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Practical Application of Aptamer-Based Biosensors in Detection of Low Molecular Weight Pollutants in Water Sources

School of Medicine, Huaqiao University, Quanzhou 362021, Fujian, China
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Author to whom correspondence should be addressed.
Molecules 2018, 23(2), 344; https://doi.org/10.3390/molecules23020344
Received: 9 January 2018 / Revised: 30 January 2018 / Accepted: 30 January 2018 / Published: 7 February 2018
(This article belongs to the Special Issue Nucleic Acid Aptamers)
Water pollution has become one of the leading causes of human health problems. Low molecular weight pollutants, even at trace concentrations in water sources, have aroused global attention due to their toxicity after long-time exposure. There is an increased demand for appropriate methods to detect these pollutants in aquatic systems. Aptamers, single-stranded DNA or RNA, have high affinity and specificity to each of their target molecule, similar to antigen-antibody interaction. Aptamers can be selected using a method called Systematic Evolution of Ligands by EXponential enrichment (SELEX). Recent years we have witnessed great progress in developing aptamer selection and aptamer-based sensors for low molecular weight pollutants in water sources, such as tap water, seawater, lake water, river water, as well as wastewater and its effluents. This review provides an overview of aptamer-based methods as a novel approach for detecting low molecular weight pollutants in water sources. View Full-Text
Keywords: aptamer; low molecular weight pollutant; water source; biosensor; environmental monitoring aptamer; low molecular weight pollutant; water source; biosensor; environmental monitoring
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MDPI and ACS Style

Zhang, W.; Liu, Q.X.; Guo, Z.H.; Lin, J.S. Practical Application of Aptamer-Based Biosensors in Detection of Low Molecular Weight Pollutants in Water Sources. Molecules 2018, 23, 344. https://doi.org/10.3390/molecules23020344

AMA Style

Zhang W, Liu QX, Guo ZH, Lin JS. Practical Application of Aptamer-Based Biosensors in Detection of Low Molecular Weight Pollutants in Water Sources. Molecules. 2018; 23(2):344. https://doi.org/10.3390/molecules23020344

Chicago/Turabian Style

Zhang, Wei; Liu, Qing X.; Guo, Zhi H.; Lin, Jun S. 2018. "Practical Application of Aptamer-Based Biosensors in Detection of Low Molecular Weight Pollutants in Water Sources" Molecules 23, no. 2: 344. https://doi.org/10.3390/molecules23020344

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