Journal Menu► ▼ Journal Menu
Journal Browser► ▼ Journal Browser
Special Issue "Pain and Inflammation"
Deadline for manuscript submissions: closed (31 December 2017).
Prof. Dr. Irmgard Tegeder Website E-Mail
Pharmazentrum Frankfurt, Dept. of Clinical Pharmacology, Goethe-University of Frankfurt, Theodor Stern Kai 7, Bd. 74, 4th Fl, 60590 Frankfurt am Main, Germany
Interests: nerve injury and neuropathic pain; pain and aging; central adaptations to chronic pain; multiple sclerosis; neuroinflammation; neuro-immunologic communication; redox signaling; nitric oxide; endocannabinoids and other lipid signaling molecules; progranulin; autophagy
A growing number of molecules have been suggested to contribute to the development of chronic inflammation and pain, and some of them bear some potential as drug targets based on rodent models. However, the mechanisms are not fully understood, and, traditionally, therapeutic approaches have mainly sought to antagonize the pro-inflammatory players of inflammation, with mixed success. More recently, molecular mechanisms that initiate the resolution of inflammation have opened a new avenue in pro-resolution strategies to treat complex chronic inflammatory diseases. However, resolution pathways are heterogeneous and probably tissue- and stimulus-specific. A better understanding of the balance between pro-inflammation and pro-resolution strategies addressing for example cell-to-cell receptor binding and bioactive lipid mediators are needed to develop novel therapeutic strategies.
In this Special Issue we invite original research and reviews in the field of pain and inflammation, particularly addressing molecular mechanisms of inflammation persistence versus resolution.
Prof. Dr. Irmgard Tegeder
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- resolution of inflammation
- bioactive lipids
- immune cells
- redox signaling
- macrophage polarization