Special Issue "Natural Bioactive Compounds in the Prevention and Treatment of Chronic Diseases"
Deadline for manuscript submissions: closed (30 November 2020).
Interests: allergic contact dermatitis; nutritional immunology; mucosal immunology; interleukins; polyphenols; psoriasis; toll-like receptors
Interests: N-3 fatty acids (marine or vegetal origin) and hepatoprotective effects in steatosis and inflammatory models; beneficial impacts of natural antioxidants from fruits and vegetable in metabolic disturbance, especially in adipose tissue and liver
The prevalence of chronic diseases, such as obesity, diabetes, cardiovascular diseases, neurodegeneration, cancer, non-alcoholic fatty liver disease, and allergic-autoimmune diseases, among others, is currently increasing worldwide. These diseases have in common a complex interaction between genetic, metabolic and environmental factors. In this context, recent basic and clinical investigations have demonstrated the importance of different natural bioactive compounds present in food or herbs as fundamental elements in the prevention and/or treatment of chronic diseases. Particularly, the role of natural bioactive compounds in cell and tissue protection against injury (i.e., oxidative stress, inflammation, endoplasmic reticulum stress) has been explored. The principal natural bioactive compounds are: i. natural antioxidants (tocopherols, polyphenols, carotenoids, etc.), ii. vegetal sterols (such as phytosterols), iii. short and long chain polyunsaturated fatty acids, iv. bioactive peptides, and v. pre- and probiotics. These molecules may regulate many cellular processes in different tissues under pathological situations. In this sense, the natural bioactive compounds in food and herbs play a relevant and direct role in regulating several of the metabolic and molecular pathways involved in the prevention and treatment of chronic diseases.
This Special Issue of Molecules is devoted to recent advances about the natural bioactive compounds in the prevention and treatment of chronic diseases. For this reason, it is necessary to identify and understand molecular pathways involved in these events in order to develop nutritional or pharmaceutical strategies that contribute to the prevention and treatment of chronic diseases.
Prof. Dr. Thea Magrone
Dr. Rodrigo Valenzuela
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Chronic diseases
- Natural bioactive compounds in food or herbs
- Natural antioxidants and vegetal sterols
- Short and long chain polyunsaturated fatty acids
- Bioactive peptides and, pre- and probiotics