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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Skin, Autoimmunity and Inflammation 2.0

edited by

Annamaria Offidani

and

Federico Diotallevi

submission deadline 20 Sep 2025 | 2 articles | Viewed by 22320 | Submission Open

Keywords: skin diseases; skin immunology; skin autoimmunity; skin inflammation; inflammatory cytokines; biological therapies; immunotherapy; target therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

From Molecular Insights to Novel Therapies: Neurological Diseases

edited by

Margarita Neganova

submission deadline 20 Sep 2025 | 13 articles | Viewed by 22295 | Submission Open

Keywords: neurological diseases; neurodegenerative diseases; epilepsy; mental illness; transgenic animal models; molecular pathways; metabolism disabilities; mitochondrial dysfunction; oxidative stress; disturbances in epigenetic regulation

(This special issue belongs to the Section Molecular Neurobiology)

Novel Biosystems in Toxicology and Pharmacology

edited by

Ricardo Lagoa

Manuel Aureliano

and

Paula A. Videira

submission deadline 20 Sep 2025 | 4 articles | Viewed by 21581 | Submission Open

(This special issue belongs to the Section Molecular Biology)

Oxygen Variations, 2nd Edition

edited by

Costantino Balestra

Simona Mrakic-Sposta

and

Gerardo Bosco

submission deadline 20 Sep 2025 | 6 articles | Viewed by 19787 | Submission Open

Keywords: hypoxia; hyperoxia; normoxia; biochemichal response; integrative approach; normo-hypo-hyperbaric; molecular research; gene expression; adaptive reactions; extreme environments

(This special issue belongs to the Section Molecular Biology)

Recent Approaches for Wound Treatment—2nd Edition

edited by

César Viseras

Luana Perioli

and

Cinzia Pagano

submission deadline 20 Sep 2025 | 7 articles | Viewed by 19694 | Submission Open

(This special issue belongs to the Section Molecular Pharmacology)

Reproductive Endocrinology Research

edited by

Tsung-Hsien Lee

submission deadline 20 Sep 2025 | 5 articles | Viewed by 19356 | Submission Open

Keywords: molecular endocrinology; reproductive genetics; hormonal signaling pathways; fertility and infertility; epigenetics in reproduction; environmental impact on reproduction

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Biomaterials for Dental and Orthopedic Applications

edited by

Lia Rimondini

and

Elena Varoni

submission deadline 20 Sep 2025 | 8 articles | Viewed by 14801 | Submission Open

(This special issue belongs to the Section Materials Science)

Demyelinating Diseases: From Molecular Mechanisms to, Therapeutic Strategies—3rd Edition

edited by

Antonietta Bernardo

submission deadline 20 Sep 2025 | 4 articles | Viewed by 14610 | Submission Open

Keywords: biomarkers; cellular and molecular biology; cell differentiation; cellular metabolism; demyelinating diseases; drug developing strategies and drug repositioning; glia cell (oligodendrocytes; astrocytes and microglia); inflammation; lipid metabolism; mitochondria; myelination and remyelination nuclear receptors; nutraceuticals; signal transduction mechanisms; target identification

(This special issue belongs to the Section Molecular Neurobiology)

Novel Natural Compound for Wound and Tissue Repair and Regeneration: 3rd Edition

edited by

Elia Ranzato

and

Simona Martinotti

submission deadline 20 Sep 2025 | 6 articles | Viewed by 14468 | Submission Open

Keywords: wound repair; tissue regeneration; natural compounds; phytochemicals; molecular mechanisms

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Recent Research in Gut Microbiota–Gut–Brain Axis

edited by Ying Han

submission deadline 20 Sep 2025 | 2 articles | Viewed by 13862 | Submission Open

Keywords: microbiota; dysbiosis; microbiota– gut– brain axis; short-chain fatty acid; immune pathway; vagus nerve; neuropsychiatric disorders; depression

(This special issue belongs to the Section Molecular Biology)

The Relationship, Mechanisms, and Treatment Strategies of Diabetes Mellitus and Related Diseases

edited by Maria Kokozidou

submission deadline 20 Sep 2025 | 5 articles | Viewed by 13740 | Submission Open

Keywords: diabetes mellitus; molecular mechanisms; related diseases; genetic basis; microRNAs; incretins; targeted therapies; immunotherapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Immunotherapy in Cancer: Molecular Basis and Novel Therapeutic Approaches

edited by Yonggu Lee

submission deadline 20 Sep 2025 | 7 articles | Viewed by 13287 | Submission Open

Keywords: cellular immunotherapy; adoptive immunotherapy; chimeric antigen receptor T-cell; epigenetic modulation; immunometabolism; microbiome; immune checkpoint inhibitor; cancer vaccine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Update on Immunotherapies for Cancer

edited by

Peter Johannes Holst

submission deadline 20 Sep 2025 | 4 articles | Viewed by 12745 | Submission Open

Keywords: cell therapies; monoclonal antibodies; molecular adjuvants; oncolytic therapies; immunogenic; chemotherapy and radiotherapy; cancer vaccines; immunodominance; neoantigens; clinical trials; tumor immune microenvironment

(This special issue belongs to the Section Molecular Oncology)

Advances in the Molecular Diagnosis and Treatment of Pancreatic Cancer

edited by Steven T. Brower and Robert Pergolizzi

submission deadline 20 Sep 2025 | 5 articles | Viewed by 11736 | Submission Open

Keywords: pancreatic cancer; molecular diagnostics; biomarkers; oncogenes; epigenetics; genomic profiling; next-generation sequencing; liquid biopsy; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Natural and Synthetic Compounds for Management, Prevention and Treatment of Obesity, 3rd Edition

edited by

Marianna Lauricella

and

Antonella D'Anneo

submission deadline 20 Sep 2025 | 4 articles | Viewed by 11627 | Submission Open

Keywords: obesity; adipokines; obesogens; genetic predisposition; natural/synthetic compounds; cardiovascular disorders; type II diabetes; non-alcoholic fatty liver disease; cancer

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Research in Breast Cancer: Pathophysiology and Treatment

edited by Costa Frangou

submission deadline 20 Sep 2025 | 6 articles | Viewed by 11509 | Submission Open

Keywords: breast; biomarker; early detection; immunotherapy; metastasis; microenvironment; outcomes; prognosis; relapse; treatment; tumor

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Effects of Bioactive Compounds in Oxidative Stress and Inflammation

edited by

Paul-Mihai Boarescu

and

Raluca Maria Pop

submission deadline 20 Sep 2025 | 6 articles | Viewed by 11169 | Submission Open

Keywords: natural products; antioxidant effects; anti-inflammatory effects; molecular targets; health beneficial effect; bioactive compounds

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Spermatogenesis and Male Infertility

edited by Wanxi Yang

submission deadline 20 Sep 2025 | 6 articles | Viewed by 10796 | Submission Open

Keywords: male reproduction; hormone regulation; blood– testis barrier; male reproductive diseases; male infertility

(This special issue belongs to the Section Molecular Biology)

Neurodegenerative Diseases: Molecular Mechanisms and Therapies, 3rd Edition

edited by

Zhidong Zhou

and

Alexandre Hiroaki Kihara

submission deadline 20 Sep 2025 | 4 articles | Viewed by 10387 | Submission Open

Keywords: neurodegeneration; neurodegenerative diseases; protein aggregation; pathogenesis; therapy; mitochondria; neuroinflammation; oxidative stress; cell therapy; clinical trial

(This special issue belongs to the Section Molecular Neurobiology)

The Emerging Role of Neutrophils in Cancer: Molecular Aspects of Plasticity and Potential Therapeutic Targets

edited by

Deepika Awasthi

submission deadline 20 Sep 2025 | 4 articles | Viewed by 10303 | Submission Open

Keywords: neutrophils; cancer; tumor microenvironment; tumor-associated neutrophils; innate immunity

(This special issue belongs to the Section Molecular Oncology)

Editorial Board Members’ Collection Series: Genome Stability

edited by

Tae-Hong Kang

and

Lasse Lindahl

submission deadline 20 Sep 2025 | 5 articles | Viewed by 10224 | Submission Open

Keywords: genome stability; DNA damage response; DNA repair; DNA replication; DNA recombination; ATR/ATM pathway; GENOTOXINS

(This special issue belongs to the Section Molecular Genetics and Genomics)

Metabolic Syndrome: New Insights in Pathogenesis, Diagnosis, Prevention, and Management

edited by

Lucia Maria Procopciuc

and

Roxana Liana Lucaciu

submission deadline 20 Sep 2025 | 7 articles | Viewed by 9791 | Submission Open

Keywords: insulin resistance; hypertension; diabetes mellitus; obesity; inflammation; stress; metabolic disorders; reproductive endocrine disorders; polycystic ovarian syndrome; waist circumference; estrogen deficiency; disturbances in adipose tissue; physical inactivity; overnutrition; cardiovascular diseases; abdominal obesity; genetics and epigenetics of metabolic syndrome; computational analysis

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular and Translational Research on Bone Tumors, 2nd Edition

edited by

Michela Rossi

and

Andrea Del Fattore

submission deadline 20 Sep 2025 | 2 articles | Viewed by 9697 | Submission Open

Keywords: primary bone tumours; metastatic bone tumour; therapy; biomarkers; epigenetic factors; immune-oncology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Biology and Hormonal Regulation in Reproductive Processes

edited by

Martin Stimpfel

and Helena Ban Frangež

submission deadline 20 Sep 2025 | 4 articles | Viewed by 9378 | Submission Open

Keywords: infertility; reproduction; embryos; genetics; epigenetics; signaling pathway; sperm; oocyte

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Tau Pathobiology in Neurodegenerative Diseases: From Molecular Mechanisms to Therapeutic Advances

edited by

Valentina Latina

and

Giuseppina Amadoro

submission deadline 20 Sep 2025 | 3 articles | Viewed by 9115 | Submission Open

Keywords: Alzheimer’ s disease; tauopathies; tau neurotoxicity; cellular and animal models; signaling pathways; tau-targeting therapies

(This special issue belongs to the Section Molecular Neurobiology)

102nd Anniversary of Neurotransmitter Discovery: Cholinergic Pathways in Physiology and Pathophysiology

edited by

Sumonto Mitra

submission deadline 20 Sep 2025 | 4 articles | Viewed by 8648 | Submission Open

Keywords: acetylcholine; physiological functions; pathological alterations; cholinergic pathways

(This special issue belongs to the Section Biochemistry)

The Zebrafish Model in Animal and Human Health Research, 2nd Edition

edited by

Antonella Marino Gammazza

and

Marta Anna Szychlinska

submission deadline 20 Sep 2025 | 6 articles | Viewed by 8070 | Submission Open

Keywords: zebrafish; environmental toxicology; predictive toxicology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mitochondrial Dysfunction: A Metabolic, Cardiovascular, Neurodegenerative and Neuromuscular Issue: 2nd Edition

edited by

Stefano Doccini

Federica Morani

and Claudia Nesti

submission deadline 20 Sep 2025 | 3 articles | Viewed by 7969 | Submission Open

Keywords: bioenergetics; mitochondrial disorders; biomarkers; OxPhos complexes; mitochondrial DNA; aging; neurodegenerative diseases; cardiovascular diseases; metabolic diseases; therapies to counteract mitochondrial dysfunction TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Bacteria

edited by

Giovanni Stelitano

submission deadline 20 Sep 2025 | 10 articles | Viewed by 7658 | Submission Open

Keywords: infections; bacteria; molecular biology; antimicrobials; bacterial enzymes; bioremediation

(This special issue belongs to the Section Molecular Microbiology)

State-of-the-Art Molecular Oncology in Brazil, 3rd Edition

edited by

Tiago Rodrigues

and

Roger Chammas

submission deadline 20 Sep 2025 | 4 articles | Viewed by 7358 | Submission Open

Keywords: apoptosis; autophagy; calcium; cancer; cell death; chemotherapy; metabolism; mitochondria; drug resistance; oxidative stress

(This special issue belongs to the Section Molecular Oncology)

Molecular Insight into the Processing and Characterization of Animal Fats and Vegetable Oils

edited by

Pavel Mokrejš

submission deadline 20 Sep 2025 | 4 articles | Viewed by 7354 | Submission Open

Keywords: lipid molecules; oils; fats; lipase; interesterification; hydrolysis; phospholipids; fatty acids; molecular research; nutrition; cosmetics matrices; medical applications; food; pharmacy; bioengineering; novel applications; biofuels

(This special issue belongs to the Section Molecular Biology)

Advances in Genetics of Human Reproduction

edited by

Jasenka Wagner

and

Borut Peterlin

submission deadline 20 Sep 2025 | 6 articles | Viewed by 7253 | Submission Open

Keywords: genetic; human reproduction; infertility; medically assisted reproduction; pregnancy complications; recurrent miscarriage

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Mechanisms of Plant Abiotic Stress Tolerance: 2nd Edition

edited by

Michael Moustakas

submission deadline 20 Sep 2025 | 6 articles | Viewed by 7194 | Submission Open

Keywords: acclimation; drought; salinity; pesticides; high– low temperature; high– low light intensity; nutrient deficiencies; heavy metals; UV radiation; photosynthetic efficiency; ROS; antioxidant mechanisms; redox regulation

(This special issue belongs to the Section Molecular Plant Sciences)

Zebrafish as a Model in Human Disease: 3rd Edition

edited by

Andrea Vettori

Nicola Facchinello

and

Marco G. Schiavone

submission deadline 20 Sep 2025 | 4 articles | Viewed by 7088 | Submission Open

Keywords: zebrafish; CRISPR/Cas9; transgenic lines; biosensors; endothelial cells; extracellular matrix; genetic mutant for human disease modeling; xenografts

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Editorial Board Members’ Collection Series: Pain

edited by

Sebastiano Mercadante

and

István Nagy

submission deadline 20 Sep 2025 | 3 articles | Viewed by 6870 | Submission Open

Keywords: cancer; inflammation; neuropathy; primary sensory neurons; spinal cord; brain

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Research in Spinal Cord Injury

edited by

Inbo Han

submission deadline 20 Sep 2025 | 3 articles | Viewed by 6834 | Submission Open

Keywords: spinal cord injury; molecular mechanisms; stem cell therapy; tissue engineering; neuroinflammation; neuroprotection; genetic regulation; epigenetics; therapeutic strategies

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research of Epithelial Function and Barrier Dysfunction

edited by Fariba Rezaee

submission deadline 20 Sep 2025 | 4 articles | Viewed by 6776 | Submission Open

Keywords: epithelial cells; actin cytoskeleton; viral infection; apical junctional complex; tight junction; adherens junction; barrier dysfunction; trans-epithelial electrical resistance; permeability; epithelial barrier

(This special issue belongs to the Section Molecular Immunology)

Mycotoxins, Immunity, and Inflammation

edited by

Yuseok Moon

submission deadline 20 Sep 2025 | 5 articles | Viewed by 6743 | Submission Open

Keywords: mycotoxin; immunity; inflammation; immunotoxicity; immunology

(This special issue belongs to the Section Molecular Toxicology)

Molecular Biology of Protein Kinases: Regulatory Mechanisms, Therapeutic Targets and Cancer Treatments

edited by Jaw Ji Yang

submission deadline 20 Sep 2025 | 2 articles | Viewed by 6658 | Submission Open

Keywords: protein kinases; signal transduction; cancer therapy; regulatory mechanisms; kinase inhibitors; therapeutic targets; molecular biology; structural biology; translational research; clinical applications

(This special issue belongs to the Section Molecular Biology)

Current Advances and Perspectives in Microbial Genetics and Genomics

edited by

Marcello Tagliavia

and Lucila Saavedra

submission deadline 20 Sep 2025 | 5 articles | Viewed by 6646 | Submission Open

Keywords: microbial genetics; genomics and metagenomics; gene regulation; microbe– host interactions; adaption and resistance mechanisms; microbial metabolism

(This special issue belongs to the Section Molecular Microbiology)

The Role and Mechanism of P2X7 Receptor in Cancer and Inflammatory Diseases

edited by

Anna Lisa Giuliani

submission deadline 20 Sep 2025 | 3 articles | Viewed by 6540 | Submission Open

Keywords: P2X7 receptor; inflammation; cancer; purinergic signalling

(This special issue belongs to the Section Molecular Immunology)

Advanced Research of Metallic Nanoparticles

edited by

Edyta Proniewicz

submission deadline 20 Sep 2025 | 3 articles | Viewed by 6506 | Submission Open

Keywords: metallic nanoparticles (MNPs); biosensors; synthesis methods; molecular spectroscopy characteristic; molecular medicine; molecular biology

(This special issue belongs to the Section Molecular Nanoscience)

Boosting the Production of Bioactive Compounds: Biotechnology and Metabolic Engineering of Medicinal Plants

edited by

Katarzyna Hnatuszko-Konka

and

Izabela Grzegorczyk-Karolak

submission deadline 20 Sep 2025 | 5 articles | Viewed by 6285 | Submission Open

Keywords: bioactive compounds; plant tissue culture; elicitors; metabolic engineering; gene expression; medicinal plants; metabolic pathway; plant biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms and Pathophysiology of Sepsis

edited by

Vlad Pădureanu

submission deadline 20 Sep 2025 | 5 articles | Viewed by 6273 | Submission Open

Keywords: animal models; therapeutic concepts; biomarkers; sepsis; immune suppression; epigenetics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Role of Natural Compounds in Human Health and Disease

edited by Jaewon Shim and

Wook-bin Lee

submission deadline 20 Sep 2025 | 5 articles | Viewed by 6221 | Submission Open

Keywords: natural compound; therapeutic applications; action mechanisms of natural compounds; traditional medicine

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Advances and Insights into Liver Diseases

edited by

Jacek Baj

submission deadline 20 Sep 2025 | 4 articles | Viewed by 6205 | Submission Open

Keywords: liver; hepatocellular carcinoma; cancer; hepatitis; cirrhosis; encephalopathy; non-alcoholic fatty liver disease; autoimmune diseases; Wilson’ s disease; fatty liver disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insights into Anti-cancer Drug Discovery and Development

edited by

Ki-cheong Park

submission deadline 20 Sep 2025 | 3 articles | Viewed by 6196 | Submission Open

Keywords: anti-cancer drug resistant; cancer recurrence; cancer metastasis; cancer stem cells; target validation; target identification; metabolic reprogramming of cancer stem cells; unmet medical needs

(This special issue belongs to the Section Molecular Pharmacology)

Viral Infections and Immune Responses

edited by

Alessandra Ruggiero

and

Marco Iannetta

submission deadline 20 Sep 2025 | 4 articles | Viewed by 6056 | Submission Open

Keywords: virus; infections; immune response; T-cells; B-cells; antibodies; neutralizing activity

(This special issue belongs to the Section Molecular Immunology)

The Biochemistry, Molecular and Cell Biology Beyond Flowers

edited by

Isabel Marques

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5929 | Submission Open

Keywords: flowers; homeotic genes; MADSBox; molecular expression; pollination; stress; transcription factors

(This special issue belongs to the Section Molecular Plant Sciences)

State-of-the-Art Molecular Immunology in Chile, 2nd Edition

edited by

Marcela Hernandez Ríos

Juan C. Aguillon

, María Rosa Bono,

Nicolas Dutzan

Rolando Vernal

and

Leandro J. Carreño

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5919 | Submission Open

Keywords: innate immunity; adaptive immunity; host– pathogen interactions; immunopathology; osteoimmunology; immunosenescence; immunotherapy; antibody; vaccines; Chile

(This special issue belongs to the Section Molecular Immunology)

Displaying special issue 2101-2150 on page 43 of 69.

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