Bioactive Phytochemicals for Cancer Prevention and Treatment II

Dear Colleagues,

Plants have been an important source of bioactive phytochemicals since historic times. Phytochemicals are synthesized by plants as their defensive mechanisms. Several epidemiological studies indicate an inverse correlation between the intake of specific plant foods and cancer incidence. Thousands of phytochemicals have been identified to date, but only a few have been explored in depth for their beneficial roles. Phytochemicals available from dietary plant sources can be classified based on their chemical structures. For example, isothiocyanates, indoles, carotenoids, flavonoids, isoflavones, and terpenoids are some of the major classes studied for their anticancer effects. Phytochemicals are considered to be advantageous over the current chemotherapeutic options available. This is because cancer etiology involves multiple mechanisms, and phytochemicals, being pleiotropic, can counter more procarcinogenic mechanisms. Moreover, being a component of dietary plants, phytochemicals are also relatively nontoxic and generally have broader safety windows. Combination therapy is evitable in clinical practice. Several phytochemicals have been shown to enhance the effects of chemotherapeutic drugs. This Special Issue has been envisaged to document studies on well-known phytochemicals and their role in cancer prevention. The articles in this issue come from eminent researchers in the field of cancer chemoprevention from all around the world. This Issue will be beneficial to all the basic, clinical, and applied researchers and physicians interested in cancer chemoprevention and chemotherapeutics.

Prof. Sanjay K. Srivastava
Prof. Dr. Sung-Hoon Kim
Guest Editors

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