Special Issue "Feature Papers of Micromachines in Biology and Biomedicine 2020"

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".

Deadline for manuscript submissions: 31 December 2020.

Special Issue Editor

Prof. Dr. Nam-Trung Nguyen
Website SciProfiles
Guest Editor
Queensland Micro- and Nanotechnology Centre, Griffith University, West Creek Road, Nathan, Queensland 4111, Australia
Interests: microfluidics; nanofluidics; micro/nanomachining technologies; micro/nanoscale science; instrumentation for biomedical applications
Special Issues and Collections in MDPI journals

Special Issue Information

We are pleased to announce the Special Issue entitled " Feature Papers of Micromachines in Biology and Biomedical Sciences 2020". In the past several years, we cooperated with excellent scholars and research groups to publish several high-impact high-quality works, which have already been cited according to Web of Science. We aim to introduce a new insight into science development or cutting-edge technology related to micromachines in the fields of biology and biomedical sciences, which will make a great contribution to the community.

This Special Issue will be a collection of high-quality papers from excellent scholars around the world. Both original research articles and comprehensive review papers are welcome. The papers will be published, free of charge, with full open access after peer review to benefit both authors and readers.

You are welcome to send short proposals for submissions of Feature Papers to our Editorial Office ([email protected]) before the submission. The proposals will first be evaluated by the Editors. Please note that selected full papers will still be subjected to a thorough and rigorous peer review.

We look forward to receiving your excellent work.

Prof. Nam-Trung Nguyen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • BioMEMS
  • miniaturized biosensors
  • microarrays
  • DNA chips
  • PCR chips
  • electronic noses
  • organ-on-a-chip
  • microfluidic cell culture
  • point-of-care diagnostic chips
  • μ-TAS
  • molecular imprinting
  • applications in medicine, biomedical research, drug discovery, environment, food, health, security, and safety.

Published Papers (1 paper)

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Open AccessArticle
Transesterification in Microreactors—Overstepping Obstacles and Shifting Towards Biodiesel Production on a Microscale
Micromachines 2020, 11(5), 457; https://doi.org/10.3390/mi11050457 - 28 Apr 2020
Biodiesel, which was earlier used only as an alternative fuel, is now an indispensable component of commercial diesel. Conventional production processes are unable to cope with the increasing demand for biodiesel, and therefore more and more work is being done to intensify the [...] Read more.
Biodiesel, which was earlier used only as an alternative fuel, is now an indispensable component of commercial diesel. Conventional production processes are unable to cope with the increasing demand for biodiesel, and therefore more and more work is being done to intensify the existing processes. The intensification of the biodiesel production process, taking into account the environmental and economic factors, is based on increasing productivity. One way to achieve that is by reducing the volume of production units. The application of the enzymatic reaction path, while reducing the volume of process equipment to the micro-level, has significantly magnified the productivity of the biodiesel production process, which is primarily due to better mass transfer in microsystems. Additional breakthrough is the use of deep eutectic solvents (DES) instead of buffers for enzyme stabilization. In this study, a lipase from Thermomyces lanuginosus (TlL) (both commercial and produced by solid-state fermentation) was used as a catalyst for biodiesel production. Edible and waste sunflower oil, as well as methanol, were used as substrates. The reaction mediums were buffer and DES. The transesterification reaction was carried out in a batch reactor and the emphasis was made on different microreactor configurations. The highest yield of 32% for residence time of only τ = 30 min was obtained in the microreactor system with an emulsion of waste oil and a commercial enzyme suspended in a buffer. This indicates that enzymatic transesterification could be a valuable reaction path for dealing with waste oils. Furthermore, biodiesel synthesis in DES showed somewhat lower yields, but by increasing the water content in the system, the reaction could prove much better results. In the end, the effects of reaction conditions on the volumetric productivity of the process were analyzed. Full article
(This article belongs to the Special Issue Feature Papers of Micromachines in Biology and Biomedicine 2020)
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