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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Advances in Wound Healing: 3rd Edition

edited by

Alina Maria Holban

and

Carmen Curutiu

submission deadline 31 Jan 2027 | Viewed by 223 | Submission Open

Keywords: management of wounds; nanobiomaterials; infection control; chronic wounds; biofilm infections; wound dressings; tissue engineering; wound healing

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in Quantum Neuroactivity

edited by

Mihai V. V. Putz

submission deadline 31 Jan 2027 | Viewed by 218 | Submission Open

Keywords: neurosciences; neurochemistry; neurobiology; quantum theory and computation; neuromorphisms; QSAR (quantitative structure-activity relationships); bio- and nano-materials; (artificial) neural networks.

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms of DNA Replication and Repair

edited by Sneha Saxena

submission deadline 31 Jan 2027 | Viewed by 200 | Submission Open

Keywords: DNA replication; DNA repair; replication stress response; genomic instability; DNA damage response

(This special issue belongs to the Section Molecular Genetics and Genomics)

Metalloproteins in Biomedicine: From Molecular Mechanisms and Biomarkers to Diagnostics, Therapeutics and Nanotechnology

edited by

Kamil Gareev

and

Maxim Shevtsov

submission deadline 31 Jan 2027 | Viewed by 197 | Submission Open

Keywords: metalloproteins; biomarkers; nanomedicine; immunology; molecular mechanisms; nanotechnology; biosensing

(This special issue belongs to the Section Biochemistry)

State-of-the-Art Molecular Neurobiology in Turkey

edited by Bilal Çiğ, Atay Vural and Aydan Köysüren

submission deadline 31 Jan 2027 | Viewed by 183 | Submission Open

Keywords: molecular neurobiology; ion channels; neurophysiology; neuropharmacology; neuroinflammation; neurodegeneration; glia biology; synaptic signaling; oxidative stress; translational neuroscience

(This special issue belongs to the Section Molecular Neurobiology)

Mitochondrial Dysfunction and Chronic Diseases: Molecular Insight and Therapeutic Opportunities

edited by

Manivannan Yegambaram

submission deadline 31 Jan 2027 | Viewed by 180 | Submission Open

Keywords: mitochondrial dysfunction; redox signaling; metabolism; mitochondrial dynamics; mitochondrial-targeted therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research in Biochar

edited by

Muhammad Kashif Irshad

submission deadline 31 Jan 2027 | Viewed by 172 | Submission Open

Keywords: engineered biochar; molecular mechanisms; surface complexation; heavy metal(loid) immobilization; PFAS; microplastics; colloid-facilitated transport; spectroscopic characterization; density functional theory; machine learning; soil microbiology

(This special issue belongs to the Section Materials Science)

Mechanism of SARS-CoV-2 Interactions with Tissue Cells

edited by Matias Nunes Frizzo and

Monica Gelzo

submission deadline 31 Jan 2027 | Viewed by 167 | Submission Open

Keywords: SARS‑CoV‑2; virus–cell interaction; viral pathogenesis; immune response; inflammation and tissue injury; clinical and laboratory biomarkers

(This special issue belongs to the Section Molecular Immunology)

Mechanisms of Cardiotoxicity in Anticancer Therapies

edited by Sheetalnath Rooge

submission deadline 31 Jan 2027 | Viewed by 167 | Submission Open

Keywords: cardiotoxicity; cardiac hypertrophy; mitochondrial dysfunction; immune response; autophagy; mitophagy; lipophagy; apoptosis; ferroptosis; DNA damage; iron overload; lipid peroxidation; ROS production; Ca2+ homeostasis; microRNA

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pseudopeptidases: From Structure to Function in Health and Disease

edited by

Elena N. Elpidina

and

Yakov E. Dunaevsky

submission deadline 31 Jan 2027 | Viewed by 159 | Submission Open

Keywords: pseudopeptidases; pseudoenzymes; inactive homologs of peptidases; peptidases; protein structure; protein function

(This special issue belongs to the Section Biochemistry)

Ventricular Function and Pathophysiology in Cardiovascular Diseases

edited by

Filip Konecny

submission deadline 31 Jan 2027 | Viewed by 159 | Submission Open

Keywords: heart failure; ventricular function; pressure–volume analysis; cardiac hemodynamics; ventricular remodeling; cardiovascular pathophysiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Acute Kidney Injury: From Pathogenesis to Targeted Therapy

edited by

Milan Ivanov

submission deadline 31 Jan 2027 | Viewed by 159 | Submission Open

Keywords: AKI; pathogenesis; biomarkers; targeted therapy; ischemia–reperfusion injury; inflammation; apoptosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Medicinal Chemistry: Design, Synthesis and Application

edited by

Vasilii Otvagin

submission deadline 31 Jan 2027 | Viewed by 154 | Submission Open

Keywords: medicinal chemistry; drug design; synthesis and analysis; biological chemistry; bioactive natural products

(This special issue belongs to the Section Molecular Pharmacology)

Genomics and Molecular Mechanisms of Cancer

edited by

Raffaella Lazzarini

submission deadline 31 Jan 2027 | Viewed by 153 | Submission Open

Keywords: carcinogenesis; genetic and epigenetic alterations; cancer molecular mechanisms; cancer regulatory networks

(This special issue belongs to the Section Molecular Oncology)

In Silico and In Vitro Advancements in Natural-Product-Derived Therapeutics

edited by

Ploenthip Puthongking

submission deadline 31 Jan 2027 | Viewed by 148 | Submission Open

Keywords: biological activity of natural products; natural product chemistry; traditional medicine; molecular docking; network pharmacology; machine learning; in vitro/in vivo experiments

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advanced Functional Materials for Electrochemical Energy Conversion and Storage

edited by

Mohammad R. Thalji

and

Farzaneh Mahmoudi

submission deadline 31 Jan 2027 | Viewed by 142 | Submission Open

Keywords: advanced functional materials; molecular design; electrochemical energy conversion; energy storage; electrocatalysis; hydrogen/oxygen production; batteries; supercapacitors; interface/molecular engineering; charge-transfer mechanisms

(This special issue belongs to the Section Materials Science)

Bioactive Potentials of Phytochemicals: Anti-Inflammatory, Antibacterial, and Antitoxic Functions

edited by

Juliana Felix-Silva

submission deadline 31 Jan 2027 | Viewed by 142 | Submission Open

Keywords: phytochemicals; natural products; anti-inflammatory activity; antibacterial activity; antitoxic activity; anti-venom activity; molecular mechanisms; oxidative stress; bioactive compounds; drug discovery

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Gastrointestinal Injury and Inflammation: Molecular Mechanisms and Therapeutic Insights

edited by Rei Kawashima

submission deadline 31 Jan 2027 | Viewed by 142 | Submission Open

Keywords: gastrointestinal mucosa; mucosal injury; intestinal inflammation; mucosal immunity; epithelial barrier; mucin; goblet cells; mechanosensing; host–microbiota interactions; therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Hydrogel Materials for Regenerative Medicine: Molecular Perspectives

edited by

Yiran Li

submission deadline 31 Jan 2027 | Viewed by 138 | Submission Open

Keywords: supramolecular hydrogels; adaptive materials; biomimetic material; stimuli-responsive hydrogels; tissue engineering; regenerative medicine; phase separation hydrogel

(This special issue belongs to the Section Materials Science)

Molecular Insights into Hepatocellular Carcinoma: Mechanisms, Therapeutics and Liver Transplantation

edited by

Kevin Tak-Pan Ng

submission deadline 31 Jan 2027 | Viewed by 136 | Submission Open

Keywords: hepatocarcinogenesis; molecular pathogenesis; tumor microenvironment; metabolic dysfunction-associated fatty liver disease (MAFLD); metastasis; genetic and epigenetic alterations; biomarkers; precision oncology; targeted therapy; immunotherapy; therapy resistance; immune escape; tumor recurrence; transplant oncology

(This special issue belongs to the Section Molecular Oncology)

Medicinal Plants and Natural Products: Molecular Mechanisms and Therapeutic Applications

edited by

Mary Anne Medeiros Bandeira

submission deadline 31 Jan 2027 | Viewed by 135 | Submission Open

Keywords: medicinal plants; natural products; phytochemicals; molecular pharmacology; signal transduction; bioactive compounds; oxidative stress; inflammation; drug discovery; translational medicine

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Metabolomics for Environmental Exposure and Toxicological Research

edited by

Churdsak Jaikang

and Hataichanok Chuljerm

submission deadline 31 Jan 2027 | Viewed by 130 | Submission Open

Keywords: toxicology; metabolomics; environmental health; chemical exposure; biomarkers; environmental metabolomics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Mechanisms of Renal Injury

edited by

Cristián A. Amador

and

Alexis A. Gonzalez

submission deadline 31 Jan 2027 | Viewed by 129 | Submission Open

Keywords: renal inflammation; kidney damage and exercise; tubular injury; glomerular disease; oxidative stress; kidney repair and regeneration; immune–kidney interactions; biomarkers of kidney disease

(This special issue belongs to the Section Molecular Biology)

Molecular Epidemiology and Pathogenesis of Critical Gram-Negative Pathogens

edited by

Zakuan Zainy Deris

and

Mohd Zulkifli Salleh

submission deadline 31 Jan 2027 | Viewed by 129 | Submission Open

Keywords: Gram-negative bacteria; antimicrobial resistance mechanisms; genomic surveillance; biofilm formation; structural biology; molecular diagnostics; host–pathogen interactions; One Health

(This special issue belongs to the Section Molecular Microbiology)

Recent Advances in Exercise Physiology and Human Performance

edited by

Adrián De La Rosa

submission deadline 31 Jan 2027 | Viewed by 129 | Submission Open

Keywords: exercise physiology; exercise training; sports nutrition; molecular adaptations; oxidative stress and redox biology; recovery; human performance

(This special issue belongs to the Section Molecular Biology)

Role of Lipids in Sarcopenia and Atrophy of Skeletal Muscle

edited by Sara Baldelli and

Serena Castelli

submission deadline 31 Jan 2027 | Viewed by 129 | Submission Open

Keywords: sarcopenia; skeletal muscle atrophy; lipid metabolism; oxidative stress

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Epithelial Dysfunction in Allergic Diseases

edited by

Sena Ardicli

submission deadline 31 Jan 2027 | Viewed by 128 | Submission Open

Keywords: epithelial dysfunction; epithelial barrier theory; allergic diseases; barrier integrity; immune-epithelial crosstalk; type 2 inflammation; mucosal immunology; environmental exposures; tissue remodeling; translational allergy research

(This special issue belongs to the Section Molecular Immunology)

AI-Powered Precision Nanomedicine for Brain Delivery

edited by João Dias-Ferreira

submission deadline 31 Jan 2027 | Viewed by 128 | Submission Open

Keywords: neuroscience; glioblastoma; AI-driven healthcare; nanotargeted drug delivery; central nervous system; genic edition and therapy

(This special issue belongs to the Section Molecular Pharmacology)

Nutritional Interventions and Metabolic Studies in Diabetes

edited by Sreelakshmi Sankara Narayanan

submission deadline 31 Jan 2027 | Viewed by 127 | Submission Open

Keywords: diabetes mellitus; nutritional interventions; metabolic health; functional foods and nutraceuticals; omics approaches; advanced glycation end products (AGEs)

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Pathophysiology and Therapeutic Targets in Cardiovascular Disease

edited by Adrijan Sarajlija and

Nikola Ilić

submission deadline 31 Jan 2027 | 1 articles | Viewed by 125 | Submission Open

Keywords: cardiovascular disease; pathophysiology; therapeutic targets; precision medicine; cardiomyopathy; heart failure; vascular biology; genetics; artificial intelligence; translational cardiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms Governing Immune Regulation and Tumor Suppression in Cancer

edited by

Cleber Machado-Souza

submission deadline 31 Jan 2027 | Viewed by 123 | Submission Open

Keywords: tumor suppression; immune regulation; cancer signaling; tumor microenvironment; epigenetics; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Vaccine Immunology Research in Veterinary Medicine

edited by

Yue Zhang

submission deadline 31 Jan 2027 | Viewed by 120 | Submission Open

Keywords: veterinary vaccines; vaccine immunology; nanoparticle vaccines; animal infectious diseases; adjuvants; antigen delivery

(This special issue belongs to the Section Molecular Immunology)

Molecular and Cellular Mechanisms in Skin Endocrinology and Dermatology

edited by

Terrence Piva

and

Beatrice Bălăceanu-Gurău

submission deadline 31 Jan 2027 | Viewed by 119 | Submission Open

Keywords: skin endocrinology; molecular dermatology; hormonal signaling; skin aging; inflammatory dermatoses; skin microbiome; cutaneous immune response; esthetic and regenerative dermatology; oncodermatology; nanocarrier-based drug delivery

(This special issue belongs to the Section Molecular Biology)

Phyto-Functional Nanomaterials: Synthesis, Characterization and Application, 2nd Edition

edited by

Maria G. P. M. S. Neves

Carla Isabel Madeira dos Santos

and

Nuno M. M. Moura

submission deadline 31 Jan 2027 | Viewed by 118 | Submission Open

Keywords: phyto-functional nanomaterials; green synthesis; hydrogen generation; pollutant degradation/removal; fine chemistry; photoinactivation; cancer; microorganisms

(This special issue belongs to the Section Molecular Nanoscience)

Advances and Applications of Gold Nanotherapeutics

edited by

Anand Thirupathi

submission deadline 31 Jan 2027 | Viewed by 117 | Submission Open

Keywords: gold nanoparticles (AuNPs) and nanotheranostics; oxidative stress; ROS-mediated signaling; redox-mediated signaling; physical exercise and exerkines; low-intensity pulsed ultrasound; redox homeostasis and mitochondrial function; neuroplasticity; neurodegenerative diseases; cardiac diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Volatile Organic Compound Detection and Analysis

edited by Velmurugan Thavasi

submission deadline 31 Jan 2027 | Viewed by 117 | Submission Open

Keywords: volatile organic compounds; VOC analysis; chemical sensors; mass spectrometry; gas chromatography; breathomics; volatilomics; molecular biomarkers; chemometrics; AI/ML

(This special issue belongs to the Section Biochemistry)

Physicochemical Properties and Applications of Nanomaterials in Biology and Medicine: 2nd Edition

edited by

Gangho Lee

submission deadline 31 Jan 2027 | Viewed by 116 | Submission Open

Keywords: nanoparticles; nanomaterials; biomedicine; synthesis; physicochemical properties; imaging; therapy; contrast agents; therapeutic agents

(This special issue belongs to the Section Molecular Nanoscience)

Physiological and Molecular Mechanisms of Fruit Growth, Development and Ripening

edited by

Orhan Karakaya

submission deadline 31 Jan 2027 | Viewed by 112 | Submission Open

Keywords: fruit development; fruit ripening; plant physiology; gene expression; metabolomics; hormonal regulation; postharvest biology; fruit quality; abiotic stress; molecular mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

Design and Evaluation of Metal-Based Anticancer Drugs and Crucial Peptide Inhibitors

edited by

Sujoy Das

submission deadline 31 Jan 2027 | Viewed by 111 | Submission Open

Keywords: metal-based drugs; anticancer agents; peptide inhibitors; medicinal chemistry; drug discovery; enzyme inhibitors; peptide inhibitors; structure–activity relationship

(This special issue belongs to the Section Molecular Pharmacology)

Glutathione Deficiency and Health Conditions

edited by Vishwanath Venketaraman

submission deadline 31 Jan 2027 | Viewed by 111 | Submission Open

Keywords: neurological disorders; neurodegenerative diseases; ARDS; COPD; aging; cancer; diabetes; glutathione; HIV; tuberculosis

(This special issue belongs to the Section Biochemistry)

The Latest Computational Models in Oncology: From Tumor Initiation to Progression to Treatment

edited by Cecilia Ana Suárez

submission deadline 31 Jan 2027 | Viewed by 111 | Submission Open

Keywords: cancer; computational oncology; multiscale modeling; systems biology; multi-omics; tumor dynamics; deep medical radiomics; hybrid computational frameworks; digital twins; precision oncology

(This special issue belongs to the Section Molecular Oncology)

Anticancer Potential of Natural Products: Molecular Insights and Therapeutic Perspectives

edited by

Nunzio Antonio Cacciola

, Annunziata Corteggio and

Daniela Melillo

submission deadline 31 Jan 2027 | Viewed by 110 | Submission Open

Keywords: natural products; bioactive compounds; anticancer; tumour microenvironment; cancer prevention and therapy

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Multi-Omics and Molecular Networks in Cardiometabolic Medicine

edited by

Andreas Leiherer

submission deadline 31 Jan 2027 | Viewed by 108 | Submission Open

Keywords: cardiometabolic diseases; multi-omics integration; molecular biomarkers; lipidomics; metabolomics; molecular pathophysiology; machine learning; bioinformatics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Advances in Toxicity and Genotoxicity Screening of Environmental Stressors

edited by

Karolina Sunjog

submission deadline 31 Jan 2027 | Viewed by 108 | Submission Open

Keywords: environmental stressors; toxicity; genotoxicity; environmental pollutants; emerging contaminants; in vitro models; in vivo models; biomarker analysis; environmental risk assessment

(This special issue belongs to the Section Molecular Toxicology)

Synthetic Lethality and Genome Stability in Cancer: From Molecular Mechanisms to Precision Therapy

edited by Sandra Bell

submission deadline 31 Jan 2027 | Viewed by 107 | Submission Open

Keywords: synthetic lethality; DNA repair; PARP inhibitors; genome instability; therapeutic resistance mechanisms; replication stress; DNA damage response; targeted therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Glucose in Energy Metabolism: Molecular Perspectives

edited by

Luis Alberto Madrigal-Perez

submission deadline 31 Jan 2027 | Viewed by 101 | Submission Open

Keywords: insulin signaling; metabolic flexibility; oxidative phosphorylation; cellular energetics; metabolic disorders; glucose sensing; ATP production; metabolomics; diabetes; nutrient sensing

(This special issue belongs to the Section Biochemistry)

Novel Chemical Compounds and Natural Modulators in Anticancer Therapy: Synthesis, Biological Activity, and Mechanisms of Action

edited by

Mateusz Kciuk

and

Damian Kołat

submission deadline 31 Jan 2027 | Viewed by 99 | Submission Open

Keywords: anticancer therapy; medicinal chemistry; natural products; synthetic compounds; biological activity; molecular mechanisms; drug discovery; cancer signaling; structure–activity relationship; drug resistance

(This special issue belongs to the Section Molecular Oncology)

Inflammatory Bowel Disease and Microbiome: 2nd Edition

edited by

Abigail Raffner

, Paola Menghini and

Drishtant Singh

submission deadline 31 Jan 2027 | Viewed by 98 | Submission Open

Keywords: inflammatory bowel disease; Crohn’s disease; ulcerative colitis; gut microbiota; diet; treatment; pathogenesis; biomarker

(This special issue belongs to the Section Molecular Microbiology)

AI-Facilitated Drug Discovery Against Membrane Ion Channels

edited by

Jian Shi

submission deadline 31 Jan 2027 | Viewed by 97 | Submission Open

Keywords: artificial intelligence; membrane ion channel; drug development; drug design; drug synthesis

(This special issue belongs to the Section Molecular Pharmacology)

Algal Biotechnology for Circular Bioeconomy: Molecular Advances and Sustainable Applications

edited by

Ramachandran Sivaramakrishnan

submission deadline 31 Jan 2027 | Viewed by 97 | Submission Open

Keywords: algal biotechnology; microalgae; macroalgae; seaweed; molecular biology; genomics; transcriptomics; metabolomics; proteomics; synthetic biology; genetic engineering; metabolic engineering; algal biorefineries; bioactive compounds; phytochemicals; high-value metabolites; natural products; nutraceuticals; bioproducts; biomass valorization; circular bioeconomy; sustainable biotechnology; environmental remediation; carbon capture; biofuels; omics technologies; algal cultivation; systems biology; marine biotechnology; blue biotechnology

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 2101-2150 on page 43 of 65.

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