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Special Issue "(Poly)phenols: Metabolism and Health"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: 15 June 2021.

Special Issue Editors

Dr. Letizia Bresciani
Guest Editor
The Laboratory of Phytochemicals in Physiology, Human Nutrition Unit, Department of Veterinary Science, University of Parma, 43125 Parma, Italy
Interests: nutrition; polyphenol; bioactive compounds; metabolism; bioavailability; beneficial effects; prevention; mass spectometry
Special Issues and Collections in MDPI journals
Dr. Anna Tresserra-Rimbau
Guest Editor
Department of Nutrition, Food Sciences and Gastronomy, XaRTA, School of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain
Interests: nutrition; polyphenol; bioactive compounds; epidemiology; beneficial effects; prevention; chronic diseases
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Most polyphenols cannot be absorbed as they are but need some prior structural modification. The absorption of a minimal part of the ingested polyphenols occurs in the first gastro-intestinal tract, whereas the largest part reaches the colon, where polyphenolic compounds are metabolized by the host microbiota. Polyphenol colonic catabolites are possible biologically active molecules, although their production is strictly related to gut composition, responsible for an important interindividual variability.

The understanding of polyphenol–gut microbiota interactions and the gut microbial bioconversion capability could provide more insight into the human metabolism and the bioavailability of bioactive polyphenols and represents an essential step to further investigate the potential health benefits of polyphenols and their derived metabolites. With the support of Molecules, this Special Issue welcomes manuscripts from human, animal, and in vitro studies on the metabolism of polyphenols and their implication in health and disease prevention.

Dr. Letizia Bresciani
Dr. Anna Tresserra-Rimbau
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Plant-based foods
  • Phytochemicals
  • Polyphenols
  • Bioactive compounds
  • Metabolism
  • Pharmacokinetics
  • Bioavailability
  • Colonic metabolites
  • Microbiota
  • Interindividual variability
  • Bioactivity
  • Health effects
  • Health benefits
  • Prevention
  • In vitro

Published Papers

This special issue is now open for submission.
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