Special Issue "Molecular Pharmacology and Pathology of Strokes"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 January 2019)
A printed edition of this Special Issue is available here.
Prof. Dr. Joen-Rong Sheu
Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan
Website | E-Mail
Interests: clinical and translational research; free radicals and oxidative stress; inflammation and microglia; neuroregeneration and neurodegeneration; novel drug development (bioactive and chemical synthesis) for treatment of stroke; pathological mechanisms; platelet activation and arterial thrombosis; hyperlipidemia and vascular diseases
Stroke is an acute neurological event leading to neural tissue death in the brain, causing motor, sensory, and cognitive function loss. It is the second leading cause of death after coronary heart disease in developed countries. Despite the major advancements in cerebrovascular medicine over the past 50 years, stroke remains the number one public health concern and primary causes of death today. Breakthroughs in elucidating the basic molecular pharmacology in cerebrovascular function and thrombosis/coagulation, has led to significant advancements in the current treatment paradigm for patients with stroke. Innovation in these areas of research has led to remarkable discoveries and significantly reduced the mortality and morbidity from stroke. Nevertheless, more work and a tenacious pursuit of the basic/clinical sciences in cerebrovascular pathology and pharmacology are still wanted. The purpose of this Special Issue is to present knowledge of prevention and treatment by the use of novel drugs and nutraceuticals, with the help of our co-workers and globally-associated researchers. We encourage contribution by original research articles, as well as review articles, which will motivate the remaining efforts to understand the pathology underlying cerebrovascular diseases, and neurodegenerations, the development of strategies to prevent and treat these conditions, evaluation of outcomes, and epidemiological and clinical studies.
Prof. Dr. Joen-Rong Sheu
Prof. Dr. Howard Prentice
Manuscript Submission Information
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- platelet activation and thrombosis
- vascular diseases
- novel drug development
- pathogenic mechanisms
- free radicals/oxidative stress
- signal transductions
- clinical and translational research