Journal Menu► ▼ Journal Menu
Journal Browser► ▼ Journal Browser
Special Issue "Nutrition and Apoptosis"
A special issue of Nutrients (ISSN 2072-6643).
Deadline for manuscript submissions: 31 March 2020.
Prof. Paola Rizzo
University of Ferrara, Department of Morphology, Surgery and Experimental MedicineVia Fossato di Mortara 64/b 44121—Ferrara, Italy and GVM Care and Research, Maria Cecilia Hospital, Cotignola, Italy
Several bioactive compounds and nutrients in foods and food by-products have physiological properties that are beneficial for human health. Indeed, agricultural and food waste management is a great challenge for global security and environmental governance, directly linked with global competitiveness, increasing population, and other economic related factors. Under the European 2020 growth strategy launched in 2010, Europe has set itself the goal of shifting from linear to circular models of production and consumption. This important issue needs advanced efficient alternatives other that landfilling or composting, in order to maximize the value derived from such an important waste source. The food waste, including both edible food and inedible parts, has been estimated in Europe to be 88 million tonnes (9 million tonnes comes from primary production), costing around 143 billion euros.
In the last decade, increasing attention has been devoted to the recycling of functional ingredients from fruit and vegetable by-products. From the perspective of bio sustainable development and renewable resource technologies, by-products and waste represent a relatively cheap source of material suitable for bioactive molecules production, which would reduce both the amount of waste and the related costs of disposal, while producing added-value nutritional products. While nutrients typically have a clear definition with established levels of recommended intakes, bioactive compounds lack such a definition. There is well-established evidence of the pharmacological properties of these bioactive compounds that render them therapeutically effective in chronic inflammatory diseases such as cardiovascular disease, Crohn, and IBD. In addition, a large amount of information in the literature confirms that nutraceuticals have chemopreventive activity, as suggested by epidemiologic and animal model studies. Their ability to reduce cancer incidence in these studies is likely related to apoptosis.
In this Special Issue, we invite investigators to contribute original research articles reporting data from both experimental and clinical studies, as well as review articles, that provide a better understanding of the effects of nutraceuticals and phytochemicals on cardiometabolic disorders, inflammatory intestinal diseases, and cancer linked to apoptosis, as well as their applications in cosmetic field. Since there has recently been great social and environmental interest in the efficient reuse of agriculture waste co- and by-products, which are often rich in bioactive compounds, papers related to the identification and recovery of such compounds are also encouraged.
Potential topics include but are not limited to the following:
- The evaluation of the potential of using nutraceuticals as chemopreventive reagents, or in cardiometabolic and intestinal disorders, or in cosmetic field, by in vitro and in vivo (including studies in human) studies, including the safety, cellular, and molecular mechanisms underlying apoptosis. 3D cell models will also be accepted.
- High-performance analytical methods suitable for the extraction and purification of the natural compounds from functional foods, dietary supplements, and herbs, for their stability and the study of the bioavailability in vitro and/or in vivo in biological fluids;
- Bioanalytical methods to determine the biological and toxicological effects of these substances and their effect on the management of cancer and cardiometabolic and intestinal disorders, and in the cosmetic field;
- The study of the physico- chemical properties of these compounds to develop new formulations that help in ameliorating oxidative stress-induced inflammatory diseases (such as Irritable Bowel Syndrome (IBD) and atheroscelosis)
Dr. Cristiana Caliceti
Prof. Paola Rizzo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Bioactive molecules
- Endothelial function
- Dietary compounds
- Food byproducts
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.