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Special Issue "Transglutaminases in Health and Disease"
A special issue of Medical Sciences (ISSN 2076-3271).
Deadline for manuscript submissions: closed (31 October 2018).
Interests: experimental oncology; biochemistry
Special Issues and Collections in MDPI journals
Interests: molecular medicine, molecular mechanisms of disease pathogenesis, development of molecular diagnosis, novel approaches to rational treatment.
Transglutaminases belong to a large family of intracellular and extracellular Ca2+- dependent enzymes, which catalyze the post-translational modification of many substrate proteins. At present, significant progress has been made in understanding the biological role of most mammalian transglutaminase isoforms. Recent findings suggest new scenarios, in particular for ubiquitous tissue transglutaminase. In fact, several studies have shown that some transglutaminases normally present at low levels in many tissues, are activated and/or overexpressed in a wide variety of human diseases thus paving the way for new therapeutic possibilities. In addition, as with all enzymes that exert their metabolic function by modifying properties of target proteins, the identification and the characterization of the modified proteins will allow to shed new light on the functions of the transglutaminase and to understand better their involvement in human diseases.
In light of this, I am pleased to invite you to contribute to this Special Issue, "Transglutaminases in Health and Disease", which will be published in the international journal Medical Sciences. Medical Sciences is an international open access scientific journal, providing platform for advances in basic, translational and clinical research. Citations are available in PubMed and full-text are archived in PubMed Central. The journal aims is to publish original research, review articles and short communications about molecular and cellular processes in disease, in order to increase understanding of the fundamental principles and biological questions of medicine. The objectives of this Special issue on "Transglutaminases in Health and Disease" are to publish and collect both experimental and theoretical contributions from original and high-quality research articles and encourage researchers to investigate topics in the field of transglutaminases in various diseases.
Prof. Simone Beninati
Lead Guest Editor
Prof. Carlo Mischiati
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medical Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.