Translating Phytochemicals into Clinical Pharmaceutics: Advances in Bioactive Compounds, Formulations, and Therapeutic Applications

Dear Colleagues,

Phytochemicals and bioactive compounds from medicinal plants have long been a cornerstone of traditional medicine and continue to inspire modern drug discovery. However, their clinical translation faces numerous challenges, including poor solubility, instability, limited bioavailability, and a lack of standardized formulations. Recent advancements in clinical pharmaceutics—encompassing novel delivery systems, pharmacokinetic modeling, and personalized approaches—are now bridging these gaps and enhancing the therapeutic potential of natural products. This Special Issue aims to gather cutting-edge research and reviews focused on the pharmaceutical development, clinical evaluation, and therapeutic optimization of phytochemicals and plant-derived bioactive compounds. By emphasizing formulation strategies, biopharmaceutical characterization, and clinical outcomes, this Special Issue will highlight the evolving role of natural compounds in modern therapeutics and their integration into evidence-based clinical pharmaceutics.

Dr. Lucas Fornari Laurindo
Guest Editor

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