Special Issue "Metabolomics in Nutrition and Human Health"
Deadline for manuscript submissions: closed (30 September 2020).
Interests: nutrition; metabolism; nutrimetabolomics; metabolic diseases; physiology
Interests: nutrimetabolomics; biomarkers; food metabolome; metabotypes; Mediterranean diet; dietary patterns; intervariability; cardiovascular diseases; age-related diseases; intestinal microbiota
Metabolomics can be defined as the global analysis of all low molecular weight compounds in a biological sample, for example, biofluids (blood, urine, saliva, bile or cerebrospinal fluid), cellular extracts or tissues. These small molecules (<1500 Da) are the result of normal metabolism but can also be produced under the influence of external stimuli, such as dietary interventions, environmental factors or drugs.
The integration of metabolomics with nutritional science enhances current clinical and research practices by providing a deeper insight into the relationships between various metabolites and health status. In recent years, metabolomics has been used to assess nutritional status and facilitate the discovery of new biomarkers associated with specific nutrients (food metabolome) or forms of metabolic dysfunction.
Nutritional metabolomics provides better and more individualized biomarkers than most other techniques and is expected to give better indicators of the dietary effects on a target population or patients. Metabolomics has enabled the evolution of clinical research from a rather reductionist approach towards an integrative strategy. It has also provided a new way to analyse the effects of diet from genes to metabolites, giving unique insights into mechanisms underlying the development of chronic metabolic diseases, leading to comprehensive phenotyping and metabotyping of individuals on precise nutrition parameters and determining biomarkers for the early diagnosis of risk (screening biomarkers). Other biomarkers can also assist in the care of patients with suspected disease (diagnosis biomarkers) or with progression or remission of disease (prognostic biomarkers).
The purpose of this Special Issue is to expand and add to the research on the importance of metabolomic study related to human nutrition and nutrition-related disorders (obesity, metabolic syndrome, insulin resistance). Submissions may include studies focused on nutritional metabolomics aimed at investigating perturbations of the metabolome by specific diets, dietary patterns, foods, nutrients, microorganisms, or bioactive compounds and research into biomarkers linked to such perturbations. This issue welcomes the submission of manuscripts describing related original research or reviews of the scientific literature in humans (interventional, observational, cohort studies) or animal models.
Dr. Sergio Polakof
Dr. Mireia Urpi-Sarda
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- dietary-related diseases
- food metabolome
- animal models