Submit to IJMS Review for IJMS Propose a Special Issue

Journal Menu

Journal Browser

Special Issues

International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section

Search by Title/Keyword

Order results

Display

Results per page

Molecular Docking Studies and Enzyme Inhibitory Assessment of Synthesized Heterocyclic Compounds

edited by

Mohamed Maatallah

submission deadline 31 Oct 2026 | Viewed by 247 | Submission Open

Keywords: heterocyclic compounds; molecular docking; enzyme inhibition; structure activity relationships (SAR); synthetic medicinal chemistry; computational chemistry; in silico drug design; ADMET prediction; molecular dynamics simulation

(This special issue belongs to the Section Biochemistry)

Microplastics and Nanoplastics: Cellular Toxicity and Health Implications

edited by Gaetana Gambino

submission deadline 31 Oct 2026 | Viewed by 246 | Submission Open

Keywords: microplastics (MPs); nanoplastics (NPs); cellular toxicity; human health; oxidative stress; inflammation; genotoxicity; mitochondrial; dysfunction; bioaccumulation; mechanistic toxicology

(This special issue belongs to the Section Molecular Toxicology)

Heart Diseases: Molecular Research and Novel Therapies

edited by Monika M. Gladka

submission deadline 31 Oct 2026 | Viewed by 243 | Submission Open

Keywords: cardiovascular diseases; molecular mechanisms; cardiac remodeling; heart failure; gene regulation; epigenetics; non-coding RNA; inflammation; regenerative medicine; novel therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Effects and Applications of Nanoparticles in Plant-Pathogen Interactions and Plant Physiology

edited by

Solabomi Olaitan Ayoade

submission deadline 31 Oct 2026 | Viewed by 242 | Submission Open

Keywords: plant–pathogen interaction; nanotechnology; plant physiology; transcriptomics; DNA methylation; antimicrobial mechanism; metabolomics; microbial structure analysis

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Resistance to Targeted Cancer Therapies

edited by

Patrick Ming-Kuen Tang

and

Dongmei Zhang

submission deadline 31 Oct 2026 | Viewed by 241 | Submission Open

Keywords: cancer therapy; drug resistance; molecular mechanism; artificial intelligence; singel-cell bioinformatics; spatial analysis

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms of Environment-Induced Human Diseases

edited by

Halim İşsever

submission deadline 31 Oct 2026 | Viewed by 240 | Submission Open

Keywords: environmental exposures; heavy metal toxicity; environment-induced human diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into Cancer Biomarkers and Targeted Therapies in Solid Tumors

edited by Michele Ghidini

submission deadline 31 Oct 2026 | Viewed by 240 | Submission Open

Keywords: cancer biomarkers; target therapies; solid tumors; mutations; molecular biology; immunotherapy; TKI inhibitors; monoclonal antibodies; NGS; molecular panel

(This special issue belongs to the Section Molecular Oncology)

Immune Crosstalk Between Host and Pathogens

edited by

Ulrike Kemmerling

and

Christian Castillo

submission deadline 31 Oct 2026 | Viewed by 236 | Submission Open

Keywords: host-pathogen interactions; virus; bacteria; parasites; innate immunity; adaptive immunity, signal transduction; immune evasion; cytokines; inflammation

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms and Therapeutic Approaches in Glaucoma and Retinal Neurodegeneration

edited by Yukihiro Shiga

submission deadline 31 Oct 2026 | Viewed by 235 | Submission Open

Keywords: glaucoma; retinal neurodegeneration; retinal ganglion cells; mitochondrial dysfunction; neuroinflammation; neuro-glial interactions; multi-omics; biomarkers; disease-modifying therapies; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Molecules for Advanced Biosensors for Health, Food Safety and Environment

edited by

Sabato D’Auria

, Piotr Bojarski and Beata Wielgus-Kutrowska

submission deadline 31 Oct 2026 | Viewed by 232 | Submission Open

Keywords: proteins; electrochemistry; biosensors; molecular diagnostics; food safety; environmental monitoring

(This special issue belongs to the Section Biochemistry)

Calcium Channel Signaling: From Molecular Structure to Physiological Function

edited by

Dongki Yang

submission deadline 31 Oct 2026 | Viewed by 230 | Submission Open

Keywords: calcium signaling; ion channels; cell signaling; intracellular signaling; membrane proteins; electrophysiology; structural biology; cryo-electron microscopy; protein structure–function; signal transduction; calcium homeostasis; cellular physiology; molecular mechanisms; imaging techniques; live-cell imaging; systems biology; computational biology; pharmacology; drug discovery; therapeutic targets; translational research; disease mechanisms; cardiovascular diseases; neurological disorders; neurodegeneration; cancer biology; metabolism; inflammation; stem cells

(This special issue belongs to the Section Molecular Biology)

Antiviral Immune Responses and Mechanisms

edited by Xueqing Ma

submission deadline 31 Oct 2026 | Viewed by 230 | Submission Open

Keywords: antiviral immunity; immune response; molecular mechanism; animal virus; innate immunity; adaptive immunity; immune escape; veterinary infectious diseases

(This special issue belongs to the Section Molecular Immunology)

The Effects of Dietary Factors and Nutrition on Chronic Disease

edited by

Zaidatul Akmal Othman

and

Zaida Zakaria

submission deadline 31 Oct 2026 | Viewed by 229 | Submission Open

Keywords: dietary patterns; chronic disease prevention; functional foods and bioactive compounds; nutritional epidemiology; gut microbiota; metabolic health

(This special issue belongs to the Section Bioactives and Nutraceuticals)

The Basic Mechanisms of Brain Inflammation

edited by

Diogo Dominguini

submission deadline 31 Oct 2026 | Viewed by 229 | Submission Open

Keywords: health sciences; neuroscience; pathophysiology; cognitive impairment; inflammation; mental health; oxidative stress

(This special issue belongs to the Section Molecular Immunology)

Molecular Biomarkers and AI in Cardiac Electrophysiology

edited by Kenneth C. Bilchick

submission deadline 31 Oct 2026 | Viewed by 228 | Submission Open

Keywords: cardiac electrophysiology; molecular biomarkers; artificial intelligence; machine learning; atrial fibrillation; ventricular arrhythmia; sudden cardiac death; electrocardiography (ECG); cardiac imaging; precision medicine

(This special issue belongs to the Section Molecular Biology)

Nanoparticle-Mediated Molecular Regulation of Plant Tolerance

edited by

Abolghassem Emamverdian

and

James Barker

submission deadline 31 Oct 2026 | Viewed by 228 | Submission Open

Keywords: nanomaterials; plant stress physiology; antioxidant defense system; abiotic stress; molecular signaling; reactive oxygen species (ROS); phytoremediation; gene expression regulation; nutrient uptake; sustainable agriculture

(This special issue belongs to the Section Molecular Nanoscience)

Precision Medicine and Rare Cancers

edited by Juha Rantala

submission deadline 31 Oct 2026 | Viewed by 226 | Submission Open

Keywords: precision medicine; rare cancers; biomarkers; targeted therapies; tumor models; drug repurposing; ex vivo drug screening

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

T-Cell Function and Molecular Regulation

edited by

Davide Raineri

and

Hugo Abreu

submission deadline 31 Oct 2026 | Viewed by 224 | Submission Open

Keywords: T-cell activation and differentiation; immune checkpoints; signaling pathways; epigenetic modifications; immune tolerance; T-cell exhaustion; adoptive immunotherapy; cytokine signaling

(This special issue belongs to the Section Molecular Immunology)

Insights of Metabolomics

edited by

Xiaopeng Chen

submission deadline 31 Oct 2026 | Viewed by 224 | Submission Open

Keywords: pathway; metabolites; metabolomics; LC; GC; NMR; mechanism; statistical analysis

(This special issue belongs to the Section Biochemistry)

Integrative Genetic and Multi-Omics Approaches to Disease Biology

edited by

Emmanuel Adewuyi

submission deadline 31 Oct 2026 | Viewed by 224 | Submission Open

Keywords: disease genes; human genomics; GWAS; multi-omics; regulatory genomics; mendelian randomisation; gene prioritisation; pleiotropy; precision medicine; translational genetics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Mechanisms of Anesthetic Effects

edited by Jose Luis Guerrero Orriach

submission deadline 31 Oct 2026 | Viewed by 223 | Submission Open

Keywords: general anesthetics; molecular pharmacology; ion channels; gaba receptors; neuroprotection; signal transduction; mitochondrial dysfunction; local anesthetics; anesthetic-induced neurotoxicity; proteomic

(This special issue belongs to the Section Molecular Biology)

Unveiling Bioactive Marine Compounds

edited by

Noora Barzkar

submission deadline 31 Oct 2026 | Viewed by 223 | Submission Open

Keywords: marine natural products; bioactive compounds; molecular diversity; biosynthetic gene clusters; combinatorial biosynthesis; drug discovery

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Exercise and Immunopathology

edited by Rodolfo de Paula Vieira and Luis Vicente Franco Oliveira

submission deadline 31 Oct 2026 | Viewed by 222 | Submission Open

Keywords: exercise immunology; exercise physiology; inflammation; immune response; cardiopulmonary diseases; exercise rehabilitation; immune modulation; chronic diseases; aging and exercise; sports physiology

(This special issue belongs to the Section Molecular Immunology)

Plant–Fungal Disease Interactions: Pathogenesis, Epidemiology, and Management

edited by

Sibel Derviş

and

Muharrem Türkkan

submission deadline 31 Oct 2026 | Viewed by 215 | Submission Open

Keywords: plant–fungal interactions; fungal pathogenesis; disease epidemiology; virulence mechanisms; soilborne pathogens; postharvest diseases; biological control; sustainable disease management; oomycetes; population genetics

(This special issue belongs to the Section Molecular Plant Sciences)

The State of the Art in Immuno-Oncology: What to Do with Glioblastoma?

edited by Silvina Lompardía

submission deadline 31 Oct 2026 | Viewed by 214 | Submission Open

Keywords: glioblastoma; CNS malignancies; immuno-oncology; tumor microenvironment; immune evasion; immunotherapy; neuroinflammation; drug resistance; drug repositioning; biomarkers and therapeutic targets

(This special issue belongs to the Section Molecular Oncology)

Immune Defense Mechanisms of the External, Middle, and Inner Ear

edited by

Chul Ho Jang

submission deadline 31 Oct 2026 | Viewed by 211 | Submission Open

Keywords: ear immunology; mucosal immunity; autoimmune inner ear disease (AIED); innate immune response; blood–labyrinth barrier; middle ear immune defense

(This special issue belongs to the Section Molecular Immunology)

Nanotechnology in Precision Medicine for Pancreatic Cancer

edited by Virendar Kumar

submission deadline 31 Oct 2026 | Viewed by 207 | Submission Open

Keywords: nanotechnology; precision medicine; pancreatic cancer; pancreatic ductal adenocarcinoma (PDAC); tumor microenvironment; desmoplasia / stromal barrier; targeted drug delivery; stimuli-responsive nanocarriers; theranostics; nucleic acid therapeutics (siRNA / mRNA); cancer immunotherapy; translational nanomedicine/clinical translation

(This special issue belongs to the Section Molecular Nanoscience)

Effects of Oxidative Stress and Mitochondrial Function on Lifespan

edited by Ines Sanchez-Roman

submission deadline 31 Oct 2026 | Viewed by 206 | Submission Open

Keywords: aging; mitochondrial dysfunction; oxidative stress; genomic instability; longevity; aging-associated diseases; interventions; reactive oxygen species

(This special issue belongs to the Section Molecular Biology)

Multi-Omics and AI-Driven Discovery of Abiotic Stress Resilience in Crops

edited by

Romit Seth

submission deadline 31 Oct 2026 | Viewed by 206 | Submission Open

Keywords: genomics; pangenome; abiotic stress; multi-omics; artificial intelligence; climate extremes; predictive breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Targeted Lipidomics Approaches in Cardiometabolic Diseases: From Sample Preparation to Data Interpretation for Combined Multiomics Analysis

edited by

Camelia Sorina Stancu

and

Loredan Stefan Niculescu

submission deadline 31 Oct 2026 | Viewed by 204 | Submission Open

Keywords: biomarkers; cardiometabolic diseases; cell signaling; lipids; lipid metabolism; lipoproteins; methodology; multiomics; therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Reparative Therapeutic Strategies in Neurodegenerative Diseases

edited by

Cesar Borlongan

and Amir Hadanny

submission deadline 31 Oct 2026 | Viewed by 202 | Submission Open

Keywords: neurodegeneration; cell death signaling; oxidative stress; mitochondrial dysfunction; brain repair

(This special issue belongs to the Section Molecular Neurobiology)

Acute Lymphoblastic Leukemia (ALL): From Molecular Drivers to Therapeutic Innovation

edited by Carmen Maldonado-Bernal

submission deadline 31 Oct 2026 | Viewed by 201 | Submission Open

Keywords: acute lymphoblastic leukemia; minimal residual disease; molecular drivers; genetic drivers treatment approaches; immunotherapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Inherited Metabolic Disorders: Genetic Insights and Therapeutic Strategies

edited by

Fabiano Poswar

and Kristiane Michelin-Tirelli

submission deadline 31 Oct 2026 | Viewed by 200 | Submission Open

Keywords: inherited metabolic disorders; animal models; biomarkers; clinical laboratory techniques; tandem mass spectrometry; high-throughput nucleotide sequencing; cell- and tissue-based therapy; genetic therapy; enzyme replacement therapy; precision medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Modifications Driven by Parasite–Host Interplay

edited by

Claudia Hallal-Calleros

submission deadline 31 Oct 2026 | Viewed by 200 | Submission Open

Keywords: pathogens; molecular pathogenesis; immunomodulation; evasion; host defense mechanisms; parasitic signaling

(This special issue belongs to the Section Molecular Biology)

Bioactive Foods in Metabolic Disease: Mechanisms and Therapeutic Opportunities

edited by Salima Akter and

Bonglee Kim

submission deadline 31 Oct 2026 | Viewed by 199 | Submission Open

Keywords: metabolic diseases; medicinal foods; nutrient signaling; functional nutrition; insulin resistance; metabolomics; phytochemicals; precision nutrition; gut microbiome

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Epigenetic Regulation in Health and Disease: From Molecular Mechanisms to Clinical Applications

edited by

Sara C. Zapico

submission deadline 31 Oct 2026 | Viewed by 196 | Submission Open

Keywords: epigenetic modifications; DNA methylation; histone modifications; chromatin remodeling; non-coding RNAs; environmental epigenetics; development and aging; disease epigenetics; translational epigenetics; precision medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

Biochemical Functions and Therapeutic Potential of Dietary Bioactive Peptides

edited by

Chi-Ching Lee

submission deadline 31 Oct 2026 | Viewed by 195 | Submission Open

Keywords: bioactive peptides; molecular mechanisms; structure–activity relationship; peptidomics; functional foods; by-product valorization; antioxidant activity; bioavailability; cellular signaling; multidisciplinary approaches

(This special issue belongs to the Section Biochemistry)

Research on the Immunomodulatory Role of Macrophages

edited by

Daniel Paparini

submission deadline 31 Oct 2026 | Viewed by 194 | Submission Open

Keywords: disease models; immunometabolism; extracellular vesicles; biomarkers; inflammation; therapeutic targets; pregnancy

(This special issue belongs to the Section Molecular Immunology)

Progress in Functional Genomics and Regulation of Gene Expression

edited by Alejandro Bravo-Patino

submission deadline 31 Oct 2026 | Viewed by 194 | Submission Open

Keywords: functional genomic; gene regulation; gene interactions; biomarkers; differential gene expression; epigenetics and gene regulation

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Studies on Natural Products: Anti-Inflammatory, Immune Response, and Anti-Bacterial Activities

edited by Hicham Wahnou

submission deadline 31 Oct 2026 | Viewed by 194 | Submission Open

Keywords: natural products; anti-inflammatory; immune response; antibacterial; molecular mechanisms; phytochemicals; immunomodulation; probiotics; prebiotics; synbiotics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Computing Methods to Improve the Polymerization/Performance of Biopolymers and Their Composites

edited by

Qi Bao

submission deadline 31 Oct 2026 | Viewed by 193 | Submission Open

Keywords: biopolymers; PLA; PHA; PHB; molecular dynamic; DFT; catalyst; simulation; calculation; artificial intelligence

(This special issue belongs to the Section Materials Science)

Pharmacological Perspectives for Natural Products

edited by Ilsamar Mendes Soares

submission deadline 31 Oct 2026 | Viewed by 193 | Submission Open

Keywords: natural products; pharmacology; bioactivity; molecular targets; ethnopharmacology

(This special issue belongs to the Section Molecular Pharmacology)

Autophagy in Aging: Molecular Mechanisms and Therapeutic Implications

edited by

Nabil Eid

and

Fabian Davamani Amalraj

submission deadline 31 Oct 2026 | Viewed by 192 | Submission Open

Keywords: autophagy; aging; mitophagy; molecular mechanisms

(This special issue belongs to the Section Molecular Biology)

Recent Research Progress in Metal Complexes

edited by

Zubair Ahmed

submission deadline 31 Oct 2026 | Viewed by 191 | Submission Open

Keywords: coordination chemistry; metal–ligand complexes; ligand design and synthesis; d-block and f-block metals; spectroscopic and analytical characterizations; computational chemistry and theoretical investigations; photochemical properties and optoelectronic applications; metal complexes as catalysis; bioinorganic and medicinal applications

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Spatial Multi-Omics: From Molecular Maps to Precision Medicine

edited by

Jinxia Dai

submission deadline 31 Oct 2026 | Viewed by 190 | Submission Open

Keywords: multi-omics; spatial multi-omics; cell-type-specific molecular alterations; tissue microenvironments; molecular diagnostics; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Adrenal Endocrinology: Molecular Insights and Emerging Trends

edited by

Claudio Letizia

Luigi Petramala

and Francesco Circosta

submission deadline 31 Oct 2026 | Viewed by 187 | Submission Open

Keywords: adrenal disorders; steroid profiling; multi-omics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Congenital Heart Disease: From Molecular Mechanisms to Therapeutic Strategies

edited by

José Manuel Rodríguez-Pérez

and

Nonanzit Pérez-Hernández

submission deadline 31 Oct 2026 | Viewed by 186 | Submission Open

Keywords: genetics; gene expression; epigenetics; non-coding RNAs; omics data analysis; cardiogenesis; environmental risk factors; disease marker

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

High Fat Diet Metabolism and Diseases: 2nd Edition

edited by

Luís Fernando Barbisan

and

Miguel Walter Fornés

submission deadline 31 Oct 2026 | Viewed by 184 | Submission Open

Keywords: diet; fat; high-fat diets; obesity; NAFLD; metabolism; reproductive system; lungs; pathology

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Recent Advances in Therapeutic Targets for Musculoskeletal Tumors

edited by Japneet Kaur

submission deadline 31 Oct 2026 | Viewed by 183 | Submission Open

Keywords: musculoskeletal tumors; sarcoma; bone metastasis; tumor microenvironment; targeted therapy; immunotherapy; biomarkers; drug resistance; signaling pathways; cancer biology

(This special issue belongs to the Section Molecular Oncology)

Advances in Gene and Nucleic Acid-Based Therapeutics: From Molecular Innovations to Potential Misuse

edited by

Teruaki Tozaki

submission deadline 31 Oct 2026 | Viewed by 182 | Submission Open

Keywords: gene therapy; nucleic acid therapeutics; mRNA therapeutics; lipid nanoparticles (LNPs); genome editing (CRISPR/Cas); gene delivery systems; cell therapy; pharmacokinetics and safety; gene doping; detection methods

(This special issue belongs to the Section Molecular Genetics and Genomics)

Displaying special issue 1301-1350 on page 27 of 64.

Go to page 25 26 27 28 29

Journal Menu

Journal Browser

Special Issues

Further Information

Guidelines

MDPI Initiatives

Follow MDPI