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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Anticancer Drugs: Current Status and Future Directions submission deadline 20 Jun 2026 | Viewed by 113 | Submission Open
Keywords: anticancer drugs; hybrids; combinations; nanoparticles
(This special issue belongs to the Section Molecular Pharmacology)
Structure and Function of Subcellular Organelle and Protein-Membrane Systems
edited by
submission deadline 20 Jun 2026 | Viewed by 112 | Submission Open
Keywords: immuno-electron microscopy; cell signaling; comparative anatomy; diagnosis; molecular recognition; molecular complexes; electro-chemistry; liquid-phase synthesis; metal sedimentation; membrane endoskeleton
(This special issue belongs to the Section Molecular Biophysics)
Molecular and Adaptive Mechanisms in Plant Genetics
edited by
submission deadline 20 Jun 2026 | Viewed by 108 | Submission Open
Keywords: forest genetics; breeding techniques; molecular breeding
(This special issue belongs to the Section Molecular Plant Sciences)
Deciphering the Molecular Mechanisms That Regulate Plant Disease and Immunity
edited by Bourlaye Fofana and
submission deadline 20 Jun 2026 | Viewed by 104 | Submission Open
Keywords: plants; biotic stressors; molecular mechanisms; omics technologies; plant immunity
(This special issue belongs to the Section Molecular Plant Sciences)
Medicinal Plants, Animal-Derived Products, and Natural Compounds: Roles in Health and Disease submission deadline 20 Jun 2026 | Viewed by 51 | Submission Open
Keywords: natural bioactive compounds; medicinal plants; animal-derived products; marine natural products; chronic diseases; inflammation; oxidative stress; molecular mechanisms; therapeutic peptides; natural toxins; antioxidant activity; anti-inflammatory agents; nanoformulations; nanodelivery systems; drug delivery; pharmacological properties; translational research; integrative medicine; natural therapeutics; disease prevention
(This special issue belongs to the Section Bioactives and Nutraceuticals)
The Evolution, Genetics and Pathogenesis of Viruses, 2nd Edition
edited by
submission deadline 20 Jun 2026 | Viewed by 37 | Submission Open
Keywords: viruses; genome structure; viral RNA/DNA; replication viral cycle; recombination; viral infection; antiviral agents
(This special issue belongs to the Section Molecular Microbiology)
New Molecular Mechanisms and Markers in Inflammatory Disorders, 4th Edition
edited by
submission deadline 20 Jun 2026 | Viewed by 33 | Submission Open
Keywords: inflammation; inflammatory disorders; biomarkers; molecular mechanism of inflammation; molecular signaling
(This special issue belongs to the Section Molecular Immunology)
Natural Products: Pharmacological Insights and Advances
edited by
submission deadline 20 Jun 2026 | Viewed by 12 | Submission Open
Keywords: natural products; biological activity; pharmacology; mechanism of action; molecular targets
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Mechanisms and Therapies of Pancreatic Cancer: 3rd Edition submission deadline 20 Jun 2026 | Submission Open
Keywords: pancreatic cancer; metabolism; cellular plasticity; tumor microenvironment; target therapy
(This special issue belongs to the Section Molecular Oncology)
Molecular Genetic Mechanism of Stress Resistance in Plants
edited by Mohammad Nurul Matin
submission deadline 21 Jun 2026 | Viewed by 8 | Submission Open
Keywords: stress response and resistance; environmental adaptation; abiotic and biotic stress; gene regulation network; functional genomics; molecular signalling pathways; CRISPR/cas systems; epigenetic regulation; transcriptome profiling; metabolic reprogramming; stress-responsive genes
(This special issue belongs to the Section Molecular Genetics and Genomics)
Functions and Applications of Natural Products: 2nd Edition
edited by
submission deadline 25 Jun 2026 | 1 articles | Viewed by 671 | Submission Open
Keywords: natural products; biomedicine/phytomedicine; biologically active extracts and compounds; pharmacological and toxicological mechanisms of action
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Research in Pregnancy-Related Complications
edited by Kallirhoe Kalinderi
submission deadline 25 Jun 2026 | Viewed by 244 | Submission Open
Keywords: preeclampsia; gestetional diabetes mellitus; pregnancy; complications; gene; molecular; pathways; biomarkers; diagnosis; therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Colorectal Cancer: A Molecular Genetics Perspective (2nd Edition)
edited by
submission deadline 25 Jun 2026 | Viewed by 105 | Submission Open
Keywords: colorectal cancer; chromosomal and microsatellite instability; CpG island methylator phenotype; molecular characteristics; early diagnosis; targeted therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Mitochondrial Function in Human Health and Disease: 3rd Edition
edited by
submission deadline 25 Jun 2026 | Viewed by 85 | Submission Open
Keywords: mitochondial genesis and disease; mitochondrial function and aging; mitochondrial dysfunction and cancer; mitochondrial function and apoptosis; mitophage; autophage; mitochondrial AKT
(This special issue belongs to the Section Biochemistry)
Molecular Progression of Gut Microbiota—2nd Edition
edited by
submission deadline 25 Jun 2026 | Viewed by 80 | Submission Open
Keywords: gut microbiota; microbiome; differences in gut microflora; molecular techniques; gut microbiota’ s role and composition; healthy state; dysbiosis
(This special issue belongs to the Section Molecular Microbiology)
Glycosylation in Tumor Microenvironment: Roles, Mechanisms and Interventions
edited by
submission deadline 25 Jun 2026 | Viewed by 16 | Submission Open
Keywords: glycoproteins; glycolipids; signaling; cell– cell interaction; cell membrane
(This special issue belongs to the Section Molecular Oncology)
Cancer Stem Cells: Molecular Mechanisms and Therapeutic Targeting
edited by Pablo Pérez-Moreno
submission deadline 25 Jun 2026 | Viewed by 6 | Submission Open
Keywords: cancer stem cells; CSCs clinical biomarkers; CSCs as therapeutic targets; cancer cell biology of CSCs; prognosis and CSCs; molecular biology and CSCs
(This special issue belongs to the Section Molecular Oncology)
Advances in Materials for Water Treatment and Metal/Nutrient Recovery
edited by
submission deadline 25 Jun 2026 | Submission Open
Keywords: water treatment; wastewater treatment; recalcitrant pollutants; metal recovery; nutrient recovery; molecularly engineered materials; functional materials; adsorption and remediation
(This special issue belongs to the Section Materials Science)
Current Research on Cancer Biology and Therapeutics: Fourth Edition submission deadline 29 Jun 2026 | 4 articles | Viewed by 2282 | Submission Open
Keywords: cancer and anticancer peptides; substance P/neurokinin-1 receptor system; neurokinin-1 receptor antagonists
(This special issue belongs to the Section Molecular Oncology)
Plant Growth: Molecular Mechanisms submission deadline 29 Jun 2026 | Viewed by 107 | Submission Open
Keywords: plant growth; hormonal crosstalk; epigenetics; CRISPR/Cas9 genome editing technologies; metabolomics; transcriptomics
(This special issue belongs to the Section Molecular Plant Sciences)
State-of-the-Art Molecular Immunology in Chile, 2nd Edition submission deadline 30 Jun 2026 | 7 articles | Viewed by 15591 | Submission Open
Keywords: innate immunity; adaptive immunity; host– pathogen interactions; immunopathology; osteoimmunology; immunosenescence; immunotherapy; antibody; vaccines; Chile
(This special issue belongs to the Section Molecular Immunology)
Latest Reviews in Molecular Plant Science 2025
edited by and
submission deadline 30 Jun 2026 | 4 articles | Viewed by 10179 | Submission Open
Keywords: gene cloning and gene functional analysis; gene editing; QTL mapping; multi-omics integration analysis; agronomically characteristics; plant development; metabolic pathway; biotic and abiotic stresses
(This special issue belongs to the Section Molecular Plant Sciences)
Wnt/β-Catenin Signaling in Cancer submission deadline 30 Jun 2026 | 1 articles | Viewed by 6809 | Submission Open
Keywords: Wnt/β -catenin pathway; tumors; gene expression; molecular targets; tumor microenvironment; carcinogenesis and metastasis; biomarkers; therapeutic approaches
(This special issue belongs to the Section Molecular Oncology)
Cirrhosis: From Molecular Mechanisms to Therapeutic Strategies
edited by
submission deadline 30 Jun 2026 | 4 articles | Viewed by 6610 | Submission Open
Keywords: liver; fibrogenesis; cirrhosis; portal hypertension; complications; molecular mechanisms; pathway; therapeutic strategies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Preclinical and Translational Research in Thyroid Cancer submission deadline 30 Jun 2026 | 2 articles | Viewed by 5909 | Submission Open
Keywords: thyroid cancers; pathogenesis; molecular bases of thyroid cancer; precision medicine; gender medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Natural Products for Cancer Therapy
edited by María Jesus Rodríguez-Yoldi
submission deadline 30 Jun 2026 | 1 articles | Viewed by 4028 | Submission Open
Keywords: apoptosis; antioxidant; anti-inflammatory; cancer; cell viability; food-by-products; natural products; polyphenols
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Pathogenesis and Antiviral Treatment of Emerging and Reemerging Viral Infections submission deadline 30 Jun 2026 | 1 articles | Viewed by 3035 | Submission Open
Keywords: viral replication; antiviral; inflammation; vaccine; arbovirus; respiratory virus; hemorrhagic virus; neurotropic virus
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Hormone Receptor in Breast Cancer: 2nd Edition submission deadline 30 Jun 2026 | 2 articles | Viewed by 2757 | Submission Open
Keywords: estradiol; progesterone; calcitriol; androgen; resveratrol; phytoestrogens; therapeutic targets; fulvestrant; treatment response; SERM; estrogen receptor isoforms; selective ligands; hormonal carcinogenesis; breast cancer prevention; hormone signaling; endocrine disruptor compounds; ER-negative breast cancer; ER-positive breast cancer; aromatase inhibitors
(This special issue belongs to the Section Molecular Oncology)
Molecular Endocrine Regulation in Health and Diseases
edited by Fady Hannah-Shmouni
submission deadline 30 Jun 2026 | 1 articles | Viewed by 2693 | Submission Open
Keywords: exposome and endocrine disruptors; endocrine-disrupting chemicals (EDCs); environmental toxicology and hormonal health; epigenetics and endocrine function; endocrine regulation and chronic disease; public health and exposure mitigation; endocrine disruptors in the home and community
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Functional Genomics and Molecular Mechanisms of Plant Stress Responses
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 699 | Submission Open
Keywords: plant stress responses; abiotic stress; biotic stress; molecular mechanisms; functional genomics
(This special issue belongs to the Section Molecular Plant Sciences)
Oxidative Stress Unveiled: Mechanisms and Implications in Cardiac Pathologies
edited by Sukkum Ngullie Chang and Vernat Exil
submission deadline 30 Jun 2026 | Viewed by 553 | Submission Open
Keywords: reactive oxygen species (ROS); electron transport chain (ETC); mitochondrial permeability transition pore (mPTP); endothelial– cardiomyocyte– fibroblast crosstalk; metabolic adaptation; inflammation; cardiovascular disease (CVD)
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
RNA Modifications in Response to Physical Activity: Implications for Rehabilitation and Disease Management
edited by Roberto Tedeschi and Francesca Gorini
submission deadline 30 Jun 2026 | Viewed by 356 | Submission Open
Keywords: RNA modifications; non-coding RNAs (ncRNAs); physical activity; gene expression; rehabilitation and disease management; epigenetic regulation; exercise-induced RNA expression; miRNA in inflammation control
(This special issue belongs to the Section Molecular Biology)
Genetic Regulation of Plant Growth and Protection (2nd Edition)
edited by and
submission deadline 30 Jun 2026 | Viewed by 197 | Submission Open
Keywords: molecular regulation; genetic resources; functional genomics; plant growth and development; abiotic and biotic stresses; plant– microbe interactions
(This special issue belongs to the Section Molecular Plant Sciences)
Advances in Molecular Genetics and Molecular Therapy for Gastric Cancers
edited by
submission deadline 30 Jun 2026 | Viewed by 179 | Submission Open
Keywords: gastric cancer; molecular genetics; targeted therapy; tumor microenvironment; immunotherapy; biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Biomaterials and Nanotechnology in Cancer Therapy and Regenerative Medicine
edited by Manoochehr Rasekh
submission deadline 30 Jun 2026 | Viewed by 162 | Submission Open
Keywords: biomaterials; nanoparticle drug delivery; cancer therapy; stimuli-responsive nanocarriers; targeted therapeutics; regenerative medicine; tissue engineering; theranostics
(This special issue belongs to the Section Materials Science)
Nanodrug Bioavailability and Biocompatibility in Cancer and CNS Disorders submission deadline 30 Jun 2026 | Viewed by 150 | Submission Open
Keywords: nanomedicine; bioavailability; biocompatibility; tumor microenvironment; Blood– Brain Barrier; targeted drug delivery; neurodegenerative diseases
(This special issue belongs to the Section Molecular Nanoscience)
Unraveling Neurodevelopmental Disorders: A Molecular Perspective
edited by Marija-Magdalena Petrinovic
submission deadline 30 Jun 2026 | Viewed by 112 | Submission Open
Keywords: neurodevelopmental disorders; molecular neuroscience; genetics; epigenetics; functional MRI (fMRI); magnetic resonance spectroscopy (MRS); PET imaging; imaging biomarkers; translational neuroscience; precision medicine
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Mechanism and Therapeutics in Human Cancer
edited by
submission deadline 30 Jun 2026 | Viewed by 110 | Submission Open
Keywords: oncogenes; Wnt/b-catenin; G-protein-coupled receptors (GPCR); translational means; cancer stem cells; ubiquitination and deubiquitinating in cancer
(This special issue belongs to the Section Molecular Oncology)
From DNA Damage to Cell Death: Emerging Drug Targets and Therapeutic Opportunities
edited by and Beata Marciniak
submission deadline 30 Jun 2026 | Viewed by 107 | Submission Open
Keywords: apoptosis; cancer therapy; cell death pathways; chemoresistance; DNA damage response (DDR); DNA repair inhibitors; drug discovery; ferroptosis; genomic instability; therapeutic targets
(This special issue belongs to the Section Molecular Biology)
Mitigating Metal Toxicity: Contaminated Environment, Animal Studies and Human Health submission deadline 30 Jun 2026 | Viewed by 105 | Submission Open
Keywords: heavy metal toxicity; heavy metal pollution; heavy metal bioaccumulation and interactions; health risk; mechanistic analysis; dysregulation of cellular homeostasis; natural plant bioactive compounds; human diseases; environmental pollution; in vitro/animal studies; innovative strategies; polyoxometalates (POMs); metal-organic frameworks (MOFs)
(This special issue belongs to the Section Molecular Toxicology)
Gynaecological Diseases: From Emergence to Translational Medicine
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 99 | Submission Open
Keywords: gynaecological diseases; reproductive biology; endometriosis; ovarian dysfunction
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Discoveries in Pharmacogenetics: From Bench to Bedside submission deadline 30 Jun 2026 | Viewed by 98 | Submission Open
Keywords: pharmacogenetics; clincial practice; artficial intelligence; bioinformatics; personalized medicine; drug response; genetic variations
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Mechanisms of Human Liver Diseases: 3rd Edition
edited by
submission deadline 30 Jun 2026 | Viewed by 95 | Submission Open
Keywords: non-alcoholic fatty liver disease (NAFLD); non-alcoholic steatohepatitis (NASH); alcoholic steatohepatitis (ASH); Wilson’ s disease; hemochromatosis; viral hepatitis; autoimmune hepatitis; hepatocellular carcinoma; signaling pathways; molecular mechanisms; metabolic dysfunction-associated steatotic liver disease (MASLD); metabolic dysfunction-associated steatohepatitis (MASH)
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Thermogenic Adipocytes and Skeletal Muscle: Novel Molecular Targets for the Treatment of Diabetes and Obesity
edited by
submission deadline 30 Jun 2026 | Viewed by 83 | Submission Open
Keywords: metabolic diseases; obesity; type 2 diabetes; molecular signaling pathway
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Latest Research Progress of Biomaterial Modification
edited by
submission deadline 30 Jun 2026 | Viewed by 80 | Submission Open
Keywords: functionalization of carbohydrates; molecular aggregation; simulation of biopolymers; biopolymeric microcapsules; biopolymeric devices
(This special issue belongs to the Section Materials Science)
Molecular Insights into the Stability and Degradation of Perovskite Solar Cells
edited by
submission deadline 30 Jun 2026 | Viewed by 75 | Submission Open
Keywords: perovskite; thin films; solar cells; PCE; stability; molecular structure evolution (perovskite); perovskite precursor molecular design
(This special issue belongs to the Section Materials Science)
Preparation and Applications of Colloidal Emulsions
edited by
submission deadline 30 Jun 2026 | Viewed by 75 | Submission Open
Keywords: emulsions; fabrication; characterization; applications; encapsulation; delivery systems
(This special issue belongs to the Section Molecular Biology)
Advances in Alzheimer’s Disease
edited by
submission deadline 30 Jun 2026 | Viewed by 72 | Submission Open
Keywords: Alzheimer’ s Disease; amyloid beta; molecular target
(This special issue belongs to the Section Molecular Neurobiology)
Anesthetics and Neurovascular Health: Molecular Pathways
edited by Gabriele Melegari
submission deadline 30 Jun 2026 | Viewed by 70 | Submission Open
Keywords: neurovascular paths; blood– brain barrier (BBB) and anesthesia; neurovascular coupling; perioperative neuroprotection; neuroinflammation; endothelial dysfunction; cerebral autoregulation; cerebral blood flow; perioperative brain health
(This special issue belongs to the Section Molecular Neurobiology)
Advanced Functional Materials for Catalysis and Storage
edited by
submission deadline 30 Jun 2026 | Viewed by 59 | Submission Open
Keywords: functional materials; energy catalysis; small molecule conversion; energy storage
(This special issue belongs to the Section Materials Science)
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