Special Issue "Coumarins, Xanthones and Related Compounds"
Deadline for manuscript submissions: closed (15 September 2015)
It has long been known that coumarins (α-pyrones) and xanthones (γ-pyrones) form a large class of naturally occurring compounds exhibiting a wide range of biological activities. However, the interest of the scientific community for these secondary metabolites, as well as for structural analogues, has never decreased since these "old compounds" are constantly generating promising - and sometimes unexpected - therapeutic perspectives. For instance, the xanthone Vadimezan (ASA404 or (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)-acetic acid) was recently developed as a tumor vascular-disrupting agent, whereas many coumarin derivatives are under investigation for their anti-oxidant and anti-inflammatory properties. However, by far, these studies are not restricted to biological activities since coumarins, as an example, may also constitute a molecular model of choice to study hydrogen bonding in the electronic excited state, or even the photovoltaic performances of specific dyes. Therefore, it is probably the right time to launch this third edition, which hopefully will address many fascinating aspects of "coumarins, xanthones and related compounds".
Prof. Dr. Pascal Richomme
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