Sjogren’s Syndrome: Pathogenesis, Clinical Spectrum, Diagnosis and Therapies
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Immunology".
Deadline for manuscript submissions: closed (10 June 2022) | Viewed by 38418
Special Issue Editor
Special Issue Information
Dear Colleagues,
Sjogren’s syndrome is a chronic autoimmune disease characterized by chronically inflamed exocrine tissues resulting mainly in oral and ocular dryness. However, beyond local dryness issues, systemic manifestations affecting virtually any organ system, including, among others, chronic fatigue, Raynaud’s phenomenon, musculoskeletal complaints, renal, liver and neurological related issues, often occur. Malignant disease in the form of lymphoproliferation is a well-established disease complication, and comorbidities such as accelerated atherosclerosis and mental health issues are also increasingly recognized. Given the wide spectrum of clinical manifestations, disease diagnosis can often be challenging. Despite the progress in understanding underlying pathogenetic mechanisms, effective therapeutic strategies are limited so far for both local and systemic disease manifestations.
In view of these challenges, we invite researchers to contribute original research articles, reviews, and case series aiming at pathogenesis, clinical spectrum, diagnosis, and therapeutic interventions in Sjogren’s syndrome.
Dr. Clio P. Mavragani
Guest Editor
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Keywords
- Sjogren’s syndrome
- Pathogenesis
- Diagnosis
- Clinical manifestations
- Therapy