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Precision Nutrition & Food Security in the Digital Era. Nutrigenetics & Nutrition during the Life Cycle

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 1928

Special Issue Editors

Prof. Dr. Doina Drǎgǎnescu
E-Mail Website
Guest Editor
Department of Pharmaceutical Physics and Informatics, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 020956 Bucharest, Romania
Interests: pharmaceutics and pharmaceutical technology; pharmaceutical research and development; dosage form development; pharmaceutical industry; pharmaceutical analysis; preformulation studiesthree-dimensional printing
Special Issues, Collections and Topics in MDPI journals
Department of Pharmaceutical Microbiology, Faculty of Pharmacy, University of Medicine and Pharmacy “Carol Davila”, 020956 Bucharest, Romania
Interests: drug-resistance mechanisms of various microorganisms; antimicrobial properties of phytopharmaceutical formulations with standardized herbal extracts; antimicrobial properties of newly synthesized biochemicals; microbiological contamination of drugs; pathophysiological implications of the human microbiota; biologics and biosimilars; drug development and analysis; drug interactions; drug metabolism
Special Issues, Collections and Topics in MDPI journals
Department of Clinical Laboratory and Food Safety, Faculty of Pharmacy, University of Medicine and Pharmacy “Carol Davila”, 020956 Bucharest, Romania
Interests: drug development and analysis; biochemical mechanisms of drugs; clinical biochemistry; drug–food interactions; clinical pharmacology
Special Issues, Collections and Topics in MDPI journals
Department of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 020956 Bucharest, Romania
Interests: pharmaceutical development; solid oral forms; modified release; drug formulation; food supplement formulation; food and drug regulatory affairs; pharmacovigilance; human nutrition research; energy metabolism; molecular nutrition;vitamins; lipid metabolism
Special Issues, Collections and Topics in MDPI journals
Department of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 020956 Bucharest, Romania
Interests: drug design; development, optimization, and manufacturing of pharmaceutical products; pre- and post-compression parameters for solid dosage forms; preformulating studies on pharmaceuticals; physico-chemical characterization of materials; cyclodextrin inclusion complexes; drug delivery systems; pharmaceutical processes; drug release profiles; quality of pharmaceutical forms
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, the general trend has been to pay increasing attention towards nutrition and health status, which is often assessed throughout the life cycle. Scientists' concerns are directed towards diverse topics such as food consumption and specific nutrients, critical micronutrients (e.g., iodine, folate, vitamin D), food quality and food safety, dietary patterns and related trends, sustainable diets and food organic foods, reducing food waste, diet in Nordic countries, progress made in studying various food patterns, medical nutrition, impact of nutrition on immune function, and early intervention in lifestyle, all which have a major impact on preventing and treating chronic diseases.

Cardio-metabolic diseases, such as overweight and obesity, cardiovascular diseases, stroke, type 2 diabetes, metabolic syndrome, liver diseases, and various types of cancer are the main causes of mortality and disability worldwide. It is true that genetic and environmental factors play a role in increasing the risk of these diseases. However, eating behavior and lifestyle are determining factors involved in the occurrence of the non-communicable diseases listed above. Additionally, the good news is that lifestyle and eating habits are modifiable factors. Moreover, the risk for the occurrence of cardiovascular diseases derives from intrauterine life. Additionally, the eating habits formed in the first years of life have a major impact on health in adulthood. This therefore becomes a legitimate concern related to eating habits and lifestyle, both at the global, regional, and national level, but especially at the individual level.

Additionally, in recent decades, nutritional research has shifted its focus from the effects of individual foods and nutrients to the study of dietary patterns, assuming that certain food/nutrient combinations may have synergistic/antagonistic effects compared to individual elements.

Modern nutritional theories are based on nutritional genetics, which studies the molecular genetic mechanisms through which diet predisposes to chronic diseases and premature aging through its two branches: nutrigenetics and nutrigenomics.

In this Special Issue, theoretical and experimental contributions as full-length original research articles, literature reviews, and short communications are welcome to be submitted.

We welcome and look forward to your submissions.

Prof. Dr. Doina Drǎgǎnescu
Prof. Dr. Andreea Letitia Arsene
Dr. Magdalena Mititelu
Dr. Denisa Udeanu
Dr. Anca Lucia Pop
Dr. Emma Adriana Ozon
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • precision nutrition
  • nutritional evaluation
  • food safety
  • fighting hunger
  • nutritional professionals
  • dietetics
  • food supplements
  • functional food
  • oral and gastrointestinal microbiota

Published Papers (1 paper)

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Research

27 pages, 7613 KiB  
Article
Safety of Innovative Nanotechnology Oral Formulations Loaded with Bioactive Menopause Molecules: Influence of Genotoxicity and Biochemical Parameters on a Menopausal Rat Model
Nutrients 2023, 15(23), 4951; https://doi.org/10.3390/nu15234951 - 29 Nov 2023
Cited by 1 | Viewed by 1257
Abstract
In recent years, nanoparticles have gained significant importance due to their unique properties, such as pharmacological, electrical, optical, and magnetic abilities, contributing to the growth of the science and technology sector. Particular naturally derived biomolecules with beneficial effects on menopause disorder have been [...] Read more.
In recent years, nanoparticles have gained significant importance due to their unique properties, such as pharmacological, electrical, optical, and magnetic abilities, contributing to the growth of the science and technology sector. Particular naturally derived biomolecules with beneficial effects on menopause disorder have been the subject of studies of pharmaceutical formulation to obtain alternative pharmaceutical forms with increased bioavailability and without side effects, as in nanostructured lipid carriers (NLCs) loaded with such active ingredients. In the present study, one stage of a broader project, we have performed pharmacotoxicology studies for six combinatory innovative nanocapsule pharmaceutical forms containing active natural biomolecules before considering them as oral formulas for (1) in vitro toxicity studies on culture cells and (2) in vivo preclinical studies on a surgically induced menopause model of Wistar female rats, and the influence of the NLCs on key biochemical parameters: lipid profile (TG, Chol, HDL), glycemic markers (Gli), bone markers (Pac, Palc, Ca, phosphorus), renal markers (Crea, urea, URAC), inflammation (TNF), oxidative stress (GSH, MDA), and estrogen–progesterone hormonal profile. The micronucleus test did not reveal the genotoxicity of the tested compounds; the menopause model showed no significant safety concerns for the six tested formulas evaluated using the blood biochemical parameters; and the results showed the potential hypoglycemic, hypolipidemic, hypouricemic, and antioxidant potential of one of the tested formulas containing nano diosgenin and glycyrrhizic acid. Full article
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