The Impact of Diet on the Metabolism and Body Composition of Patients with Skin Diseases

Dear Colleagues,

Skin diseases such as psoriasis, atopic dermatitis, acne, and hidradenitis suppurativa are increasingly recognized as systemic inflammatory conditions closely connected to metabolic dysfunction and alterations in body composition. Growing evidence shows that dietary patterns influence lipid and glucose metabolism, oxidative stress, inflammation, and gut–skin axis dynamics, ultimately modulating disease severity and therapeutic outcomes. Additionally, excess adiposity along with diet-induced metabolic perturbations appears to amplify inflammatory phenotypes and impair clinical response.

This Special Issue aims to collect high-quality contributions elucidating mechanistic links and clinical implications of nutrition in dermatological conditions. Submissions are invited on the following topics: (1) metabolic pathways through which diet affects cutaneous inflammation; (2) the impact of structured dietary interventions (such as anti-inflammatory dietary patterns, caloric restriction, ketogenic therapies, and targeted nutraceuticals) on metabolic biomarkers and body composition; (3) metabolomics, lipidomics, and imaging techniques to characterize diet-induced metabolic shifts; (4) characteristic body composition phenotypes in patients with skin diseases; and (5) the role of adipose tissue distribution, metabolic flexibility, and endocrine–immune interactions in shaping disease trajectories.

By integrating metabolic, nutritional, and dermatological perspectives, this Special Issue seeks to advance evidence-based strategies capable of improving both systemic metabolism and skin-related clinical outcomes.

Dr. Giuseppe Annunziata
Prof. Dr. Luigi Barrea
Prof. Dr. Matteo Megna
Guest Editors

Manuscript Submission Information

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