Special Issue "Characterization and Clinical Management of Dilated Cardiomyopathy"
Deadline for manuscript submissions: 31 December 2019
Prof. Marco Merlo
Cardiovascular Department, Azienda Sanitaria Universitaria Integrata of Trieste ‘ASUITS’, Trieste, Italy
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Interests: heart failure; dilated cardiomyopathy; myocarditis; genetics; non-ischemic cardiomyopathy; cardiac magnetic resonance; long term survival; arrhythmic risk stratification; left ventricular reverse remodeling
Dilated cardiomyopathy (DCM) is a particular phenotype of non-ischemic systolic heart failure, frequently recognizing a genetic background and affecting relatively young patients with few comorbidities. Nowadays, long-term survival of DCM patients has been markedly improved due to an early diagnosis, and the uninterrupted and tailored follow-up under constant optimal medical and non-pharmacological evidence-based treatments. Nevertheless, DCM is still one of the most common causes of heart transplantation in the Western World. Clinical management requires an integrated and systematic use of diagnostic tools and a deeper investigation of the basic mechanisms underlying the disease. However, several emerging issues remain still debated. Specifically, the genotype-phenotype correlation, the role of advanced imaging techniques and genetic testing, the lack of appropriate risk stratification models, the need of multiparametric and multidisciplinary approach for device implantation, and a continuous reclassification of the disease during follow-up remain challenging issues in clinical practice.
Therefore, the aim of this special issue is to shed the light on the most recent advancements in characterization and clinical management of DCM, in order to unveil the conundrum of this particular disease.
Prof. Marco Merlo
Manuscript Submission Information
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- dilated cardiomyopathy
- non-ischemic cardiomyopathy
- heart failure with reduced ejection fraction
- cardiac magnetic resonance
- long term survival
- arrhythmic risk stratification