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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Pancreatic Diseases: Molecular Pathology and Therapeutics
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 1221 | Submission Open
Keywords: pancreatic cancer; acute pancreatitis; chronic pancreatitis; diabetes; inflammation; molecular markers; therapeutic strategies; genetic predispositions; diagnostic tools
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Research on Bioactive Natural Products: 2nd Edition submission deadline 20 May 2026 | 1 articles | Viewed by 1205 | Submission Open
Keywords: chronic disorders; bioactives; natural sources; sustainable sources; biomolecular; structure– activity relationship; synergism; health promoting; bio-functional; products; supplements; nutraceuticals; drugs
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Multifunctional Magnetic Nanoparticles: Synthesis, Properties, and Biomedical Applications submission deadline 20 May 2026 | Viewed by 1196 | Submission Open
Keywords: magnetic nanoparticles; molecular functionalization; magnetocaloric materials; drug delivery systems; molecular imaging; magnetic memory; nanocomposites; nanophosphors; environmental remediation; energy storage materials; magnetic biosensing; biofunctional interfaces
(This special issue belongs to the Section Molecular Nanoscience)
Colorectal Cancers: New Approach to Their Pathology, Diagnosis and Therapy
edited by
submission deadline 20 May 2026 | 2 articles | Viewed by 1192 | Submission Open
Keywords: occult blood test; colorectal cancer; colonoscopy; rectal bleeding; abdominal pain; hemicolectomy; novel oncological drugs
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advancements in Regenerative Medicine Research
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 1191 | Submission Open
Keywords: regenerative medicine; tissue repair; wound healing; stem cells; cell differentiation; cell signalling; gene regulation; mechanotransduction; precision medicine
(This special issue belongs to the Section Molecular Biology)
Advanced Molecular Research on Pregnancy Complication Mechanisms submission deadline 20 May 2026 | 1 articles | Viewed by 1129 | Submission Open
Keywords: hypertensive pregnancy disorders; gestational diabetes; intrauterine growth restriction; maternal metabolism in pregnancy complications; genetic and epigenetic mechanisms in pregnancy complications; immunology in pregnancy complications
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Gastrointestinal Inflammation: From Pathogenesis to Molecular Diagnosis and Treatment
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 1062 | Submission Open
Keywords: gastrointestinal tract; inflammation; gastroenteritis; infection; microbiome; mucosal epithelium; immune cells; enteric nervous system
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Electrochemical Nanomaterials for Energy and Catalysis
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 1038 | Submission Open
Keywords: advanced micro- and nanomaterials for electrochemical applications; electrochemical energy storage; electrocatalysis; photoelectrochemical water splitting; electrochemical sensors; supercapacitor; batteries; nanocomposites and functionalized materials; energy storage and conversion application; natural resources-based materials
(This special issue belongs to the Section Molecular Nanoscience)
Analysis on Effector and Regulatory Molecules in Renal Diseases
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 1033 | Submission Open
Keywords: effector molecules; regulatory molecules; membrane attack complex (MAC); perforin; granzyme; immune complex; neutrophil extracellular traps (NETs); proteolytic enzymes; reactive oxygen species; infection-related glomerulonephritis (IRGN); nephritis-associated plasmin receptor (NAPlr); streptococcal pyrogenic exotoxin B (SPEB); adhesion molecules
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Exploring Rare Diseases: Genetic, Genomic and Metabolomic Advances: 2nd Edition
edited by and
submission deadline 20 May 2026 | 1 articles | Viewed by 992 | Submission Open
Keywords: rare diseases; genotype– phenotype analyses; NGS; mass spectrometry; biomarker discovery; molecular targeted therapy
(This special issue belongs to the Section Molecular Genetics and Genomics)
Natural and Synthetic Modified Nucleic Acids: Their Properties, Functions and Applications
edited by
submission deadline 20 May 2026 | 2 articles | Viewed by 989 | Submission Open
Keywords: DNA; RNA; nucleic acid analogues; modified nucleosides; modified nucleosides identification techniques; nucleoside modifying enzymes; gene therapy; therapeutic nucleic acids; biomedical applications; drug delivery
(This special issue belongs to the Section Molecular Biology)
Recent Advances in the Structure, Biological Activity and Structure–Activity Relationship of Polysaccharides submission deadline 20 May 2026 | 2 articles | Viewed by 942 | Submission Open
Keywords: natural polysaccharides; phytochemicals; nutraceuticals; structure– activity relationship; anticancer potential; immunomodulation
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Eukaryotic DNA Replication—from Bench to Bedside
edited by Heinz-Peter Nasheuer
submission deadline 20 May 2026 | 1 articles | Viewed by 919 | Submission Open
Keywords: genome stability; cell cycle; DNA replication; chromatin replication; replication origins— selection; licensing and firing; replication forks— smoothly progressing and under stress; role of DNA replication in cancer and other human diseases; disease treatment opportunities
(This special issue belongs to the Section Molecular Genetics and Genomics)
Surfactants: Design, Synthesis and Application
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 885 | Submission Open
Keywords: surfactants; adsorption phenomena; critical micellar concentration (CMC); hydrophilic– lipophilic balance (HLB); critical packing parameter (CPP); emulsion formulations; vesicular and non-vesicular origin nanocarriers; drug delivery; theranostics
(This special issue belongs to the Section Materials Science)
The Role of Extracellular Vesicles in Disease and Therapeutic Applications
edited by Sunyoung Park
submission deadline 20 May 2026 | 1 articles | Viewed by 825 | Submission Open
Keywords: extracellular vesicles (EVs); disease biomarkers; EV-based therapeutics; cancer diagnosis; drug delivery; immune modulation; regenerative medicine
(This special issue belongs to the Section Molecular Biology)
Advances in the Translational Preclinical Research
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 812 | Submission Open
Keywords: translational preclinical research; drug discovery; cancer therapies; in vitro and in vivo experiments; biological mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Synthesis and Application of Natural and Inspired-Natural Products
edited by Mauro de Nisco
submission deadline 20 May 2026 | 1 articles | Viewed by 785 | Submission Open
Keywords: natural products; natural substances; derivative; synthesis; application
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Emerging Roles of the Gut-Brain Axis (GBA) in Health and Disease
edited by Vinata Vedam-Mai
submission deadline 20 May 2026 | 1 articles | Viewed by 760 | Submission Open
Keywords: gut– brain axis; gut microbiota; brain function; diagnostic tools
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Unraveling the Molecular Landscape of Primary Brain Tumors
edited by , Francesco Pasqualetti and Tamara Ius
submission deadline 20 May 2026 | Viewed by 741 | Submission Open
Keywords: primary brain tumors; molecular oncology; glioma; glioblastoma; biomarkers; targeted therapy; epigenetics; tumor microenvironment; genomic profiling; translational research
(This special issue belongs to the Section Molecular Neurobiology)
Survival of the Fittest: Physiological Adaptations of Insects in Hostile Environments submission deadline 20 May 2026 | Viewed by 672 | Submission Open
Keywords: insect adaptation; temperature tolerance; insect physiology; detoxification; symbiosis and stress tolerance mechanisms
(This special issue belongs to the Section Molecular Biology)
New Molecular Insights into Antibacterial Material
edited by Rahela Carpa
submission deadline 20 May 2026 | 1 articles | Viewed by 627 | Submission Open
Keywords: antimicrobial resistance; nanoparticles; biopolymers; antimicrobial peptides; antimicrobial materials
(This special issue belongs to the Section Materials Science)
Computational Approaches in Biomedicine: Innovations and Insights
edited by
submission deadline 20 May 2026 | Viewed by 599 | Submission Open
Keywords: computational biomedicine; artificial intelligence; machine learning; omic technologies; system biology; medical imaging; structural biology; drug discovery
(This special issue belongs to the Section Molecular Informatics)
Lipoproteins—Opportunities for the Development of Nanotherapeutics in Chronic Disease
edited by
submission deadline 20 May 2026 | Viewed by 597 | Submission Open
Keywords: lipoproteins; LDL; HDL; nanotherapeutics; chronic disease; targeted therapy; drug delivery
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Repair Mechanisms of Stem Cells submission deadline 20 May 2026 | Viewed by 594 | Submission Open
Keywords: stem cell biology; stem cells; stem cell therapy; tissue regeneration
(This special issue belongs to the Section Biochemistry)
Chessboard: How Plants and Insects Outsmart Each Other
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 589 | Submission Open
Keywords: acarology; biotic stress; entomology nitric oxide; oxidative stress; phytopathology; reactive nitrogen species; reactive oxygen species
(This special issue belongs to the Section Molecular Plant Sciences)
Current Advance in Infectious and Inflammatory Diseases submission deadline 20 May 2026 | 1 articles | Viewed by 576 | Submission Open
Keywords: inflammatory diseases; infectious diseases; host– pathogen interactions; antimicrobial resistance; immune modulation; cytokine signaling
(This special issue belongs to the Section Molecular Microbiology)
The Role of Transcription Factors in Antioxidant Pathways
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 555 | Submission Open
Keywords: transcription factor; oxidative stress; NRF1/2; NRF3; NFkB; P53; antioxidant-response elements; neurologial diseases; metabolic diseases; cancer
(This special issue belongs to the Section Molecular Biology)
Current Research in Membrane Transporters, Channels, and Receptors
edited by Ivana Vrhovac Madunic
submission deadline 20 May 2026 | 1 articles | Viewed by 547 | Submission Open
Keywords: membrane transporters; cell membrane; transmembrane proteins; glucose transport; ion channels; cellular receptors; signal tranduction; pathophysiology; diabetes; aging
(This special issue belongs to the Section Molecular Biology)
New Biomarkers in Pancreatic Diseases
edited by and
submission deadline 20 May 2026 | Viewed by 529 | Submission Open
Keywords: pancreatic disease; pancreatic cancer; pancreatitis; biomarker; RNA
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cell Death in Human Diseases: Mechanisms, Biomarkers and Therapeutic Opportunities
edited by
submission deadline 20 May 2026 | Viewed by 512 | Submission Open
Keywords: cell death; apoptosis; necroptosis; ferroptosis; pyroptosis; human disease; biomarkers
(This special issue belongs to the Section Molecular Biology)
X-Linked Disorders: Epigenetic and Environmental Modulation of Phenotypes
edited by Yoram Chaiter and
submission deadline 20 May 2026 | Viewed by 505 | Submission Open
Keywords: X-linked disorders; epigenetics; environmental factors; gene expression; clinical manifestations
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Research in Ocular Inflammation and Infection
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 469 | Submission Open
Keywords: ocular infections; uveitis; choroiditis; masquerade syndrome; pseudo-uveitis; intraocular lymphoma; retinal dystrophy; ocular inflammation; neuroinflammation; immunotherapy-induced uveitis; autoimmune eye diseases; sarcoidosis; OCT; indocyanine green angiography
(This special issue belongs to the Section Molecular Immunology)
Molecular Mechanisms of Skeletal Muscle Adaptation
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 453 | Submission Open
Keywords: skeletal muscle; adaptive responses; muscle physiology; genomics; transcriptomics; proteomics; molecular mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Endoplasmic Reticulum Stress and Apoptosis—Second Edition submission deadline 20 May 2026 | 1 articles | Viewed by 430 | Submission Open
Keywords: ER stress; apoptosis initiated by ER stress; cellular survival; redox homeostasis of ER; autophagy initiated by ER stress; cell death pathways initiated by ER stress
(This special issue belongs to the Section Biochemistry)
Advances in Biological Breeding and Molecular Biology of Tropical Crops
edited by Yongzan Wei
submission deadline 20 May 2026 | 1 articles | Viewed by 429 | Submission Open
Keywords: tropical crops; biological breeding; tropical fruit; molecular biology; gene editing; transcrip-tional regulation; genomics
(This special issue belongs to the Section Molecular Plant Sciences)
Interfaces for the Impact of Magnetic Pulses or EMF in Molecular Biology
edited by Richard H. W. Funk
submission deadline 20 May 2026 | Viewed by 428 | Submission Open
Keywords: electromagnetic treatment; magnetic pulses; biological interface; cell biology; molecular biology; signaling cascades; clinical treatment; monitoring; sensors
(This special issue belongs to the Section Molecular Biophysics)
Heart Failure: From Pathogenesis to Innovative Treatments
edited by Volker Adams and
submission deadline 20 May 2026 | 1 articles | Viewed by 397 | Submission Open
Keywords: heart failure; HFrEF; HFpEF; comorbidities; pathophysiology; treatment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Pathogenesis and Treatment of Prostate Cancer submission deadline 20 May 2026 | Viewed by 367 | Submission Open
Keywords: prostate cancer; pathogenesis; genetic mutations; target therapy; surgery; radiation therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Understanding Respiratory Virus–Host Interactions
edited by Kun Li
submission deadline 20 May 2026 | Viewed by 348 | Submission Open
Keywords: respiratory viruses; virus– host interactions; molecular mechanisms; viral replication; host– immune response; molecular pathogenesis; molecular signaling; antiviral strategies
(This special issue belongs to the Section Molecular Microbiology)
Recent Advances in Neurofibromatosis Type 1: From Molecular Insights to Novel Therapies
edited by László Szabó and
submission deadline 20 May 2026 | Viewed by 341 | Submission Open
Keywords: neurofibromatosis type 1; genotype– phenotype analyses; molecular pathogenesis; next-generation sequencing (NGS); molecular targeted therapy; MEK inhibitors; imaging studies
(This special issue belongs to the Section Molecular Neurobiology)
Advanced Research in Nanophotonics and Biophotonics
edited by
submission deadline 20 May 2026 | Viewed by 337 | Submission Open
Keywords: biophotonics; spectroscopy; light scattering; Raman/FTIR; cancer; Alzheimer's and Parkinson’ s diseases; nanophotonics; plasmonics; nano-biophotonics
(This special issue belongs to the Section Molecular Nanoscience)
Molecular Insights into Antimicrobial Agents: Mechanisms and Applications submission deadline 20 May 2026 | Viewed by 315 | Submission Open
Keywords: antimicrobial compounds; antibacterial activity; antibiotic resistance; pathogen-tailored therapeutic targeting; novel antimicrobials; molecular aspects of the mechanisms of action of antibacterial substances; effectiveness of antibacterial substances
(This special issue belongs to the Section Biochemistry)
New Advances in Reproductive Immunology and Pathology
edited by Silvia Giugliano
submission deadline 20 May 2026 | Viewed by 314 | Submission Open
Keywords: maternal– fetal immune tolerance; reproductive immunopathology; cytokine signaling in pregnancy; immune-related infertility; metabolome-immune crosstalk; microbiome influence on fertility
(This special issue belongs to the Section Molecular Immunology)
Advanced Research on Comparative Reproductive Physiology submission deadline 20 May 2026 | Viewed by 305 | Submission Open
Keywords: andrology; sperm; oocyte; gamete interactions; reproductive morphology; reproductive endocrinology; omics; epigenetics; pregnancy; all animal species
(This special issue belongs to the Section Molecular Biology)
Unraveling Neuroimmune Disorders: From Pathogenic Pathways to Biomarker-Driven Precision Medicine
edited by
submission deadline 20 May 2026 | Viewed by 280 | Submission Open
Keywords: innate immunity; adaptive immunity; inflammation; autoantibodies; peptides; cytokines; receptors; leukocytes; extracellular vesicles; signal transduction; apoptosis
(This special issue belongs to the Section Molecular Immunology)
Molecular Advances in Primary Colorectal Cancer and Liver Metastases
edited by Alexandros E. Giakoustidis
submission deadline 20 May 2026 | Viewed by 278 | Submission Open
Keywords: colorectal cancer; metastasis; treatment; management; screening; genetic alterations; epigenetic alterations; genomics; epigenomics; methylation; liver-directed therapy; radiation; immunotherapy; peritoneal carcinomatosis; monotherapy; chemotherapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms Linked to Exercise
edited by Igor Zubrzycki
submission deadline 20 May 2026 | Viewed by 264 | Submission Open
Keywords: molecular mechanisms; exercise adaptations; translational health
(This special issue belongs to the Section Molecular Biology)
Targeted Protein Degradation: From Molecular Mechanisms to Therapeutic Applications
edited by
submission deadline 20 May 2026 | Viewed by 263 | Submission Open
Keywords: targeted protein degradation; ubiquitin– proteasome system; PROTAC; drug design; medicinal chemistry
(This special issue belongs to the Section Molecular Pharmacology)
Latest Molecular Advances in Prostate Cancer
edited by Rejane Maira Góes
submission deadline 20 May 2026 | Viewed by 251 | Submission Open
Keywords: prostate cancer; androgen signaling; metabolic reprogramming; tumor microenvironment; inflammation; immunotherapy; chemoprotection; phytotherapy
(This special issue belongs to the Section Molecular Oncology)
Molecular Application of Hyaluronan in Tissue Healing submission deadline 20 May 2026 | Viewed by 243 | Submission Open
Keywords: wound healing; inflammation; remodeling; chronic wound; wound dressing; scar tissue; sound tissue; biomarkers; chemical modification; crosslinked; biopolymer; biological activity
(This special issue belongs to the Section Macromolecules)
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