Photodynamic Therapy for Medical Applications: From Infections to Tissue Regeneration
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: 25 November 2025 | Viewed by 60
Special Issue Editors
Interests: oral mucosa diseases; periodontal diseases and therapy; oral potentially malignant disorders (OPMDs); PDT in dentistry; oral surgery; chronic mucosal diseases; otorhinolaryngology; inflammatory diseases of the oral cavity; tissue regeneration and wound healing; laser and light-based therapies in oral medicine
Special Issues, Collections and Topics in MDPI journals
Interests: targeted immunotherapy; targeted photodynamic therapy; vascular tissue; necrosis; neoplasms; macular degeneration; choroidal neovascularization; lung neoplasms; breast neoplasms; neoplasm metastasis; melanoma; tumor immunology; immunotherapy, particularly antibody and CAR-NK cell immunotherapy; photodynamic therapy; gene therapy; cancer pathology; tumor angiogenesis; tumor microenvironment; immune cells; NK cells; MDSC; cancer stem cells
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Photodynamic therapy (PDT) is an innovative and rapidly evolving treatment modality that harnesses the interaction of light, photosensitizers, and molecular oxygen to induce selective therapeutic effects. Originally developed for cancer treatment, PDT has expanded into numerous medical applications, including antimicrobial therapy, inflammation control, and tissue regeneration. This minimally invasive approach offers a promising alternative to traditional therapies by providing targeted action with reduced side effects and antimicrobial resistance concerns.
This Special Issue aims to provide a comprehensive exploration of PDT’s role in modern medicine and healthcare, spanning its fundamental mechanisms to clinical applications. We welcome original research, reviews, and clinical studies on novel photosensitizers, optimized light delivery systems, innovative treatment protocols, and combination therapies. Topics of interest include PDT in the management of microbial infections (antimicrobial PDT), oral potentially malignant disorders (OPMDs), oncology, dermatology, chronic wounds, and regenerative medicine. Additionally, research addressing mechanistic insights, safety considerations, and strategies to enhance PDT efficacy and selectivity is highly encouraged.
As PDT continues to gain traction in medical practice, this Special Issue will serve as a valuable resource for researchers, clinicians, and industry professionals working to advance its applications. We invite submissions that contribute to the growing body of evidence supporting PDT as a versatile, effective, and sustainable therapeutic approach across multiple medical disciplines.
Dr. Rafał Wiench
Dr. Zhiwei Hu
Guest Editors
Jakub Fiegler-Rudol
Assistant Guest Editor
Manuscript Submission Information
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Keywords
- photodynamic therapy (PDT)
- photosensitizers
- reactive oxygen species (ROS)
- infections and antimicrobial PDT (aPDT)
- tissue regeneration and wound healing
- oral potentially malignant disorders (OPMDs)
- oncology and cancer treatment
- dermatology and skin disorders
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