International Journal of Molecular Sciences

International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Metabolic Dynamics and Immune Surveillance in the Tumor Microenvironment

edited by

Jyoti Kaushal

submission deadline 20 Feb 2026 | Viewed by 192 | Submission Open

Keywords: cancer; TME; metabolism; immune cells; signaling pathway; therapy

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

The Roles of Oxidative Stress in Metabolic Syndrome

edited by

Maria Magdalena Quetglas-Llabrés

and

Margalida Monserrat-Mesquida

submission deadline 20 Feb 2026 | Viewed by 191 | Submission Open

Keywords: oxidative stress; metabolic syndrome; inflammation; antioxidants; human chronic diseases; cardiometabolic diseases; nutrition; lifestyle

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Molecular Research in Brain Tumors

edited by

Shiv K. Gupta

submission deadline 20 Feb 2026 | Viewed by 190 | Submission Open

Keywords: targeted therapy; blood– brain barrier; GBM; glioma; immune checkpoint blockers; TME

(This special issue belongs to the Section Molecular Oncology)

Advances in Ferrocene-Based Molecular Research: Synthesis, Properties, and Applications

edited by

Mojca Čakić Semenčić

submission deadline 20 Feb 2026 | Viewed by 188 | Submission Open

Keywords: ferrocene; organometallic chemistry; bioorganometallic chemistry; ferrocene derivatives; synthesis; applications; bioconjugates

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Neurodegenerative Disorders: Advances in Mechanisms, Models, and Therapeutics

edited by Craig Bennett

submission deadline 20 Feb 2026 | Viewed by 188 | Submission Open

Keywords: TDP-43; C9orf72; dipeptide repeat; proteotoxicity; cryptic exon exclusion; L-BMAA

(This special issue belongs to the Section Molecular Neurobiology)

Degradable Polymers: Synthesis, Applications, and Environmental Impact

edited by Ce Sun and

Haiyang Gao

submission deadline 20 Feb 2026 | Viewed by 186 | Submission Open

Keywords: degradable polymer; synthesis; degradation mechanisms; sustainability

(This special issue belongs to the Section Macromolecules)

Gene Mining and Germplasm Innovation for the Important Traits in Rice (Second Edition)

edited by

Shimin Zuo

and

Yongmei Bao

submission deadline 20 Feb 2026 | Viewed by 179 | Submission Open

Keywords: rice; gene mining; important traits; molecular design; gene editing; germplasm innovation

(This special issue belongs to the Section Molecular Plant Sciences)

Synthesis and Transformations of Bioactive Cyclic Imides

edited by

István Szatmári

submission deadline 20 Feb 2026 | Viewed by 170 | Submission Open

Keywords: PROTAC; phthalimides; maleimides; cyclic imides; targeted protein degradation; protein labeling; antibody–drug conjugates; drug design and synthesis; drug conjugation

(This special issue belongs to the Section Biochemistry)

Molecular Forensics at Trial

edited by

Guido Viel

submission deadline 20 Feb 2026 | Viewed by 169 | Submission Open

Keywords: forensic science; molecular biology; evidence; proof; justice; trial; forensic pathology; forensic genetics; forensic histology; forensic toxicology

(This special issue belongs to the Section Molecular Toxicology)

Advancing Mycorrhizal Research for Promoting Plant Growth Under Abiotic Stress

edited by