Transglutaminase Diseases, from the Experimental Laboratory to Human Pathology Applications 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 21256
Special Issue Editors
Interests: experimental oncology; biochemistry
Special Issues, Collections and Topics in MDPI journals
Interests: biochemistry; molecular biology; medical genetics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is the second volume of our previous Special Issue "Transglutaminase Diseases, from the Experimental Laboratory to Human Pathology Applications". Transglutaminases are ubiquitous enzymes which catalyze posttranslational modifications of proteins. Recently, transglutaminase-catalyzed posttranslational modification of proteins has been shown to be involved in the molecular mechanisms responsible for human diseases. This family of enzymes has been associated with inflammation, cancer, fibrosis, cardiovascular disease, and celiac disease, in which it plays either a protective role or contributes to the pathogenesis. Transglutaminase activity has been hypothesized to also be involved in the pathogenetic mechanisms responsible for several human neurodegenerative diseases. Alzheimer’s disease and other neurodegenerative diseases, such as Parkinson’s disease, supranuclear palsy, Huntington’s disease, and other polyglutamine diseases, are characterized in part by aberrant cerebral transglutaminase activity and by increased cross-linked proteins in affected brains.
We are pleased to invite you to contribute to the Special Issue, “Transglutaminase Diseases, from the Experimental Laboratory to Human Pathology Applications 2.0", which will be published in the International Journal of Molecular Sciences (IF 4.556), an international peer-reviewed open access journal providing an advanced forum for biochemistry, molecular and cell biology, and molecular biophysics, published semi-monthly online by MDPI. Citations are available in PubMed, and full texts are archived in PubMed Central. The objective of this Special Issue is to collect and publish both experimental and theoretical contributions from original and high-quality research articles and to encourage researchers to investigate topics in the field of transglutaminases in various diseases.
Prof. Dr. Simone Beninati
Dr. Carlo Mischiati
Guest Editors
Manuscript Submission Information
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