New Insights into Breast Cancer: Current Controversies and Future Perspectives

Dear Colleagues,

Breast cancer is the most frequently diagnosed cancer and the commonest cause of cancer death among women, despite diagnostic and therapeutic advances in the last few decades.

Thanks to advances in breast imaging, prevention campaigns, and public awareness, breast cancer is mostly diagnosed at an early stage. This translates into the possibility of applying “breast conserving therapies”, resulting in very high 5-year overall survival rates.

Nevertheless, approximately 8.5% of American and 4% of European patients still present with locally advanced breast cancer, whereas 6–7% have distant metastasis at diagnosis.

In such a variable scenario, the multidisciplinary calibration of therapeutic protocols, based on recent advances in breast imaging, breast conserving and reconstructive surgical techniques, multipanel gene essays, and systemic treatments (e.g., hormone therapy, poly-chemotherapy, and molecular-targeted therapy), can lead to more efficient local and systemic control of the disease.

The aim of this Special Issue is to provide a wide range of the most recent diagnostic and therapeutic protocols in breast cancer to provide the reader with updated information regarding every aspect of recent advances and future challenges.

Dr. Alejandro Martin Sanchez
Dr. Angela Bucaro
Dr. Flavia de Lauretis
Guest Editors

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• breast cancer treatment
• oncoplastic surgery
• conservative mastectomy
• breast reconstruction
• sentinel node biopsy
• chemotherapy
• radiotherapy
• integrated therapies