Special Issue "Chitin and Chitosan Derivatives: Biological Activities and Application 2020"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (31 December 2020).
Interests: chitosan and chitosan conjugates; synthesis; structure activity relationship (SAR); spectroscopy; antimicrobial chitosan conjugates and natural compound derivatives; photochemistry; NMR analysis; nanomedicine; nanoparticles; regenerative medicine; antimicrobial activity; absorption enhancers; photodynamic therapy; cancer therapy; mathematical modeling and design of experiment (DOE)
Special Issues and Collections in MDPI journals
2. Biomedical Engineering Department, Reykjavik University, 101 Reykjavík, Iceland
Interests: platelet lysates in biomaterial use; bone tissue engineering; bioreactors for bone tissue engineering
Interests: biocontrol; nematophagous fungi; entomopathogenic fungi; chitosan; plant pathology; endophytes; fungal "omics"
Special Issues and Collections in MDPI journals
Special Issue in Journal of Fungi: Fungal-Insect Interactions
Special Issue in International Journal of Molecular Sciences: Host-Microbe Interaction 2019
Special Issue in International Journal of Molecular Sciences: Host-Microbe Interaction 3.0
Topical Collection in Encyclopedia: Encyclopedia of Fungi
Chitosan is a unique biopolymer that is derived from chitin. It can be polycationic under somewhat acidic conditions, and this separates it from other common polysaccharides that are either neutral or have a negative net charge in aqueous solutions. It is also biocompatible and has significant biological activity, most notably an antimicrobial effect, and has also been shown to stimulate tissue regeneration. Chitosan and chitooligosaccharides have been marked as neutraceuticals and used in wound treatment and in scaffolds for bone tissue engineering. There is also much interest in applications in drug delivery, including the use of chitosan as an absorption enhancer, in nanoparticles and non-viral gene delivery. Chemical modification of the chitin and chitosan backbone can be used to further expand the applicability and bioactivity of these biopolymers. Polar moieties can be introduced to improve solubility and biological activity under certain conditions, and conjugates with novel activities can created by covalent linking to other biomolecules. The derivatization of chitin and chitosan is now a very active research field, where new derivatives have been created using different approaches, including conventional synthesized chemical procedures, sometimes also involving the use of protection groups via ‘‘click chemistry“ or enzymatic grafting or by crosslinking to make biocompatible polymer networks.
The aim this Special Issue is to highlight these developments and bring toghether new findings related to biologically active chitin and chitosan derivatives. Reporting of new approaches for chemical modification and charactierization, including detailed structural characterization by NMR or other methods as well as exciting new findings with regard to biological activity and the application of chitin and chitosan derivatives, will be included in this Special Issue.
Dr. Már Másson
Prof. Ólafur Sigurjónsson
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- protection groups
- click chemistry
- molecular weight
- cell growth
- wound healing
- bone growth