Hepatitis Virus Infection and Research

Dear Colleagues,

Welcome to this Special Issue, “Hepatitis Virus Infection and Research”, of the International Journal of Molecular Sciences. Infections of hepatitis A virus (HAV), HBV, HCV, HDV, and HEV are still a serious issue worldwide, although effective vaccines for HAV and HBV have been developed. HAV and HBV are major causes of acute hepatitis, including acute hepatic failure (ALF). The mechanism of hepatocarcinogenesis in HBV and HCV infections is still unclear. Effective interferon-free treatment against HCV is now available, but it has led to several problems, such as the occurrence of hepatocellular carcinoma (HCC) after sustained virological response, non-response to direct-acting antivirals, and treatment of decompensated cirrhosis. HEV causes ALF, but the root of HEV infection is still unclear in certain cases and chronic HEV infection has been reported in transplant patients. Thus, taken together, it is clear that a lot of issues still exist in clinical practice and basic research areas. This Special Issue will present the latest findings related to viral hepatitis, the association with HCC, and so on. Original research and review articles on all topics in this area are invited. It is my greatest pleasure to invite research scientists and clinicians from all relevant fields to submit their articles for this Special Issue. Please accept my special thanks for choosing to publish in the International Journal of Molecular Sciences. I am looking forward to your submissions for this highly important Special Issue.

Dr. Tatsuo Kanda
Guest Editor

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