Special Issue "Synthesis and Application of Nanomaterials in Medicine and Related Sciences"

A special issue of Nanomaterials (ISSN 2079-4991).

Deadline for manuscript submissions: 31 March 2020

Special Issue Editors

Guest Editor
Prof. Dr. Pawel Pohl

Faculty of Chemistry, Division of Analytical Chemistry and Chemical Metallurgy, Wroclaw University of Science and Technology, Wroclaw, Poland
Website | E-Mail
Interests: hyphenation of chromatographic separation and pre-concentration techniques (LC, HPLC, CE, SPE) with spectrometric methods of detection (ICP-OES, ICP-MS, FAAS, ETAAS, MS/MS) for speciation and fractionation analysis of metals and metalloids; development and application of chemical vapor generation (CVG) techniques for analytical atomic and mass spectrometry; analytical and spectroscopic characteristics of cold atmospheric pressure plasmas (CAPPs); application of CAPPs in biology, medicine and technology
Guest Editor
Dr. Piotr Jamroz

Faculty of Chemistry, Division of Analytical Chemistry and Chemical Metallurgy, Wroclaw University of Science and Technology, Department of Chemistry, Wroclaw, Poland
Website | E-Mail
Interests: cold atmospheric pressure plasmas (CAPPs); analytical chemistry; nanotechnology; plasma medicine; plasma spectroscopy; analytical atomic spectrometry; microplasmas, materials engineering
Guest Editor
Dr. Anna Dzimitrowicz

Faculty of Chemistry, Division of Analytical Chemistry and Chemical Metallurgy, Wrocław University of Science and Technology, Wroclaw, Poland
Website | E-Mail
Interests: cold atmospheric pressure plasmas (CAPPs); electrotechnics, glow discharge (GD); microbiology; nanomaterials; nanotechnology; plasma medicine; toxicity of nanomaterials; impact of nanomaterials on environment

Special Issue Information

Dear Colleagues,

The development of synthesis methods of various organic and inorganic nanomaterials, which differ due to morphology, functionality, toxicity, stability, and biological properties, certainly opens a broad route to their practical and innovative applications in medicine and related sciences such as clinical diagnostics and therapies, biomedical analyses, and pharmacology. Their small size and optical properties, and the possibility of surface modification, make different nanomaterials, including nanoparticles, quantum dots, as well as carbon based nanostructures, especially applicable in anticancer therapy, drug delivery systems, bioimaging of cells and tissues, and regeneration of tissues and organs. The unique spectroscopic properties of certain nanomaterials and their specific responses in the presence of biological substances make them very useful for the production of electrodes or sensors used for their detection and monitoring. Finally, some nanomaterials exhibit antimicrobial activity; hence, they can be applied for alternative antimicrobial therapies and treatment.

The present Special Issue is dedicated to all researchers and academics who deal with the synthesis, characterization, and practical applications of nanomaterials in new medical therapies, diagnostics, and analyses due to their biological activity with therapeutic relevance and other desirable physicochemical properties. Basic research aimed at elucidating mechanisms of action of these nanomaterials are also of interest for this Issue.

Prof. Dr. Pawel Pohl
Dr. Piotr Jamroz
Dr. Anna Dzimitrowicz
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Nanomedicine
  • Anti-cancer therapy
  • Anti microbial therapy
  • Regenerative medicine
  • Disease detection
  • Cancer detection
  • Drug delivery systems
  • Magnetic and fluorescence imaging contrast agents
  • Sensing and monitoring of biological substances.

Published Papers (1 paper)

View options order results:
result details:
Displaying articles 1-1
Export citation of selected articles as:

Research

Open AccessArticle Microstructured and Degradable Bacterial Cellulose–Gelatin Composite Membranes: Mineralization Aspects and Biomedical Relevance
Nanomaterials 2019, 9(2), 303; https://doi.org/10.3390/nano9020303
Received: 28 January 2019 / Revised: 13 February 2019 / Accepted: 14 February 2019 / Published: 22 February 2019
PDF Full-text (6702 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
Bacterial cellulose (BC)–gelatin (GEL) membranes were processed by successive periodate oxidation and a freeze-thawing/carbodiimide crosslinking procedure, first facilitating a Schiff-base reaction among respective aldehyde and hydroxyl groups, and later GEL stabilization and microstructuring. The formation of highly microporous structures within the GEL portion, [...] Read more.
Bacterial cellulose (BC)–gelatin (GEL) membranes were processed by successive periodate oxidation and a freeze-thawing/carbodiimide crosslinking procedure, first facilitating a Schiff-base reaction among respective aldehyde and hydroxyl groups, and later GEL stabilization and microstructuring. The formation of highly microporous structures within the GEL portion, with significant differences between bottom and top, was elucidated, and pores in the 27.6 ± 3 µm–108 ± 5 µm range were generated, exceeding the threshold value of ~10 µm sufficient for cell trafficking. During a relatively short (6 h) exhaustion procedure in supersaturated simulated body fluid solution, the membranes accommodated the combination of biologically relevant minerals, i.e., flake-like octacalcium phosphate (OCP) and (amorphous) apatite, onto their surface, forming a membrane with intensive swelling (650–1650%) and up to 90% weight loss in a 4-week period. The membranes´ 6-day eluates did not evoke any cytotoxic effects toward human fibroblast, MRC-5 cells. The same type of cells retained their morphology in direct contact with the membrane, attaching to the GEL porous site, while not attaching to the GEL thin-coated BC side, most probably due to combined, ablation effect of dominant β-sheet conformation and carbodiimide crosslinking. Together with arrested proliferation through the BC side, the membranes demonstrated beneficial properties for potential guided tissue regeneration (GTR) applications. Full article
Figures

Graphical abstract

Nanomaterials EISSN 2079-4991 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top