Natural Products and Oral Health: Challenges and Opportunities
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: closed (25 July 2024) | Viewed by 1083
Special Issue Editors
Interests: natural extracts; bioactive compounds; antioxidants; in vitro assays; in vivo cosmetic assays; pharmaceutics
Special Issues, Collections and Topics in MDPI journals
Interests: encapsulation; drug delivery systems; modified drug delivery; pharmaceutics
Special Issue Information
Dear Colleagues,
Oral diseases encompass a range of diseases and conditions that include periodontal (gum) disease, oral mucositis (OM), oral cancer, etc., which are among the most common noncommunicable diseases worldwide. The use of bioactive compounds extracted from natural sources with biological properties is an interesting approach to prevent/treat oral diseases and their related complications, such as OM.
Recently, attention has been paid to polyphenols and their positive effects against oral diseases in human trials, due to their antioxidant, anti-inflammatory, or anti-proliferative activities.
Therefore, the use of bioactive compounds extracted from natural sources with biological properties may be an approach to prevent/treat oral diseases and, most importantly, discover new potential compounds. Importantly, targeting metabolic, oxidative stress, and mitochondrial pathways could provide disease-selective natural compounds.
However, the orally absorbed bioactive compound concentration is often low, avoiding an acceptable therapeutic effect. Other drawbacks regarding the pharmacokinetics (PK) profile or stability across the gastrointestinal tract (GIT) may occur. Encapsulation could be a strategy to prevent such problems and improve buccal delivery.
This Special Issue of IJMS invites research articles, reviews, and opinion reviews on fascinating advancements in the area of the efficacy of natural compounds for oral diseases and their related complications.
Dr. Francisca Rodrigues
Dr. Paulo Cardoso Da Costa
Guest Editors
Manuscript Submission Information
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Keywords
- phytochemicals
- natural compounds
- antitumor activity
- oral mucositis
- encapsulation
- drug delivery systems
- oxidative stress
- metabolic pathways
- protein expression
- cellular signaling
- cancer prevention
- immunomodulation
- adjuvant therapy
- preventive therapy
