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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Quantum Chemical Intelligence: New Horizons of Molecular Structure and Reactivity

edited by

Mihai V. Putz

submission deadline 30 Nov 2026 | Viewed by 527 | Submission Open

Keywords: chemical bond and bonding; quantum states and measurements; chemical reactivity; valence models; complex coordination; reaction coordinates and paths; bio-nano-materials

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Hormetic Responses of Plants to Environmental Stress

edited by

Michael Moustakas

submission deadline 30 Nov 2026 | Viewed by 525 | Submission Open

Keywords: hormesis; environmental stress; dose–response; molecular mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

Cancer Biomarkers: From Early Detection to Prognosis

edited by

Luís Lima

submission deadline 30 Nov 2026 | 1 articles | Viewed by 515 | Submission Open

Keywords: cancer biomarkers; early detection; prognosis; liquid biopsy; personalized oncology; multi-omics; translational research; predictive modeling

(This special issue belongs to the Section Molecular Oncology)

Research Advances in Vegetable Breeding and Genetics

edited by

Jinglei Wang

submission deadline 30 Nov 2026 | 1 articles | Viewed by 512 | Submission Open

Keywords: vegetable; breeding; genetics; genomics; gene editing; marker-assisted selection; stress resistance; quality improvement; crop improvement; horticulture

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Nutrient Uptake and Utilization in Plants

edited by

Stella Karydogianni

submission deadline 30 Nov 2026 | Viewed by 502 | Submission Open

Keywords: agriculture and crop improvement; molecular and cellular mechanisms; nitrogen; nutrient efficiency; protein

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Research on Skin Inflammation (2nd Edition)

edited by

Nabiha Yusuf

submission deadline 30 Nov 2026 | 1 articles | Viewed by 499 | Submission Open

Keywords: skin inflammation; molecular diagnosis; dermatitis; molecular pathogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bridging the Omics of Protein Landscape of Aging and Disease: New Insights and Opportunities

edited by

Fátima Milhano Santos

submission deadline 30 Nov 2026 | Viewed by 498 | Submission Open

Keywords: age-related disease; aging; biomarkers; chronic diseases; neurodegenerative diseases; ocular diseases; proteomics; kidney diseases

(This special issue belongs to the Section Molecular Biology)

Advances in Plant-Derived Nanomaterials: From Molecular Mechanisms to Biofortification

edited by

Ágnes Szepesi

submission deadline 30 Nov 2026 | Viewed by 494 | Submission Open

Keywords: nanotechnology; green synthesis; sustainable nanomaterials; nano–bio interactions; crop production; plant-based solutions; bio-corona

(This special issue belongs to the Section Molecular Plant Sciences)

Nutrition of Crustaceans: A Molecular Perspective

edited by

Cheng Chi

submission deadline 30 Nov 2026 | Viewed by 493 | Submission Open

Keywords: crustacean nutrition; molecular mechanisms; aquaculture; nutrient metabolism; reproduction

(This special issue belongs to the Section Molecular Biology)

Molecular Insights into Probiotics and Prebiotics in Gut Health and Disease

edited by

Hikmate Abriouel

submission deadline 30 Nov 2026 | Viewed by 487 | Submission Open

Keywords: probiotics; prebiotics; gut microbiota; intestinal health; dysbiosis; host–microbe interactions; omics; gut–brain axis

(This special issue belongs to the Section Molecular Microbiology)

Peptides in Healthcare and Beyond: Emerging Roles in Skincare, Nutrition, Medicine, and Animal Health

edited by

Jiazhong Li

and Lijing Fang

submission deadline 30 Nov 2026 | Viewed by 484 | Submission Open

Keywords: peptides; efficacy; healthcare; skincare; nutrition; medicine; animal health

(This special issue belongs to the Section Biochemistry)

Bioactive Peptides from Natural Sources: Pharmacological Effects, Recombinant Expression, Modification, Molecular Mechanisms, and Therapeutic Potential

edited by Linchun Shi

submission deadline 30 Nov 2026 | Viewed by 482 | Submission Open

Keywords: bioactive peptides; functional peptides; antimicrobial peptides; host-defense peptides; venom peptides; ribosomally synthesized and post-translationally modified peptides; peptide precursor gene families; comparative genomics; phylogeny; structure–activity relationship

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Mitochondrial DNA and Its Multiple Functions in Health and Disease

edited by

Izinara Rosse

and Vanessa F. Gonçalves

submission deadline 30 Nov 2026 | Viewed by 482 | Submission Open

Keywords: mitochondrial DNA; mtDNA; mitochondrial genome sequencing; mitochondrial dysfunction; precision medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

The Influence of Genetics on Lymphatic System Diseases

edited by

Tomomi Watanabe-Asaka

submission deadline 30 Nov 2026 | Viewed by 472 | Submission Open

Keywords: lymphatic system; gene expression; disease model; medical application; lymphatic development; lymphatic function

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Pathogenesis and Targeted Therapies of Hematological Malignancies

edited by

Can Küçük

submission deadline 30 Nov 2026 | 1 articles | Viewed by 469 | Submission Open

Keywords: hematological malignancies; precision oncology; molecular mechanisms; therapeutic resistance; targeted therapy; cellular immunotherapies; multi-omics; artificial intelligence; translational medicine

(This special issue belongs to the Section Molecular Oncology)

Molecular, Cellular and Systems Research on Neuroanatomy, Brain Function and Its Impact on Human Behavior

edited by

Frank Schmitz

submission deadline 30 Nov 2026 | Viewed by 464 | Submission Open

Keywords: central nervous system; neuroanatomy; human behavior; nuclei; neuronal circuits; connectivity channels

(This special issue belongs to the Section Molecular Neurobiology)

Molecular and Cellular Pathways Involved in Age-Related Musculoskeletal Disorders

edited by

Abhishek Chandra

and Neha Dole

submission deadline 30 Nov 2026 | Viewed by 463 | Submission Open

Keywords: musculoskeletal disorders; cellular senescence; aging; genetic mutations; oxidative stress; mitochondrial dysfunction; bone homeostasis

(This special issue belongs to the Section Molecular Biology)

Effects of the Environmental Conditions on Bacterial Growth and Functions

edited by

Fernanda Abreu

submission deadline 30 Nov 2026 | Viewed by 462 | Submission Open

Keywords: bacterial growth; growth conditions; gene expression; bioproducts; biofilm; resistance; population dynamics

(This special issue belongs to the Section Molecular Microbiology)

Molecular Research on Central Nervous System Inflammatory Demyelinating Diseases

edited by Yong Guo

submission deadline 30 Nov 2026 | Viewed by 462 | Submission Open

Keywords: central nervous system; autoimmune; demyelination; inflammation; multiple sclerosis; pathology

(This special issue belongs to the Section Molecular Neurobiology)

T Cell Malignancies: Translating Basic Research into Better Therapy

edited by

Grzegorz Przybylski

submission deadline 30 Nov 2026 | Viewed by 459 | Submission Open

Keywords: T-Cell malignancies; specific target antigens; gene-targeted therapies

(This special issue belongs to the Section Molecular Oncology)

Molecular Engineering of Antimicrobial Agents: From Structure-Function Insights to Combinatorial Therapies

edited by Mingrui Liao

submission deadline 30 Nov 2026 | Viewed by 455 | Submission Open

Keywords: antimicrobial amphiphiles; antimicrobial resistance; structure–activity relationship; synergistic antimicrobial therapy; drug delivery systems

(This special issue belongs to the Section Molecular Biology)

Understanding and Combating Antimicrobial Resistance: Molecular Insights and Innovative Approaches

edited by

Giovanni Di Bonaventura

submission deadline 30 Nov 2026 | Viewed by 444 | Submission Open

Keywords: genetic mutations; horizontal gene transfer; efflux pump mechanisms; biofilm formation; novel antibiotic development; antimicrobial peptides; phage therapy; CRISPR-based tools; antimicrobial stewardship programs

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in Periodontitis

edited by Maja Miletić and

Natasa Nikolic-Jakoba

submission deadline 30 Nov 2026 | 1 articles | Viewed by 442 | Submission Open

Keywords: periodontitis; molecular mechanisms; inflammation; oral microbiome; multi-omics; biomarkers; cytokines; oxidative stress; immune regulation; tissue regeneration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances of Layered Double Hydroxides (LDH) for Corrosion Protection

edited by

Henryk Kania

submission deadline 30 Nov 2026 | Viewed by 435 | Submission Open

Keywords: layered double hydroxide (LDHs); corrosion resistance; coatings; corrosion products

(This special issue belongs to the Section Materials Science)

Molecular Progress in Male Reproduction

edited by

Ahmet Ayaz

submission deadline 30 Nov 2026 | Viewed by 435 | Submission Open

Keywords: male infertility; spermatogenesis; epigenetics; sperm function; testicular molecular biology; bioinformatics; reproductive genomics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Research in Leukemia

edited by

Juan Manuel Mejia-Arangure

submission deadline 30 Nov 2026 | Viewed by 427 | Submission Open

Keywords: leukemia; molecular biology; genetic testing; epigenomics; targeted therapy; precision medicine; diagnostic techniques; molecular pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research on Stress Signaling in Embryonic Development

edited by

Poongodi Geetha-Loganathan

and Norihisa Higashihori

submission deadline 30 Nov 2026 | Viewed by 427 | Submission Open

Keywords: stress signaling; embryonic development; morphogenesis; signal transduction; teratogenesis

(This special issue belongs to the Section Molecular Biology)

Research of Aldo-Keto Reductases in Human Disease

edited by

Ping Zhu

and

Hao Luo

submission deadline 30 Nov 2026 | 1 articles | Viewed by 425 | Submission Open

Keywords: aldo-keto reductase (AKR); protein engineering; AKR1B10; cancer biomarker; chemoresistance

(This special issue belongs to the Section Biochemistry)

The Role of Transcription Factors in Cancer

edited by

Tomasz Wilanowski

submission deadline 30 Nov 2026 | Viewed by 425 | Submission Open

Keywords: transcription factor; oncogene; tumor suppressor; nuclear receptor; genetic regulation; post-translational regulation; biomarker; drug target

(This special issue belongs to the Section Molecular Oncology)

Antimicrobial Agents and the Quest for Resistance Breakthroughs

edited by

Inês Bártolo

submission deadline 30 Nov 2026 | Viewed by 419 | Submission Open

Keywords: drug resistance; antimicrobial resistance (AMR); drug-resistant bacteria; drug-resistant viruses; drug-resistant fungi; drug-resistant parasite; drug resistance biomolecular studies; mechanism of resistance; novel antimicrobial agents; treatment of infectious diseases

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Application of Biomaterial in Skin Diseases

edited by

Danuta Nowicka

submission deadline 30 Nov 2026 | Viewed by 416 | Submission Open

Keywords: chronic dermatoses; autologus material; PRP; stem cells; growth factors

(This special issue belongs to the Section Materials Science)

Plant–Microbe Interactions Driving Abiotic Stress Adaptation

edited by Saeed Ur Rahman and Nan Hui

submission deadline 30 Nov 2026 | Viewed by 414 | Submission Open

Keywords: plant–microbe interactions; abiotic stress; rhizosphere microbiome; stress tolerance; horticultural crops; molecular mechanisms; plant growth-promoting microbes; omics approaches; sustainable agriculture; signaling pathways

(This special issue belongs to the Section Molecular Plant Sciences)

Vascular Calcification: Molecular Regulation, Inflammation and Translational Perspectives

edited by

Laia Cañes

submission deadline 30 Nov 2026 | Viewed by 413 | Submission Open

Keywords: vascular calcification; inflammation; calcium-phosphate alterations; osteogenic differentiation; vascular smooth muscle cells; cardiovascular disease

(This special issue belongs to the Section Molecular Biology)

Recent Genetic Insights into Neurodevelopmental Disorders

edited by Maria Cristina Aspromonte and Emanuela Dazzo

submission deadline 30 Nov 2026 | Viewed by 407 | Submission Open

Keywords: neurodevelopmental disorders; autism spectrum disorder; intellectual disability; attention deficit hyperactivity disorder; epilepsy; motor disorders; chromosomal rearrangements; genetic variant; integrative omics approaches

(This special issue belongs to the Section Molecular Neurobiology)

The Role of Dopamine Neurotransmission in Schizophrenia

edited by

Mirian Akemi Furuie Hayashi

submission deadline 30 Nov 2026 | Viewed by 407 | Submission Open

Keywords: schizophrenia; dopamine; dopaminergic system; neurotransmission; psychosis; pathophysiology; molecular psychiatry

(This special issue belongs to the Section Molecular Neurobiology)

Advances in the Molecular Biology of Lipids and Mitochondria

edited by

Alejandra Espinosa

submission deadline 30 Nov 2026 | Viewed by 403 | Submission Open

Keywords: lipids; lipid transport mechanisms; lipid peroxidation; mitochondrial integrity; bioenergetics; mitochondrial phospholipid

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Mechanisms in Mucosal Immunity

edited by

Mónica Vermeulen

submission deadline 30 Nov 2026 | Viewed by 398 | Submission Open

Keywords: mucosal immunity; metabolism; innate memory; trainers and inflammatory stimuli

(This special issue belongs to the Section Molecular Immunology)

Integrative Regenerative Medicine: Bridging Molecular Mechanisms and Therapeutic Applications

edited by

Jerran Santos

submission deadline 30 Nov 2026 | Viewed by 397 | Submission Open

Keywords: regenerative medicine; stem cells; molecular mechanisms; tissue engineering; organoids; biomaterials; biofabrication; clinical translation; cell therapy; integrative biology

(This special issue belongs to the Section Molecular Biology)

Advances in Research on Neurotransmitters (Second Edition)

edited by

Mario Manto

Hiroshi Mitoma

and Jing-Ning Zhu

submission deadline 30 Nov 2026 | 1 articles | Viewed by 397 | Submission Open

Keywords: neurotransmitters; GABA; glutamate; monoamines; dopamine; serotonin; norepinephrine; neuropeptides; nitric oxide; neurosteroids; stress; neurotrophins; epigenetics; gut–brain axis

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Osteogenesis: 2nd Edition

edited by

Andrea Del Fattore

submission deadline 30 Nov 2026 | Viewed by 392 | Submission Open

Keywords: osteogenesis; osteoblast; bone formation; disease; bone

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Magnetic Nanoparticles: From Synthesis and Modification to Biomedical Applications

edited by

Ahmet Kertmen

submission deadline 30 Nov 2026 | Viewed by 386 | Submission Open

Keywords: magnetite nanoparticles; colloidal interactions; X-ray characterizations; biomedical applications; method development; imaging

(This special issue belongs to the Section Molecular Nanoscience)

Apoptosis in Health and Disease: Recent Advances and Future Directions

edited by Shabnam Malik

submission deadline 30 Nov 2026 | Viewed by 382 | Submission Open

Keywords: apoptosis; programmed cell death; health and disease; cellular homeostasis; cancer; neurodegenerative disorders

(This special issue belongs to the Section Molecular Biology)

Oxidative Stress, Biomarkers and Dysregulated Lipid Metabolism in Cardiovascular Diseases

edited by

Amilia Aminuddin

and Adila Abdul A. Hamid

submission deadline 30 Nov 2026 | 1 articles | Viewed by 377 | Submission Open

Keywords: cardiovascular diseases; oxidative stress; lipid metabolism; atherosclerosis; endothelial dysfunction; inflammation; biomarkers; reactive oxygen species (ROS); dyslipidemia; vascular function

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Therapeutic Strategies for Surgical Tissue Damage, Repair and Regeneration

edited by

Alex K. Wong

submission deadline 30 Nov 2026 | Viewed by 377 | Submission Open

Keywords: surgical injury; tissue regeneration; vasculogenesis; wound healing in compromised settings; molecular therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Plant–Microbe Interactions in Alleviation of Abiotic Stress in Plants

edited by

Marzena Sujkowska-Rybkowska

submission deadline 30 Nov 2026 | Viewed by 376 | Submission Open

Keywords: abiotic stresses; plant–microbe interactions; symbiotic microbes; stress adaptation; stress-responsive genes; physio-logical responses

(This special issue belongs to the Section Molecular Plant Sciences)

Antiviral Drug Target Discovery and Design

edited by

Dongwei Kang

and Huajun Zhao

submission deadline 30 Nov 2026 | Viewed by 373 | Submission Open

Keywords: antiviral; drug discovery; drug resistance; immune and pharmacological mechanisms; immunotherapy; immunopathology; vaccines and adjuvants

(This special issue belongs to the Section Molecular Pharmacology)

New Insight into Pathogen Stress Effects on Plant Structure and Metabolism

edited by

Edmund Kozieł

and

Katarzyna Otulak-Kozieł

submission deadline 30 Nov 2026 | Viewed by 369 | Submission Open

Keywords: plant–pathogen interaction; innate immunity; ultrastructure; plant defense systems; plant physiology; signal transduction; resistance genes

(This special issue belongs to the Section Molecular Plant Sciences)

Roles and Mechanisms of Non-Coding RNAs in Human Health and Disease: 2nd Edition

edited by

Marco Ragusa

and

Cristina Barbagallo

submission deadline 30 Nov 2026 | Viewed by 368 | Submission Open

Keywords: non-coding RNAs; microRNAs; long non-coding RNAs; circular RNAs; biomarkers; polymorphisms; cancer; degenerative diseases; therapy

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Insight into Polymer Dynamics

edited by

Sirui Ge

submission deadline 30 Nov 2026 | Viewed by 367 | Submission Open

Keywords: polymer dynamics; glass transition; segmental relaxation; bulk relaxation; structure–property relationship; functional polymers; spectroscopy; instrumental characterization; simulations and modeling; polymer diffusion

(This special issue belongs to the Section Materials Science)

RNA Structure, Folding and Cellular Function: Mechanisms and Biological Significance

edited by

Ilias Skeparnias

submission deadline 30 Nov 2026 | Viewed by 350 | Submission Open

Keywords: RNA structure; RNA folding; RNA–protein interactions; R-loops; RNA:DNA hybrids; non-coding RNA; RNA biogenesis; gene regulation; ribozymes; RNA therapeutics

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 1401-1450 on page 29 of 62.

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