literature from January 1974 to December 2017 to assess risk of TM and outcomes following DF. Data sources included EMBASE, MEDLINE, Cochrane library, ISI web of knowledge, conference proceedings and references within identified articles. Results: We identified 242 potential studies, 62 were duplicates. A further 136 were excluded on the basis of title and abstract and 19 studies did not meet the eligibility criteria on full text screening. We included 25 publications involving 2672 cases of DF. A small proportion (10.8%, (289/2672)) had neurological complications, of which 2.3% (61/2672) was TM. For articles reporting epidemiological data, the neurological complication was twice in males compared to female 67.7% (130/192) vs. 32.7% (62/192) and 1.5-fold increase TM for males 59.3% (32/54) vs 40.7% (22/54). The mean age at presentation was 33.1years (range 0.75–61), with onset at 11.7days. The method of diagnosing TM due to DF was mainly IgM seropositivity 92% (n = 23/25) and the commonest treatment modality was steroid 78.3% (n = 18/23). Only half had full recovery 50.8% (n = 31/61). There was no mortality following dengue, however, the crude case fatality rate following TM was 3.3% (n = 2/61). Conclusion: This review highlights the risk of TM following dengue. Although neurological complications are rare, especially TM, once set in, it is associated with a significant morbidity. Full article
(This article belongs to the Special Issue Rare and Imported Paediatric Infections)
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Other

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3 pages, 156 KiB  
Case Report
Teicoplanin-Induced Anaphylactic Reaction in Children: A Case Report
by Godwin Oligbu and Leila Ahmed
Pharmacy 2018, 6(4), 110; https://doi.org/10.3390/pharmacy6040110 - 9 Oct 2018
Cited by 1 | Viewed by 2886
Abstract
Teicoplanin is now increasingly used as a first-line prophylactic therapy for major surgical procedures, treatment of methicillin-resistant Staphylococcus aureus infections and for those with reported penicillin allergy. Teicoplanin is rarely associated with anaphylaxis and there is limited information on the prevalence of teicoplanin-induced [...] Read more.
Teicoplanin is now increasingly used as a first-line prophylactic therapy for major surgical procedures, treatment of methicillin-resistant Staphylococcus aureus infections and for those with reported penicillin allergy. Teicoplanin is rarely associated with anaphylaxis and there is limited information on the prevalence of teicoplanin-induced perioperative anaphylaxis. Here, we describe a case of a 12-year-old child with teicoplanin-induced anaphylaxis peri-operatively. Full article
(This article belongs to the Special Issue Rare and Imported Paediatric Infections)
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