Special Issue "Non-Alcoholic Fatty Liver Disease Research"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 August 2013) | Viewed by 130420
Interests: liver diseases; non-alcoholic fatty liver disease; hepatocellular carcinoma; epigenetic mechanisms; microRNAs
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Non-alcoholic fatty liver disease (NAFLD) is one of most common chronic liver disease worldwide. The close relationship with epidemic obesity and metabolic syndrome, and the potential progression towards end-stage liver diseases, such as cirrhosis and HCC, makes of NAFLD an emerging global health problem. The assessment of the multifaceted histological/biochemical pattern that characterizes NAFLD and the comprehension of possible complex pathogenetic events/factors involved in the step-by-step manifestation of the specific traits that define this disease are an exciting challenge. New discoveries in this field are, in fact, the optimal start-point to design novel efficient diagnostic and therapeutic approaches for NAFLD.
We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the pathogenesis of NAFLD and its impact on disease management.
Potential topics could include, but are not limited to:
- Role of epigenetics and genetics in the development of NAFLD
- Cellular and molecular networks involved in NAFLD development and its progression towards liver fibrosis and cancer
- Relationships between obesity/metabolic syndrome and NAFLD: the role of gut
- In vitro and in vivo animal models that mimic human NAFLD
- Diagnostic approaches and novel potential “omics” biomarkers
- Therapeutic interventions in NAFLD development and progression
Dr. Anna Alisi
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access semimonthly journal published by MDPI.
- NAFLD pathogenesis
- NAFLD-related HCC
- genetic background
- NAFLD experimental models