Old and New Gateways to Liver Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 November 2024) | Viewed by 1395
Special Issue Editors
Interests: viral hepatitis; hepatocellular carcinoma; innate immunity; unfolded protein response
Special Issues, Collections and Topics in MDPI journals
Interests: viral hepatitis; hepatocellular carcinoma; liver diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Molecular mechanisms and molecular targets are important in the field of liver diseases, including acute and chronic liver diseases, cirrhosis, and hepatocellular carcinoma. Alcohol-associated liver disease (ALD) and metabolic dysfunction-associated fatty liver disease (MAFLD) represent a spectrum of liver injuries resulting from alcohol use and metabolic diseases, respectively. They are charactrized by hepatic steatosis. Viral hepatitis is also a major issue. Although these liver diseases have traditionally been known, new gateways should be opened to diagnose and treat these diseases. Therapeutic options of immune checkpoint inhibitors (ICIs) with or without tyrosine kinase inhibitors (TKIs) are effective for advanced hepato-biliary-pancreatic malignancies, including hepatocellular carcinoma. The adverse events of these therapies also constitute a serious problem. In recent years, the clinical trials of therapeutic drugs for cirrhosis are advanced. In this Special Issue, we will focus on the wide range of liver diseases, especially their underlying molecular mechanisms.
Dr. Tatsuo Kanda
Dr. Reina Sasaki
Guest Editors
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Keywords
- autoimmune liver diseases
- chemotherapy
- ICIs
- TKIs
- trace elements
- viral hepatitis
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