Special Issue "Metal Anticancer Complexes"
Deadline for manuscript submissions: 15 November 2019
Dr. Kogularamanan Suntharalingam
King's College London, Department of Chemistry, London, United Kingdom
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Interests: metallopharmaceuticals; metallodrugs; biorganometallic complexes; biologically-active metal clusters; metal-based drug delivery agents; cancer metallomics; metal–protein interactions; metal–nucleic acid interactions; theranostics metal complexes; cancer imaging agents
The identification of chemical agents with therapeutic potential is of high importance for research in bioinorganic chemistry and medicinal chemistry. Traditionally, organic molecules have dominated research in this area, and thus relatively little is known about the therapeutic properties of inorganic compounds. Despite breakthrough therapies for the treatment of cancer based on platinum, arsenic, and ruthenium compounds, metal complexes have received relatively little attention from the pharmaceutical industry and the chemical biology/medicinal chemistry research community as a whole. A number of small spinout companies have now started in-house research programs aimed at addressing key bioinorganic aspects of medicine; however, few large pharmaceutical companies have such mechanisms in place. The versatility of metal complexes, which arises from the choice of metal, oxidation state, redox activity, number and type of ligands, coordination geometry, and magnetic and optical properties, deserves to be investigated further in the context of rational drug design. This Special Issue of Molecules aims to showcase recent advancements in any aspect of metal-based anticancer therapeutics design and development. Synthetic, biophysical, in vitro, and in vivo studies are all welcome. Review articles that describe the current state of metal-based cancer therapeutics development, in any context, are also welcome.
Dr. Kogularamanan Suntharalingam
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- biorganometallic complexes
- biologically-active metal clusters
- metal-based drug delivery agents
- cancer metallomics
- metal–protein interactions
- metal–nucleic acid interactions
- theranostics metal complexes
- cancer imaging agents