Special Issue "Natural and Semi-Synthetic Small Molecules in Drug Discovery"
Deadline for manuscript submissions: closed (30 September 2018).
Small molecules continue to be the most relevant set of therapeutic options for most human pathologies.
The process of drug discovery is complex and can arise from several strategies; however, naturally-occurring molecules are still one of the most prolific sources new chemical entities with application in human health. However, these molecules can frequently be upgraded or enhanced in their potency and selectivity by conducting structural changes. For this reason, derivatives obtained by hemisynthesis are also pivotal players in the process of drug discovery and development.
This Special Issue will focus in the process of drug discovery from naturally-occurring bioactive small molecules and also their hemisynthetic derivatives. Several diseases will be addressed including, but not limited to, cancer, as well as inflammatory, neurodegenerative and metabolic diseases.Prof. Dr. David Pereira
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Bioactive small molecules
- Natural molecules
- Natural products chemistry
- Medicinal chemistry
- Neurodegenerative diseases
- Metabolic diseases