Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine, 2nd Edition submission deadline 31 Jan 2026 | 4 articles | Viewed by 7911 | Submission Open
Keywords: drug development; therapeutic strategies; preclinical and clinical drug research; drug design; drug– drug interactions; clinical care; toxicological studies; disease risk; disease prognosis and response to therapy; biomarkers identification and application; biochemistry of drug uptake; action; and metabolism; drug target discovery; individualized therapy; pharmacogenomics; novel therapeutics; non-drug-related health interferences; nutritional interventions; chronobiology; medicinal chemistry; phytochemicals; biologics; personalized medicine; precision medicine
(This special issue belongs to the Section Clinical Pharmaceutics)
Nanomedicines for Overcoming Tumor Immunotherapy Tolerance
edited by Yaping Li
submission deadline 31 Jan 2026 | 5 articles | Viewed by 7326 | Submission Open
Keywords: tumor immunotherapy; immunotherapy tolerance; nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Controlled-Release Drug Delivery Systems for Anti-Inflammatory and Wound Healing Action
edited by , and Anica M. Petrović
submission deadline 31 Jan 2026 | 4 articles | Viewed by 4514 | Submission Open
Keywords: controlled drug delivery systems; systems for topical delivery; physicochemical characterization; stability studies; rheological properties; release and permeation testing; anti-inflammatory properties; wound-healing properties; natural products
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanoparticle-Based Gene Delivery
edited by Xiubo Zhao and
submission deadline 31 Jan 2026 | 3 articles | Viewed by 2696 | Submission Open
Keywords: nanaoparticles; gene delivery; nucleic acids; DNA; RNA; gene therapy
(This special issue belongs to the Section Gene and Cell Therapy)
Drug Formulation Design and Pharmacokinetics for the Treatment of Skin Diseases submission deadline 31 Jan 2026 | 2 articles | Viewed by 2454 | Submission Open
Keywords: pharmacokinetic studies of topical and transdermal therapies; advanced techniques for assessing drug penetration and distribution; optimization of therapeutic efficacy and safety profiles; dermatological drug delivery; topical formulations; skin pharmacokinetics; drug penetration; transdermal patches; creams and gels
(This special issue belongs to the Section Biopharmaceutics)
Biomedical Applications of Nanocarriers in Targeted Delivery of Bioactive Compounds submission deadline 31 Jan 2026 | 2 articles | Viewed by 2247 | Submission Open
Keywords: absorption; bioavailability; bioactive compounds; drug delivery systems; nanoencapsulation; nanomaterials; nanocarrier systems; natural compounds; oral administration; precision therapy; targeted delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Physiologically Based Pharmacokinetic (PBPK) Modeling and Applications
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 2184 | Submission Open
Keywords: physiologically based pharmacokinetic (PBPK) modeling; IVIVE; pharmacokinetics; ADME; modeling and simulation; PK/PD; biopharmaceutics; quantitative systems pharmacology
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Advances in Bioactive Compounds and Nanotechnology: Sustainable Approaches for Pharmaceutical Applications submission deadline 31 Jan 2026 | 3 articles | Viewed by 2129 | Submission Open
Keywords: natural bioactive compounds; biotechnological drug production; therapy; green cosmetics; eco-friendly pharmacy; natural preservatives; pharmaceutical formulation; nanomedicine; sustainability; green chemistry; green nanotechnology; sustainable drug delivery systems; controlled-release systems; nanocarriers for drug bioavailability; phytochemical-based drug therapies; lifecycle analysis of drug manufacturing; natural compounds in drug formulation; sustainable packaging for pharmaceuticals
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Integrating Phytocompounds with Nanotechnology: Revolutionary Approaches to Antimicrobial, Antioxidant, and Anti-Tumoral Therapies submission deadline 31 Jan 2026 | 3 articles | Viewed by 2010 | Submission Open
Keywords: bioactive phytocompounds  ; nanotechnology; nanomedicine; antimicrobial; antioxidant; anti-tumoral; drug delivery; plant-based therapeutics; phytochemical nanocarriers
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Synergistic Nanomedicines: Integrating Chemotherapy and Phototherapy for Enhanced Cancer Treatment
edited by Nasrin Hooshmand
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1848 | Submission Open
Keywords: nanomaterial; nanomedicine; chemo-photothermal therapy; cancer; drug delivery
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Drug Delivery, Diagnostics, and Therapeutics for Cancer: Toward Personalized Oncology
edited by , , Nelofer Syed and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1226 | Submission Open
Keywords: personalized medicine; cancer diagnostics; cancer therapeutics; cancer theranostics; radiotherapeutics; precision oncology; targeted therapy; immunotherapy; molecular diagnostics; biomarkers in cancer; cancer genomics; tumor microenvironment; surgical oncology; cancer biomarkers; AI in cancer diagnosis; multimodal cancer treatment; advanced imaging in oncology
(This special issue belongs to the Section Drug Delivery and Controlled Release)
CNS Drug Delivery: Recent Advances and Challenges
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1153 | Submission Open
Keywords: CNS drug delivery; blood– brain barrier; nanotechnology; targeted delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Drug Delivery Systems for the Management of Metabolic Diseases submission deadline 31 Jan 2026 | 1 articles | Viewed by 1016 | Submission Open
Keywords: drug delivery systems; metabolic diseases; nanotechnology; synthetic drugs and natural extracts; preclinical and clinical studies
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Antibacterial Nanoformulations Based on Natural Products
edited by , and Enrique Werner
submission deadline 31 Jan 2026 | 1 articles | Viewed by 948 | Submission Open
Keywords: nanoformulation; essential oil; extract; semisynthetic compound; hybrid compound; resinous exudate; antimicrobial agents; natural products
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Recent Advances in Nanotechnology-Based Approaches for Pharmaceutical Applications, 2nd Edition submission deadline 31 Jan 2026 | 1 articles | Viewed by 661 | Submission Open
Keywords: nanoparticles; drug delivery; biological barriers; pharmaceutical; diagnosis; therapy; efficacy and safety assessment; in vitro and in vivo studies
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Polymeric Materials and Drug Delivery Systems for Dental and Oral Health Applications submission deadline 31 Jan 2026 | 1 articles | Viewed by 535 | Submission Open
Keywords: prevention; dentistry; regeneration; drug delivery systems; antimicrobial properties; topical delivery; cancer therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Novel In Silico Supported Approaches for the Development and Delivery of Drugs for Antimicrobial Therapy and Neurodegenerative Diseases
edited by
submission deadline 31 Jan 2026 | Viewed by 363 | Submission Open
Keywords: antibacterials; antibiotics; chemotherapeutics; antivirals; antineurodegenerative; CADD; in silico drug design; drug delivery; in silico modeling; bioinformatics; machine learning; repurposing
(This special issue belongs to the Section Drug Targeting and Design)
Innovative Nano-Delivery Systems for Enhanced Oral Disease Therapies
edited by , and Elena Dinte
submission deadline 31 Jan 2026 | Viewed by 317 | Submission Open
Keywords: drug delivery systems; oral diseases; nanomaterials; nanoformulations; biomaterials; natural compounds
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Chemically Crosslinked Hydrogels at Different Scale Levels as Versatile Drug Delivery Systems in the Biomedical Field
edited by and Roberta Pappalardo
submission deadline 31 Jan 2026 | Viewed by 283 | Submission Open
Keywords: hydrogels; chemically crosslinked hydrogels; bulk hydrogels; macro-scale hydrogels; micro-scale hydrogels; nano-scale hydrogels; hydrogel-based drug delivery systems; advanced therapies
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Drug Delivery Systems for Leishmaniasis Therapy
edited by Elizabeth Igne Ferreira, Jeanine Giarolla and Soraya Da Silva Santos
submission deadline 31 Jan 2026 | Viewed by 225 | Submission Open
Keywords: delivery systems; leishmanicides; bioactive compounds in Leishmania sp.; advanced systems for drug delivery; oral and topical administration
(This special issue belongs to the Section Drug Targeting and Design)
Advances in Inhalation Formulations: Innovations and Analytical Approaches for Pulmonary and Nasal Drug Delivery
edited by Helvécio Vinicius Antunes Rocha and
submission deadline 31 Jan 2026 | Viewed by 220 | Submission Open
Keywords: inhalation formulation; pulmonary delivery; nasal delivery
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Inflammation-Targeted Nanomedicines for the Treatment of Chronic Inflammatory Diseases and Cancer
edited by and
submission deadline 31 Jan 2026 | Viewed by 129 | Submission Open
Keywords: Alzheimer’ s disease; atherosclerosis; cancer; chronic inflammation; chronic respiratory diseases; diabetes; immunomodulation; inflammation-responsive drug delivery systems; inflammatory bowel disease; multiple sclerosis; nanomedicine; novel biomaterials; rheumatoid arthritis; targeted drug delivery
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Functional Nanomaterials in Pharmaceutical and Biomedical Applications submission deadline 31 Jan 2026 | Viewed by 76 | Submission Open
Keywords: nanomaterials; drug delivery; bioimaging; tissue engineering; gene transfection; hyperthermic therapies; photodynamic therapies; photoacoustic therapies
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Emerging Trends in Smart Theranostic Nanomedicine
edited by , and Thavasyappan Thambi
submission deadline 31 Jan 2026 | Viewed by 64 | Submission Open
Keywords: various types of nanoparticles; smart nanomaterials; theranostic agents; diagnostics; synthesis and characterization; drug delivery system; in vitro and in vivo studies; synergistic therapy; cancer therapy; microbial infections; multimodal imaging; theranostics; tumor and microbial targeting
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Bio-Based Materials and Personalized Medicine: Innovative Applications in Tissue Engineering and Drug Delivery submission deadline 31 Jan 2026 | Viewed by 63 | Submission Open
Keywords: bio-based materials; biocompatibility; sustainability; extracellular matrix; customized scaffolds; drug delivery; controlled drug delivery systems; tissue engineering; tissue regeneration; personalized medicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advanced Theranostic Nanoplatforms for Precision Therapy
edited by and Secheol Oh
submission deadline 31 Jan 2026 | Viewed by 57 | Submission Open
Keywords: theranostic nanoplatforms; extracellular vesicles (EVs); targeted drug delivery; stimuli-responsive nanomaterials; antimicrobials; cancer and infectious disease therapy; nanomedicine; biocompatible nanomaterials; real-time imaging; modular nanostructures; precision medicine; bacterial ghost
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Delivery Systems for Antidiabetic Drugs and Beyond Glycaemic Control submission deadline 31 Jan 2026 | Viewed by 36 | Submission Open
Keywords: diabetes; biopolymers; patches; nanocarriers; inserts; pharmacokinetics; diagnostics; devices
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanoparticles for Dermal and Transdermal Delivery
edited by Nina Dragićević
submission deadline 31 Jan 2026 | Viewed by 34 | Submission Open
Keywords: nanoparticles; nanocarriers; lipid-based nanoparticles; polymeric nanoparticles; metallic nanoparticles; dermal delivery; transdermal delivery; skin permeation; drug delivery systems
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovations in Preclinical Drug Development: Efficacy, Safety, and Translational Strategies
edited by Xi Xu and Hongxi Wu
submission deadline 31 Jan 2026 | Viewed by 28 | Submission Open
Keywords: preclinical drug development; drug design; advanced disease models; three Rs principles; molecular glue degrader; antibody-drug conjugate; glutamine metabolism
(This special issue belongs to the Section Drug Targeting and Design)
Emerging Strategies to Enhance Solubility of Poorly Soluble Drugs: From Nanosystems to Molecular Innovations submission deadline 31 Jan 2026 | Viewed by 25 | Submission Open
Keywords: poorly soluble drugs; solubility enhancement; nanotechnology; amorphous solid dispersions; cyclodextrin complexation; co-crystallization; ionic liquids; deep eutectic solvents; prodrug design; formulation technologies
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Dendrimer-Mediated Drug, Gene, and Protein Delivery for Disease Treatment submission deadline 31 Jan 2026 | Viewed by 22 | Submission Open
Keywords: dendrimers; drug delivery; gene delivery; protein delivery; targeted therapy; bioconjugation; controlled release; tumor therapy; inflammatory diseases; infectious diseases
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Recent Advances in Metal-Based Drug Delivery Systems for Cancer Therapy submission deadline 31 Jan 2026 | Viewed by 18 | Submission Open
Keywords: metal-based drug delivery systems; cancer therapy; stimuli-responsive prodrugs; nanomedicine; coordination complexes; targeted chemotherapy
(This special issue belongs to the Section Drug Targeting and Design)
Advanced Metal-Based Nano-Drug Delivery Systems for Antimicrobial Therapy
edited by
submission deadline 31 Jan 2026 | Viewed by 16 | Submission Open
Keywords: nanosystems; micelles; liposomes; nanoparticles; metal-based drugs; drug delivery; antimicrobial therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Pharmaceutical Applications of Therapeutic Deep Eutectic Systems (THEDES) submission deadline 31 Jan 2026 | Viewed by 15 | Submission Open
Keywords: eutectic systems; therapeutic deep eutectic systems; natural deep eutectic systems; biomedicine; drug delivery systems; bioavailability; antimicrobial; cancer; anti-inflammatory; antioxidant
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Prodrug Applications for Targeted Cancer Therapy
edited by René C.-Gaudreault and Atziri Corin Chavez Alvarez
submission deadline 31 Jan 2026 | Viewed by 14 | Submission Open
Keywords: anticancer agents; prodrugs; targeted cancer therapy; precision medicine; translational oncology; structure– activity relationship; clinical oncology
(This special issue belongs to the Section Drug Targeting and Design)
Targeted Drug Delivery Strategies for Infectious Diseases
edited by Danielle Lazarin Bidóia, Daniele Stéfanie Sara Lopes Lera-Nonose and Áquila Carolina Fernandes Herculano Ramos Milaré
submission deadline 31 Jan 2026 | Viewed by 11 | Submission Open
Keywords: infectious disease; treatment; delivery system; biomaterial; targeted drug therapy; liposome; dendrimer; nanotube; nanotechnology; formulation; polymer; antifungal; antimicrobial; antiparasitic; antibiotic; vaccine; bacterial infection; adjuvant; antiviral; biofilm-related infection; bacteria; antiparasitic
(This special issue belongs to the Section Drug Targeting and Design)
Microfluidic Devices for Encapsulating and Delivering Large Biomolecules
edited by , Hema Choudhary and Sheng Zhao
submission deadline 31 Jan 2026 | Viewed by 10 | Submission Open
Keywords: microfluidics; lipid nanoparticles; biohybrid and biomimetic nanoparticles; nucleic acid delivery; delivery vectors; microfluidic mixing; droplet microfluidics; protein delivery; encapsulation; vaccine development; microgels; single-cell sequencing; biomolecules
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Lipid-Based Nanoparticulate Drug Delivery Systems: Preparation, Biomedical Applications, and Evaluation, 2nd Edition submission deadline 31 Jan 2026 | Viewed by 6 | Submission Open
Keywords: liposomes; nanoemulsions; nanostructured lipid carriers; niosomes; solid lipid nanoparticles; targeted drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Magnetic Nanoparticles in Regenerative Medicine and Tissue Engineering
edited by Mauricio César De Marzi and
submission deadline 31 Jan 2026 | Viewed by 6 | Submission Open
Keywords: magnetic nanoparticles; regenerative medicine; tissue engineering; targeted drug delivery; magnetically responsive scaffolds
Molecular Strategies to Enhance Drug Solubility submission deadline 31 Jan 2026 | Viewed by 3 | Submission Open
Keywords: drug solubility; molecular strategies; co-crystals; amorphous solid dispersions; co-amorphous systems; salt formation; prodrugs; molecular complexation; solubility enhancement; pharmaceutical formulation
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advances in Pharmaceutics, Genomics, and Biotechnology for Liver Disease Therapy submission deadline 31 Jan 2026 | Viewed by 2 | Submission Open
Keywords: liver disease; nanocarriers; lipid nanoparticles; gene therapy; bioengineered scaffolds; biotechnological innovation; drug delivery; pharmaceutical formulation
(This special issue belongs to the Section Drug Targeting and Design)
Multifunctional Natural Polymer-Based Therapeutic Systems: Drug Delivery Meets Tissue Engineering submission deadline 10 Feb 2026 | Viewed by 82 | Submission Open
Keywords: natural polymers; multifunctional biomaterials; drug delivery systems; tissue engineering; hydrogels; polymeric scaffolds; three-dimensional bioprinting; controlled release; biomimetic polymeric biomaterials; regenerative medicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Stability of Medicines and Novel Approaches for Predicting Drug Stability submission deadline 20 Feb 2026 | 10 articles | Viewed by 49643 | Submission Open
Keywords: stability; 3D printing; ICH; physical stability; biologicals
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Recent Advances in the Development, Characterization, and Stability Aspects of RNA-Based Vaccines
edited by and
submission deadline 20 Feb 2026 | 1 articles | Viewed by 2721 | Submission Open
Keywords: RNA-based vaccines; lyophilization; stability; gene therapy; formulation strategies; novel characterization; delivery systems; biopharmaceuticals; continuous manufacturing; AI/ML/digital twin
(This special issue belongs to the Section Gene and Cell Therapy)
Extracellular Vesicle for Drug Delivery
edited by
submission deadline 20 Feb 2026 | 1 articles | Viewed by 807 | Submission Open
Keywords: estracellular vesicle; exosomes; drug delivery; behavior; uptake; quantification; controlled release
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Functionalized Polymers for Anticancer Applications
edited by Alejandro Ramirez-Jimenez, and Alexei Fedorovish Licea-Navarro
submission deadline 20 Feb 2026 | Viewed by 432 | Submission Open
Keywords: photodynamic therapy; photothermal therapy; sonodynamic therapy; immunotherapy; smart polymeric nanocarriers; specific drug delivery; functionalized polymers; anticancer drug delivery; metallodrugs; theragnostic
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Drug Delivery Carriers for Anticancer Therapy
edited by
submission deadline 20 Feb 2026 | Viewed by 75 | Submission Open
Keywords: drug delivery systems; cancer therapy; nanoparticles; tumor targeting; controlled release; theranostics; liposomes; protein nanocarriers; polymeric micelles
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Understanding Drug Disposition: The Interplay of Absorption, Distribution, and Excretion Processes, and Transport Mechanisms
edited by , and Carolina Inés Ghanem
submission deadline 20 Feb 2026 | Viewed by 40 | Submission Open
Keywords: transporters; drug disposition; absorption; drug interactions; drug therapy; pharmacokinetics; bioavailability; multidrug resistance
(This special issue belongs to the Section Biopharmaceutics)
Multifunctional Drug Delivery Systems
edited by
submission deadline 20 Feb 2026 | Viewed by 16 | Submission Open
Keywords: multifunctional delivery systems; nanoparticles; targeting delivery; immune-modulating delivery systems; nanoparticle conjugation; sustained drug release; smart polymers; polysaccharide-based carriers; smart nanocarrier systems
(This special issue belongs to the Section Drug Delivery and Controlled Release)
A Commemorative Issue in Honor of Professor Gregory Gregoriadis: Liposomes for the Delivery of Drugs and Vaccines submission deadline 28 Feb 2026 | 7 articles | Viewed by 26371 | Submission Open
Keywords: liposomes for drug delivery (for therapy of cancer; infectious diseases; neurodegenerative diseases; etc.); development; applications; and challenges of ligand-targeted liposomal drugs; liposomes and biological barriers; liposomes as immunological adjuvants; cationic liposomes and lipid nanoparticles as vaccine carriers; immunization with nucleic acids in liposomes; entrapment of nucleic acid vaccines in cationic liposomes
(This special issue belongs to the Section Physical Pharmacy and Formulation)
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