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Molecules 2016, 21(3), 294;

Xanthones of Lichen Source: A 2016 Update

Laboratoire de Pharmacognosie, Equipe PNSCM, (ISCR UMR CNRS 6226), Faculté des Sciences Pharmaceutiques et Biologiques, 2 Avenue du Professeur Léon Bernard, 35043, Rennes Cédex, France
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 25 January 2016 / Revised: 21 February 2016 / Accepted: 23 February 2016 / Published: 2 March 2016
(This article belongs to the Special Issue Coumarins, Xanthones and Related Compounds)
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An update of xanthones encountered in lichens is proposed as more than 20 new xanthones have been described since the publication of the compendium of lichen metabolites by Huneck and Yoshimura in 1996. The last decades witnessed major advances regarding the elucidation of biosynthetic schemes leading to these fascinating compounds, accounting for the unique substitution patterns of a very vast majority of lichen xanthones. Besides a comprehensive analysis of the structures of xanthones described in lichens, their bioactivities and the emerging analytical strategies used to pinpoint them within lichens are presented here together with physico-chemical properties (including NMR data) as reported since 1996. View Full-Text
Keywords: biosynthesis; polyketides; fungi; NMR spectroscopy; bioactivity; lichexanthone; islandicin; thiomelin; secalonic acids biosynthesis; polyketides; fungi; NMR spectroscopy; bioactivity; lichexanthone; islandicin; thiomelin; secalonic acids

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Le Pogam, P.; Boustie, J. Xanthones of Lichen Source: A 2016 Update. Molecules 2016, 21, 294.

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