Advances in Small-Molecule Cancer Therapeutics: Current Challenges and Future Perspectives
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 30 April 2027 | Viewed by 346
Editors
Interests: anticancer drug discovery; cancer-related kinases; drugs acting on cell death networks; small molecules; rational drug design; medicinal chemistry; heterocyclic chemistry; computational chemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer is a group of diseases characterized by the rapid and uncontrolled proliferation of abnormal cells. Despite significant advances in diagnosis, prevention, and treatment, it remains a major global public health challenge, causing millions of deaths worldwide.
In the pursuit of more effective therapies that overcome the limitations of conventional chemotherapy, targeted therapies have emerged as a promising approach to maximize therapeutic efficacy while minimizing adverse effects. Continuous advances in understanding the multifactorial pathogenesis of cancer have enabled the identification of novel molecular targets and the subsequent development of targeted therapeutics. In this context, small molecules offer several advantages over macromolecules, including favorable pharmacokinetic properties, cost-effectiveness, and improved patient compliance.
This Special Issue will focus on current challenges, emerging trends, and future directions in small-molecule anticancer drug discovery. We cordially invite you to submit research articles and reviews related to the discovery of small molecules for cancer therapy.
We look forward to receiving your contributions.
Prof. Dr. Mehlika Dilek Altıntop
Prof. Dr. Gülşen Akalın Çiftçi
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cancer
- targeted therapy
- anticancer drug discovery
- lead identification
- small molecules
- cancer-related targets
- signaling pathways in cancer
- emerging approaches to anticancer drug design
- targeted drug delivery
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