Infections, Complications and Management of Kidney Transplantation
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nephrology & Urology".
Deadline for manuscript submissions: closed (5 April 2022) | Viewed by 38934
Special Issue Editors
Interests: kidney transplantation; bacterial and viral infection; posttransplant diabetes; rejection; cancer; cardiovascular complications; immunosuppression
Interests: kidney transplantation; bacterial and viral infection; posttransplant diabetes; rejection; cancer; cardiovascular complications; immunosuppression
Special Issue Information
Dear Colleagues,
Renal transplantation is the best treatment for end-stage renal disease patients and it is widely delivered in developed countries. However, there are a large number of complications that arise after transplantation hampering its short- and long-term outcomes. The quality of the transplanted graft (living, standard criteria and expanded criteria donors including donors after circulatory death), the recipient characteristics (age and comorbidities) and the immunological risk (HLA or ABO barriers) aids clinicians to define the proper immunosuppressive regimen for each patient. However, despite the wide experience of clinicians managing renal transplants, patient and graft survival have not substantially improved during recent years. Short-term complications include bacterial and viral infections, posttransplant diabetes mellitus and clinical/subclinical rejection. Long-term complications include patient’s death mainly related with cardiovascular events and cancer and graft loss due to chronic rejection or recurrence of the primary disease. Despite the big effort to include new biomarkers to improve renal transplant outcomes, only monitoring of HLA donor-specific antibodies and nuclear acid testing for some viruses (cytomegalovirus and polyoma BK virus) have been incorporated into the clinical routine.
In the present Special Issue of the Journal of Clinical Medicine, we aim to collect a number of reviews and original articles that highlight significant advances in the management of renal transplants and its complications. As complications directly impact on the health and the outcome of transplant recipients, this Special Issue should increase the awareness as well as the knowledge of transplant physicians and researchers in these issues.
Potential topics include but are not limited to the following:
- Donor quality and graft outcome;
- Antibody-mediated and cellular clinical and subclinical rejection;
- Monitoring and management of cytomegalovirus infection;
- Monitoring and management polyoma BK virus;
- Bacterial infections after transplantation;
- Posttransplant diabetes mellitus;
- Skin and non-skin cancer in renal transplants;
- Cardiovascular risk and complications in transplant candidates and transplant recipients;
- New biomarkers to monitor renal transplants;
- Tailored immunosuppression;
- Monitoring of immunosuppression.
Prof. Francesc Moreso
Prof. Daniel Serón
Guest Editors
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Keywords
- kidney transplantation
- bacterial and viral infection
- posttransplant diabetes
- rejection
- cancer
- cardiovascular complications
- immunosuppression
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