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Environmental Analysis of Organic Pollutants, 3rd Edition

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Green Chemistry".

Deadline for manuscript submissions: 31 May 2027 | Viewed by 678

Editor


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Guest Editor
College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, China
Interests: organic pollutants; POPs; sediment, soil contaminants; air pollution; industrial emission; incineration emission; dioxins
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent decades, environmental pollution caused by organic pollutants—particularly persistent organic pollutants (POPs) and emerging organic contaminants (EOCs)—has drawn widespread attention and spurred rapidly growing research efforts. The study of organic pollutants remains a hotspot in the field of environmental science. Industrial production and other human activities release large quantities of organic pollutants into the environment, where they become widely distributed across various media, including air, water, sediments, and soil.

Extensive research has been conducted in multiple areas, such as the development of analytical methods, the monitoring of environmental distributions and concentrations, investigations into environmental fate, the identification of novel contaminants, and the non-target screening of organic pollutants. This Special Issue aims to collect original research papers and review articles focused on the aforementioned aspects of environmental organic pollutants.

Prof. Dr. Wenbin Liu
Guest Editor

Manuscript Submission Information

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Keywords

  • organic pollutants
  • persistent organic pollutants
  • emerging contaminants
  • new pollutants
  • air, water, soil and sediment
  • emission
  • environmental fate
  • transformation
  • target analysis and non-target analysis

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Published Papers (1 paper)

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Review

29 pages, 910 KB  
Review
Urine-to-Blood Partitioning of Per- and Polyfluoroalkyl Substances in Human Biomonitoring: Implications for Environmental Exposure Analysis and Bioaccumulation Assessment
by Peiyao Ye, Hexiang Bai, Jing Shi, Zhaomin Dong and Kai Luo
Molecules 2026, 31(11), 1880; https://doi.org/10.3390/molecules31111880 - 30 May 2026
Viewed by 376
Abstract
Per- and polyfluoroalkyl substances (PFAS) are persistent chemicals with substantial bioaccumulation potential, but their distribution between blood and urine in humans remains poorly characterized. In this review, we assessed the urine-to-blood concentration ratio (UtBCR) as a potential indicator of PFAS bioaccumulation by integrating [...] Read more.
Per- and polyfluoroalkyl substances (PFAS) are persistent chemicals with substantial bioaccumulation potential, but their distribution between blood and urine in humans remains poorly characterized. In this review, we assessed the urine-to-blood concentration ratio (UtBCR) as a potential indicator of PFAS bioaccumulation by integrating evidence from human biomonitoring studies and protein-binding data. We summarized PFAS concentrations in human serum and urine across general and highly exposed populations and identified clear compound-specific differences in blood–urine partitioning. We further examined the associations of UtBCR with carbon chain length, biological half-life, and binding-related parameters for human serum albumin (HSA), liver fatty acid-binding protein (L-FABP), and several renal transporters. Pairwise correlation analysis and partial least squares regression indicated that UtBCR was closely associated with major toxicokinetic determinants, particularly protein-binding affinity, carbon chain length, and biological half-life. Parameters related to FABP, HSA, urate transporter 1 (URAT1), and organic anion transporter 4 (OAT4) showed more consistent associations with UtBCR than those related to organic anion transporters 1(OAT1) and organic anion transporter 3 (OAT3), suggesting that plasma/tissue binding and tubular reabsorption may contribute more than active tubular secretion to PFAS blood–urine partitioning. Overall, UtBCR appears to be a useful toxicokinetic metric for comparing the relative bioaccumulation potential of PFAS. Full article
(This article belongs to the Special Issue Environmental Analysis of Organic Pollutants, 3rd Edition)
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