Anticancer Properties of Natural and Derivative Products

Dear Colleagues,

This Special Issue aims to collect and disseminate some of the most significant and recent contributions in the use of natural and derivative compounds to cancer prevention and treatment. Natural products are bioactive compounds synthesized by terrestrial and marine plants, microorganisms, and animals. Traditionally, they have been used in the prevention and treatment of various human diseases in different cultures. In parallel, chemical derivatives of these natural compounds have been used in order to enhance their bioactivities. During the last ten years, most of them have been reported to have a variety of interesting and significant biological properties, such as analgesic, anti-allodynic, antidiabetic, antioxidant, antiparasitic, antimicrobial, antiviral, anti-atherogenic, anti-inflammatory, antiproliferative, antitumor, and growth-stimulating activities as well as cardio- and neuroprotective activity. Special attention has been focused on the study of their antitumor capacity through the potential modulation of cancer initiation and growth, cellular differentiation, apoptosis and autophagy, angiogenesis, and metastatic dissemination. Moreover, a considerable number of studies have related their anticancer effects with their anti-inflammatory and antioxidant activities. Reports on the biological activity of natural extracts will only be considered if they are accompanied with proper chemical characterization.

Prof. Dr. José Antonio Lupiáñez
Dr. Amalia Pérez-Jiménez
Dr. Eva E. Rufino-Palomares
Guest Editors

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