Recent Advancements in Ageing Research: From Molecular Basis to Clinical Outcomes
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Biochemistry, Molecular and Cellular Biology".
Deadline for manuscript submissions: closed (7 April 2025) | Viewed by 68
Special Issue Editor
Interests: prebiotics; probiotics; microbiota; microbiology control; infectious contaminants; food safety
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Special Issue Information
Dear Colleagues,
Ageing is a complex biological process driven by a network of interconnected molecular mechanisms that influence cellular homeostasis, tissue function, and overall organismal health. Over the past few decades, significant progress has been made in understanding the molecular underpinnings of ageing, particularly in relation to the 12 hallmarks of ageing, which include genomic instability, telomere attrition, epigenetic alterations, mitochondrial dysfunction, and altered intercellular communication. These mechanisms shape the ageing trajectory and contribute to the onset of age-related diseases, making them prime targets for therapeutic intervention. Recent advancements in molecular biology and translational research have led to the identification of novel biomarkers and potential interventions that could mitigate the effects of ageing and enhance longevity.
For this Special Issue of Current Issues in Molecular Biology, we invite the submission of high-quality original research articles and comprehensive reviews that explore recent developments in ageing research. We welcome contributions that delve into the molecular and cellular mechanisms of ageing, the role of telomere biology, the interplay between ageing hallmarks, and their implications in clinical practice. Studies on novel biomarkers, therapeutic strategies, and translational applications in ageing-related disorders are particularly encouraged.
This Special Issue reflects the valuable contributions of MPharm Miruna-Maria Apetroaei from Carol Davila University of Medicine and Pharmacy, Romania, who serves as Assistant Guest Editor, playing a key role in supporting its editorial management and coordination.
We also extend our gratitude to Acad. Dr. Aristides M. Tsatsakis from the University of Crete, Greece, for his vision in conceptualizing this Special Issue, fostering collaboration, and providing essential oversight throughout its development.
Prof. Dr. Andreea Letitia Arsene
Guest Editor
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Keywords
- telomere biology
- telomere length
- genomic instability
- epigenetic alterations
- DNA damage response
- mitochondrial dysfunction
- cellular senescence
- proteostasis
- stem cell exhaustion
- inflammaging
- altered intercellular communication
- metabolic deregulation
- age-related biomarkers
- longevity interventions
- senotherapeutics
- age-related diseases
- translational geroscience
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