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18 November 2025
Journal of Clinical Medicine | Highly Cited Papers and Hot Topic Special Issues on Endocrine Diseases


The endocrine system acts as the body's “command center”, and its dysfunction can lead to a variety of endocrine diseases, which have become a global health challenge. We would like to invite you to read our collection of highly cited papers on endocrine diseases published in Journal of Clinical Medicine (JCM, ISSN: 2077-0383). We hope they provide useful insights for researchers in selecting treatment options and developing health management strategies. Moreover, several hot topic Special Issues pertaining to this topic are currently open for submissions.

1. “The Lipid Accumulation Product Index (LAP) and the Cardiometabolic Index (CMI) Are Useful for Predicting the Presence and Severity of Metabolic Syndrome in Adult Patients with Obesity”
by Sofia Tamini, Adele Bondesan, Diana Caroli and Alessandro Sartorio
J. Clin. Med. 2024, 13(10), 2843; https://doi.org/10.3390/jcm13102843
Full text available online: https://www.mdpi.com/2077-0383/13/10/2843

2. “Pituitary Apoplexy: An Updated Review”
by Pedro Iglesias
J. Clin. Med. 2024, 13(9), 2508; https://doi.org/10.3390/jcm13092508
Full text available online: https://www.mdpi.com/2077-0383/13/9/2508

3. “Complete Blood Count (CBC)-Derived Inflammation Indexes Are Useful in Predicting Metabolic Syndrome in Adults with Severe Obesity”
by Alice Marra, Adele Bondesan, Diana Caroli and Alessandro Sartorio
J. Clin. Med. 2024, 13(5), 1353; https://doi.org/10.3390/jcm13051353
Full text available online: https://www.mdpi.com/2077-0383/13/5/1353

4. “Interactions between the Exocrine and the Endocrine Pancreas”
by Roberto Valente, Alessandro Coppola, Chiara Maria Scandavini, Asif Halimi, Annelie Magnusson, Augusto Lauro, Ira Sotirova, Urban Arnelo and Oskar Franklin
J. Clin. Med. 2024, 13(4), 1179; https://doi.org/10.3390/jcm13041179
Full text available online: https://www.mdpi.com/2077-0383/13/4/1179

5. “Barriers to Type 1 Diabetes Adherence in Adolescents”
by Sarah Azar, Noa Maroun Abou Jaoude, Andrzej Kędzia and Elżbieta Niechciał
J. Clin. Med. 2024, 13(19), 5669; https://doi.org/10.3390/jcm13195669
Full text available online: https://www.mdpi.com/2077-0383/13/19/5669

6. “Pancreatitis Risk Associated with GLP-1 Receptor Agonists, Considered as a Single Class, in a Comorbidity-Free Subgroup of Type 2 Diabetes Patients in the United States: A Propensity Score-Matched Analysis”
by Mark Ayoub, Harleen Chela, Nisar Amin, Roberta Hunter, Javaria Anwar, Veysel Tahan and Ebubekir Daglilar
J. Clin. Med. 2025, 14(3), 944; https://doi.org/10.3390/jcm14030944
Full text available online: https://www.mdpi.com/2077-0383/14/3/944

7. “Challenges of Managing Type 3c Diabetes in the Context of Pancreatic Resection, Cancer and Trauma”
by Colton D. Wayne, Chahrazed Benbetka, Gail E. Besner and Siddharth Narayanan
J. Clin. Med. 2024, 13(10), 2993; https://doi.org/10.3390/jcm13102993
Full text available online: https://www.mdpi.com/2077-0383/13/10/2993

8. “Impact of Concurrent Exercise Training on Cardiac Autonomic Modulation, Metabolic Profile, Body Composition, Cardiorespiratory Fitness, and Quality of Life in Type 2 Diabetes with Cardiac Autonomic Neuropathy: A Randomized Controlled Trial”
by Saima Zaki, Md Farhan Alam, Saurabh Sharma, Said El-Ashker, Mohammad Ahsan and Shibili Nuhmani.
J. Clin. Med. 2024, 13(13), 3910; https://doi.org/10.3390/jcm13133910
Full text available online: https://www.mdpi.com/2077-0383/13/13/3910

9. “Early-Onset Colorectal Cancer: Are Neuroendocrine Tumors or Adenocarcinomas the Culprit? Analysis of the Largest U.S. Cancer Incidence Database, 2001–2020”
by Yazan Abboud, Madison Fraser, Imran Qureshi and Kaveh Hajifathalian
J. Clin. Med. 2024, 13(4), 1098; https://doi.org/10.3390/jcm13041098
Full text available online: https://www.mdpi.com/2077-0383/13/4/1098

10. “Adrenal Cysts: To Operate or Not to Operate?”
by Ivana Bozic Antic, Igor Djurisic and Srdjan Nikolic
J. Clin. Med. 2024, 13(3), 846; https://doi.org/10.3390/jcm13030846
Full text available online: https://www.mdpi.com/2077-0383/13/3/846

Special Issues:

Chronic Complications of Type 2 Diabetes: Prevalence, Prevention, and Management
Guest Editor: Dr. Ilias Migdalis
Submission deadline: 20 January 2026

Neuroendocrine Tumors: Challenges and Future Perspectives (Second Edition)
Guest Editors: Dr. Anna La Salvia
Dr. Giuseppe Lamberti
Submission deadline: 20 February 2026

New Advances and Clinical Outcomes of Pediatric Endocrinology
Guest Editor: Dr. Gerdi Tuli
Submission deadline: 28 February 2026

Recent Advances in Endocrine Surgery—2nd Edition
Guest Editor: Dr. Gregorio Scerrino
Submission deadline: 20 April 2026

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