Special Issue "Hepatitis and Treatment"
Deadline for manuscript submissions: closed (30 September 2018)
After interferon-free regimens with combinations of direct-acting antivirals (DAAs), against hepatitis C virus (HCV), appeared, higher sustained virologic response (SVR) rates were achieved compared to those of interferon-including regimens. HCV can be eradicated more easily with less adverse events, however, as some HCV-infected patients become older and some have advanced liver diseases, the occurrence and recurrence of hepatocellular carcinoma (HCC) is sometimes observed after SVR. Thus, different problems in the interferon-era have appeared. In patients infected with the hepatitis B virus (HBV), it has been easy to control virus replication, but the occurrence of HCC is still one of the major problems. Acute exacerbation and reactivation of HBV cannot be predicted, with or without the use of immunosuppressants and/or anti-cancer drugs. Hepatocarcinogenesis in non-viral liver diseases is also an important problem. This Special Issue will focus on the study of hepatitis, its treatment, and others.
Dr. Tatsuo Kanda
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