Special Issue "Gut Microbiome"
A special issue of Pathogens (ISSN 2076-0817).
Deadline for manuscript submissions: closed (1 March 2014).
Interests: Helicobacter pylori; host-pathogen interactions in gastrointestinal tract; infection and gastrointestinal cancer; mucosal immunology
Special Issues and Collections in MDPI journals
Special Issue in Toxins: H. pylori Virulence Factors in the Induction of Gastric Cancer
Interests: role of Gut microbiota in health and disease; Helicobacter pylori associated diseases; Population-based epidemiological studies of the gut system
Advances in metagenomics and bioinformatics are pioneering our understanding of the gut microbiota in health and disease. Phylum level differences in gut microbiota occur in many clinical conditions bringing the opportunity that manipulation of the gut microbiome may be a way to impact on multiple diseases. The gut microbiome can modify human physiology influencing nutrient extraction from dietary intake and effect gut mucosal immune responses contributing to both the maturation of the gut immune system as well as autoimmune diseases. The Human Microbiome Project has identified the normal gut microbiome in individuals in developed countries. There is little data on the normal human gut microbiome in developing countries and the impact of global dietary variations. Exciting recent data indicate that the gut microbiome can contribute to both malnutrition and obesity and that exposure to antibiotics early in life can lead to increased adiposity. Also, antibiotic overuse will kill beneficial bacteria. Diet impacts on the composition of the gut microbiome opening the opportunity for therapeutic dietary manipulation of gut microbiota. We look forward to your contributions and to a valuable edition that will promote further developments in this exciting field.Thank you for your collaboration.
Prof. Dr. Jean E. Crabtree
Prof. Dr. Lars Engstrand
Manuscript Submission Information
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