Metabolomics in Neurodegenerative Diseases, 2nd Edition
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Cell Metabolism".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 101
Special Issue Editors
Interests: Alzheimer’s disease; mild cognitive impairment; Parkinson’s disease; delirium; neurodegeneration; metabolomics; biomarkers; biochemistry; etiology; pathophysiology
Special Issues, Collections and Topics in MDPI journals
Interests: delirium; Alzheimer’s disease; Parkinson’s disease; metabolomics; biomarkers; biochemistry; etiology; pathophysiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The application of metabolomics in neurodegenerative diseases could provide molecular insights into conditions such as Alzheimer's disease and Parkinson's disease. This promising discipline scrutinizes the intricate metabolic profiles of biological systems, aiding in the identification of biomarkers, unraveling disease mechanisms, and enhancing diagnostic precision. By employing advanced analytical techniques, such as mass spectrometry and nuclear magnetic resonance spectroscopy, researchers can evaluate the alterations in metabolite patterns associated with neurodegeneration. These alterations encompass a disrupted energy metabolism, aberrant lipid processing, and amino acid imbalances, offering valuable information regarding the intricate pathophysiology of these diseases. Metabolomics also offers opportunities for the development of novel therapeutic targets and personalized interventions. However, challenges related to standardization, data integration, and understanding the causative relationships remain. This Special Issue of Metabolites underscores the role of metabolomics in enhancing our comprehension of neurodegenerative disorders, fostering innovative diagnostic avenues and treatment strategies.
Dr. Stewart Francis Graham
Dr. Nazia M. Saiyed
Guest Editors
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Keywords
- neurodegenerative disease
- Alzheimer’s
- Parkinson’s
- Huntington’s
- ALS
- neurodegeneration
- bi-omarkers
- metabolism
- etiology
- pathophysiology
- biochemistry
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