Special Issue "Transcriptional Regulation in Lipid Metabolism"
Deadline for manuscript submissions: closed (30 September 2018).
Interests: energy homeostasis; lipid metabolism; transcription factor; CREBH; SREBP; hyperlipidemia; diabetes; atherosclerosis
Special Issues and Collections in MDPI journals
In recent years, with the increase in calorie expropriation and lack of exercise, patients with lifestyle diseases have been increasing, and this matter is becoming a social problem all over the world. Lipid metabolism has a crucial role in the pathology of these diseases. The abnormality of lipid metabolism deteriorates to hyperlipidemia, obesity, diabetes, nonalcoholic fatty liver (NAFLD), eventually coronary artery disease, and develops a life crisis. Thus, its elucidation is important for the improvement of lifestyle diseases. Dysregulation in lipid metabolism is caused by the accumulation of abnormalities at long-term gene expression levels. Therefore, an understanding at the transcriptional level is necessary. In this review, we would like to talk about the molecular mechanism of lipid metabolism regulation from crosstalk between transcription factors controlling gene expression involved in lipid metabolism. Among new findings in the regulation of gene expression related to lipid metabolism, we need to think about ways to treat lifestyle diseases in the future.
Dr. Yoshimi Nakagawa
Prof. Dr. Hitoshi Shimano
Manuscript Submission Information
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- Lipid metabolism
- Glucose metabolism
- Transcription factor interaction
- Gene expression
- Fatty liver