Special Issue "Marine Metabolomics"
A special issue of Metabolites (ISSN 2218-1989).
Deadline for manuscript submissions: closed (30 April 2017)
Dr. RuAngelie Edrada-Ebel
Metabolomics was instigated by the concepts of metabolic profiling. Metabolic profiling found its application in plant science between the late 80s and early 90s by utilising hyphenated chromatography with UV spectroscopy, mass spectrometry, and later with NMR spectroscopy targeting relevant metabolites for agricultural projects and improve food production. In the late 90s and the following decades thereafter, metabolic profiling transpired to play a central role in plant functional genomics which then evolved to be a new “omics” platform technology now known as metabolomics. With the developments in computing and data processing, it was then possible to conduct an untargeted analysis of all the metabolites. To date, metabolomics is rapidly turning out to be the leading "omics" platform for systems biology as evidenced by almost equal ratio of the number of papers published in metabolomics alone to those published under the field of genomics, metagenomics, proteomics, transcriptomics, and lipidomics all together. The "omics" platform has found its application in different fields of study, from biomedical analysis to plant science but only very recently in marine research with an abrupt increase in the number of publications in this field only occurring in the last three years. However, taking into consideration the number of marine metabolomics papers in comparison to the number of papers published for the "omics" platform, the ratio is quite low at approximately only 15% of entire "omics" publication in the field of marine metabolomics.
Metabolic profiling in marine research started with the introduction of photo-diode arrays along with HRFTMS detectors combined with high-performance liquid chromatography which enhanced dereplication work. By the beginning of the millennium, high-throughput sequencing was emerging and there was a shift from pure genetic research to procurement of gene function and expression. This issue will cover applications in marine ecology, biotechnology, and bioprospecting.
Dr. RuAngelie Edrada-Ebel
Manuscript Submission Information
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- metabolomics profiling