Nanomaterials in Biological Systems: Opportunities and Challenges
A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".
Deadline for manuscript submissions: closed (20 January 2024) | Viewed by 32621
Special Issue Editors
Interests: biocompatibility; in vitro/in vivo cytotoxicity; in vivo interactions; hyperthermia
Special Issue Information
Dear Colleagues,
Nanomaterials are a class of materials with unique properties that can be used in a wide range of applications and improve biomedical treatments. The different types of nanomaterials (inorganic and polymeric nanoparticles, liposomes, nanocrystals, nanotubes, dendrimers) can be specifically designed and functionalized to become biocompatible and to serve a specific a biomedical purpose. Numerous nanomaterials are being developed and studied for many applications, such as drug delivery, hyperthermia, imaging agents for diagnosis, and treatment of several conditions. Nanomaterials enable creating new therapeutic approaches and optimizing conventional treatments as they allow the delivery of drugs to the affected organ/tissue in a more specific and controlled way, as well as stimuli-responsive therapeutics. These features facilitate the use of lower doses and promote local rather than systemic action, avoiding or reducing side effects. Nanostructured materials also allow the development of treatments based on hyperthermia, such as thermocytolysis and thermoablation. Nonetheless, while nanomaterials present many potential advantages and open several opportunities for new biomedical and theragnostic applications, their interaction with biological systems still poses several challenges. Their short- and long-term effects on different cell types, organs, and body systems still need to be better understood.
The aim of this Special Issue is to explore the applications of nanostructured materials for biological and/or biomedical applications and the interactivity of these materials with different cells, organs, and biological systems.
Prof. Dr. Carolina Madeira Lucci
Prof. Dr. Ricardo Bentes Azevedo
Guest Editors
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Keywords
- nanostructured materials
- biomedical applications
- biocompatibility
- in vitro/in vivo cytotoxicity
- in vivo interactions
- pharmacokinetics
- clearance in complex biological systems
- theragnostic
- nanomedicine
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